Structure of 3α-hydroxysteroid/dihydrodiol dehydrogenase complexed with NADP+

Biochemistry

Volumn 35, Issue 33, 1996, Pages 10702-10711

  Bennett, Melanie J ^a   Schlegel, Brian P ^a   Jez, Joseph M ^a   Penning, Trevor M ^a   Lewis, Mitchell ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3ALPHA HYDROXYSTEROID DEHYDROGENASE; DIHYDRODIOL DEHYDROGENASE; LIVER ENZYME; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; ENZYME ANALYSIS; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

3-HYDROXYSTEROID DEHYDROGENASES; ANIMALS; BINDING SITES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; LIVER; MALE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NADP; RATS; RATS, SPRAGUE-DAWLEY; STEROIDS;

EID: 0029764218     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9604688     Document Type: Article

References (49)

1. Askonas, L. J., Ricigliano, J. W., & Penning, T. M. (1991) Biochem. J. 278, 835-841.
2. Bohren, K. M., Grimshaw, C. E., & Gabbay, K. H. (1992) J. Biol. Chem. 267, 20965-20970.
3. Bohren, K. M., Grimshaw, C. E., Lai, C.-J., Harrison, D. H., Ringe, D., Petsko, G. A., & Gabbay, K. H. (1994) Biochemistry 33, 2021-2032.
4. Borhani, D. W., Harter, T. M., & Petrash, J. M. (1992) J. Biol. Chem. 267, 24841-24847.
5. Bowie, J. U., Luthy, R., & Eisenberg, D. (1991) Science 253, 164-170.
6. Bruce, N. C., Willey, D. L., Coulson, A. F. W., & Jeffery, J. (1994) Biochem. J. 299, 805-811.
7. Brunger, A. T. (1992a) X-PLOR Version 3.1: A system for X-ray crystallography and NMR, Yale University Press, New Haven, CT.
8. Brunger, A. T. (1992b) Nature 355, 472-475.
9. Chen, Z., Jiang, J. C., Lin, Z.-G., Lee, W. R., Baker, M. E., & Chang, S. H. (1993) Biochemistry 32, 3342-3346.
10. Collaborative Computational Crystallography Project, Number 4 (1994) Acta Crystallogr. D 50, 760-763.
11. Deyashiki, Y., Ogasawara, A., Nakayama, T., Nakanishi, M., Miyabe, Y., Sato, K. & Hara, A. (1994) Biochem. J. 299, 545-552.
12. Deyashiki, Y., Ohshima, K., Nakanishi, M., Sato, K., Matsuura, K., & Hara, A. (1995) J. Biol. Chem. 270, 10461-10467.
13. Dufort, I., Soucy, P., Zhang, Y., & Luu-The, V. (1995) Cloning and characterization of human type 2 3α-hydroxysteroid dehydrogenase from human prostatic cDNA library, Fifth International Congress, Hormones and Cancer, Quebec City, Canada.
14. El-Kabbani, O., Judge, K., Ginell, S. L., Myles, D. A. A., DeLucas, L. J., & Flynn, T.G. (1995) Nat. Struct. Biol. 2, 687-692.
15. Ensor, C. M., & Tai, H.-H. (1991) Biochem. Biophys. Res. Commun. 176, 840-845.
16. Evans, S. V. (1993) J. Mol. Graphics 11, 134-138.
17. Furey, W., & Swaminathan, S. (1990) PHASES - a program package for the processing and analysis of diffraction data for macromolecules, American Crystallographic Association Meeting, New Orleans, LA.
18. Ghosh, D., Wawrzak, Z., Weeks, C. M., Duax, W. L., & Erman, M. (1994) Structure 2, 629-640.
19. Ghosh, D., Pletnev, V. Z., Zhu, D.-W., Wawrzak, Z., Duax, W. L., Pangborn, W., Labrie, F., & Lin, S.-X. (1995) Structure 3, 503-513.
20. Harrison, D. H., Bohren, K. M., Ringe, D., Petsko, G. A., & Gabbay, K. H. (1994) Biochemistry 33, 2011-2020.
21. Hoog, S. S., Pawlowski, J. E., Alzari, P. M., Penning, T. M., & Lewis, M. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 2517-2521.
22. Jez, J. M., & Penning, T. M. (1995) The Role of Tryptophans in Ligand Recognition by Rat Liver 3α-Hydroxysteroid Dehydrogenase, International Symposium on DHEA Transformation into Androgens and Estrogens in Target Tissues, Quebec City, Canada.
23. Jones, T. A., Zou, J.-Y., Cowan, S. W., & Kjeldgaard, M. (1991) Acta Crystallogr. A 47, 110-119.
24. Jornvall, H., Persson, B., Krook, M., Atrian, S., Gonzalez-Duarte, R., Jeffery, J., & Ghosh, D. (1995) Biochemistry 34, 6003-6013.
25. Kabsch, W. (1988) J. Appl. Crystallogr. 21, 916-924.
26. Khanna, M., Qin, K.-N., Wang, R. W., & Cheng, K.-C. (1995) J. Biol. Chem. 270, 20162-20168.
27. Kraulis, P. (1991) J. Appl. Crystallogr. 24, 946-950.
28. Lacy, W. R., Washenick, K. J., Cook, R. G., & Dunbar, B. S. (1993) Mol. Endocrinol. 7, 58-66.
29. Laskowski, R. A., MacArthur, M. W., Moss, D. S., & Thornton, J. M. (1993) J. Appl. Crystallogr. 26, 283-291.
30. Leslie, A. G. W. (1992) CCP 4 and ESF-EAC MB Newsletter on Protein Crystallography, Vol. 26.
31. Lin, H.-K., Jez, J. M., & Penning, T. M. (1995) Cloning of a human prostate cDNA with high sequence identity to rat liver 3α-hydroxysteroid/dihydrodiol dehydrogenase, International Symposium on DHEA Transformation into Androgens and Estrogens in Target Tissues, Quebec City, Canada.
32. Liu, S.-Q., Bhatnagar, A., & Srivastava, S. K. (1993) J. Biol. Chem. 268, 25494-25499.
33. Matthews, B. W. (1968) J. Mol. Biol. 33, 491-497.
34. Miura, R., Shiota, K., Noda, K., Yagi, S., Ogawa, T., & Takahashi, M. (1994) Biochem. J. 299, 561-567.
35. Mukharji, I. (1982) Ph.D. Dissertation, The Johns Hopkins University, Baltimore, MD.
36. Obeid, J., & White, P. C. (1992) Biochem. Biophys. Res. Commun. 188, 222-227.
37. Pawlowski, J. E., & Penning, T. M. (1994) J. Biol. Chem. 269, 13502-13510.
38. Pawlowski, J. E., Huizinga, M., & Penning, T. M. (1991) J. Biol. Chem. 266, 8820-8825.
39. Penning, T. M. (1993) Chem.-Biol. Interact. 89, 1-34.
40. Penning, T. M., Mukharji, I., Barrows, S., & Talalay, P. (1984) Biochem. J. 222, 601-611.
41. Penning, T. M., Ohnishi, T., Ohnishi, T. S., & Harvey, R. G. (1996) Chem. Res. Toxicol. 9, 84-92.
42. Rondeau, J. M., Tete-Favier, F., Podjarny, A, Reymann, J. M., Barth, P., Biellmann, J. F., & Moras, D. (1992) Nature 355, 469-472.
43. Rossmann, M. G., Moras, D., & Olsen, K. W. (1974) Nature 250, 194-199.
44. Smithgall, T. E., Harvey, R. G., & Penning, T. M. (1988) J. Biol. Chem. 263, 1814-1820.
45. Stolz, A., Hammond, L., Lou, H., Takikawa, H., Ronk, M., & Shively, J. E. (1993) J. Biol. Chem. 268, 10448-10457.
46. Varughese, K. I., Skinner, M. M., Whiteley, J. M., Matthews, D. A., & Xuong, N. H. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 6080-6084.
47. Wilson, D. K., Bohren, K. M., Gabbay, K. H., & Quiocho, F. A. (1992) Science 257, 81-84.
48. Wilson, D. K., Tarle, I., Petrash, J. M., & Quiocho, F. A. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 9847-9851.
49. Wilson, D. K., Nakano, T., Petrash, J. M., & Quiocho, F. A. (1995) Biochemistry 34, 14323-14330.