Monte Carlo-Minimized energy profile of estradiol in the ligand- binding tunnel of 17β-hydroxysteroid dehydrogenase: Atomic mechanisms of steroid recognition

Proteins: Structure, Function and Genetics

Volumn 38, Issue 4, 2000, Pages 414-427

  Zhorov, Boris S ^a   Lin, Sheng Xiang ^b  

^a MCMASTER UNIVERSITY   (Canada)

^b NONE

Author keywords

Breast cancer; Computer simulation; Drug design; Molecular modeling; Steroid hormones

Indexed keywords

ESTRADIOL; TESTOSTERONE 17BETA DEHYDROGENASE;

ARTICLE; CONFORMATIONAL TRANSITION; ENZYME SUBSTRATE COMPLEX; MOLECULAR MODEL; PRIORITY JOURNAL; SYSTEM ANALYSIS;

17-HYDROXYSTEROID DEHYDROGENASES; AMINO ACID SEQUENCE; CRYSTALLOGRAPHY, X-RAY; ESTRADIOL; LIGANDS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MONTE CARLO METHOD; PROTEIN BINDING; PROTEIN CONFORMATION;

EID: 0034003769     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0134(20000301)38:4<414::AID-PROT7>3.0.CO;2-X     Document Type: Article

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