Comparison of the substrate specificities of human liver cytochrome P450s 2C9 and 2C18: Application to the design of a specific substrate of CYP 2C18

Biochemistry

Volumn 38, Issue 24, 1999, Pages 7828-7836

  Minoletti, Claire ^a   Dijols, Sylvie ^a   Dansette, Patrick M ^a   Mansuy, Daniel ^a  

^a CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

3 [2,3 DICHLORO 4 (2 THENOYL)PHENOXY]PROPAN 1 OL; ALCOHOL; CYTOCHROME P450 2C18; CYTOCHROME P450 2C9; CYTOCHROME P450 ISOENZYME; LIVER ENZYME; THIOPHENE DERIVATIVE; TIENILIC ACID; UNCLASSIFIED DRUG;

ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME SPECIFICITY; ENZYME SUBSTRATE; HUMAN; HYDROXYLATION; PRIORITY JOURNAL;

ARYL HYDROCARBON HYDROXYLASES; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 CYP2D6; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 ENZYME SYSTEM; HUMANS; HYDROXYLATION; LIVER; MIXED FUNCTION OXYGENASES; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OXIDATION-REDUCTION; RECOMBINANT PROTEINS; SPECTROPHOTOMETRY, ULTRAVIOLET; STEROID 16-ALPHA-HYDROXYLASE; STEROID HYDROXYLASES; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; THIOPHENES; TICRYNAFEN;

FELIS CATUS;

EID: 0033564329     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9903289     Document Type: Article

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