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Biochemistry

Volumn 40, Issue 40, 2001, Pages 12112-12122

Ticlopidine as a selective mechanism-based inhibitor of human cytochrome P450 2C19

(6) Ha Duong, N T a Dijols, S a Macherey, A C a Goldstein, J A b Dansette, P M a Mansuy, D a

a UNIVERSITÉ PARIS DESCARTES (France)

b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INACTIVATION;

ALKYLATION; ENZYME INHIBITION; METABOLITES; OXIDATION; PROTEINS; TOPOLOGY; YEAST;

CYTOLOGY;

2 HYDROXYTICLOPIDINE; AMINE; CHLOROPHENOL; CYTOCHROME P450 2C19; GLUTATHIONE; OMEPRAZOLE; TICLOPIDINE; TICLOPIDINE S OXIDE; TIENILIC ACID; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; CATALYSIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; COVALENT BOND; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME KINETICS; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER; METABOLITE; OXIDATION; PRIORITY JOURNAL; PROTEIN INTERACTION; ULTRAVIOLET RADIATION;

ALKYLATION; ARYL HYDROCARBON HYDROXYLASES; BINDING SITES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INHIBITORS; GLUTATHIONE; HUMANS; KINETICS; LIVER; MIXED FUNCTION OXYGENASES; MOLECULAR STRUCTURE; OMEPRAZOLE; RECOMBINANT PROTEINS; SPECTRUM ANALYSIS; TICLOPIDINE;

EID: 0035834052 PISSN: 00062960 EISSN: None Source Type: Journal
DOI: 10.1021/bi010254c Document Type: Article

Times cited : (159)

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