Transforming growth factor-β1 modulates oxidatively modified LDL-induced expression of adhesion molecules: Role of LOX-1

Circulation Research

Volumn 89, Issue 12, 2001, Pages 1155-1160

  Chen, Hongjiang ^a   Li, Dayuan ^a   Saldeen, Tom ^b   Mehta, Jawahar L ^a,c  

^a CENTRAL ARKANSAS VETERANS HEALTHCARE SYSTEM   (United States)

^b UPPSALA UNIVERSITY   (Sweden)

^c UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Adhesion molecules; Endothelial cells; Oxidatively modified LDL; Transforming growth factor 1

Indexed keywords

CELL ADHESION MOLECULE; INTERCELLULAR ADHESION MOLECULE 1; IODINE 125; LOW DENSITY LIPOPROTEIN; MESSENGER RNA; PADGEM PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CELL ADHESION; CELL CULTURE; CONTROLLED STUDY; CORONARY ARTERY; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HUMAN; HUMAN CELL; MONOCYTE; PRIORITY JOURNAL;

EID: 0035824899     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/hh2401.100598     Document Type: Article

References (46)

1. Oxidative modification of LDL and atherogenesis
2. An endothelial receptor for oxidized low-density lipoprotein
3. Upregulation of endothelial receptor for oxidized LDL (LOX-1) by oxidized LDL and implications in apoptosis of human coronary artery endothelial cells: Evidence from use of antisense LOX-1 mRNA and chemical inhibitors
4. Oxidized LDL upregulates, angiotensin II type 1 receptor expression in cultured human coronary artery endothelial cells: The potential role of transcription factor NF-κB
5. The binding of oxidized low density lipoprotein (ox-LDL) to ox-LDL receptor-I reduces the intracellular concentration of nitric oxide in endothelial cells through an increased production of superoxide
6. Oxidized low density lipoprotein (ox-LDL) binding to ox-LDL receptor-1 in endothelial cells induces the activation of NF-κB through an increased production of intracellular reactive oxygen species
7. Expression of adhesion molecules by human endothelial cells exposed to oxidized low density lipoprotein: Influences of degree of oxidation and location of oxidized LDL
8. Antisense to LOX-1 inhibits oxidized LDL-mediated upregulation of monocyte chemoattractant protein-1 and monocyte adhesion to human coronary artery endothelial cells
9. Statins inhibit ox-LDL-induced expression of adhesion molecules and monocyte adhesion to human coronary endothelial cells: Role of mitogen-activated protein kinase and NF-κB
10. Atherosclerosis: An inflammatory disease
11. The combined role of P- and E-selectins in atherosclerosis
12. Direct demonstration of P-selectin- and VCAM-1-dependent mononuclear cell rolling in early atherosclerotic lesions of apolipoprotein E-deficient mice
13. Cytokine regulation of cellular adhesion molecule expression in inflammation
14. 3-mediated human endothelial cell adhesion and calcium signaling
15. Role of transforming growth factor-β1 in cardiovascular inflammatory changes induced by chronic inhibition of nitric oxide synthesis
16. 1 downregulates inflammatory cytokine-induced VCAM-1 expression in cultured human glomerular endothelial cells
17. TGF-β stimulation and inhibition of cell proliferation: New mechanistic insights
18. TGF-βs and TGF-β receptors in atherosclerosis
19. Role of transforming growth factor-β in human disease
20. TGF-β signal transduction
21. 1 excess as a mechanism for increased prevalence
22. Transforming growth factor-β inhibits human vascular smooth muscle cell growth and migration
23. 3-Hydroxy-3-methylglutaryl CoA reductase inhibitors up-regulate transforming growth factor-β signaling in cultured heart cells via inhibition of geranylgeranylation of RhoA GTPase
24. 1 reduce transplant arteriosclerosis: Insight derived from a knockout mouse model
25. The serum concentration of active transforming growth factor-β is severely depressed in advanced atherosclerosis
26. Altered plasma levels of cytokines in patients with ischemic heart disease
27. Serum levels of the TGF-β receptor are increased in atherosclerosis
28. Increased type II/type I TGF-β receptor ratio in cells derived from human atherosclerotic lesions: Conversion from an antiproliferative to profibrotic response to TGF-β1
29. 1 increases the expression of lectin-like oxidized low-density lipoprotein receptor-1
30. 1 downregulates CD36 and scavenger receptor A but upregulates LOX-1 in human macrophages
31. Role of TGF-β1 in platelet-mediated cardioprotection during ischemia-reperfusion in isolated rat hearts
32. Internalization of transforming growth factor-β and its receptor in BALB/c 3T3 fibroblasts
33. The insulin-like growth factor axis: A review of atherosclerosis and restenosis
34. Effect of human recombinant vascular endothelial growth factor 165 on progression of atherosclerotic plaque
35. Vascular endothelial growth factor enhances atherosclerotic plaque progression
36. 1 gene and protein expression associated with atherogenesis of cholesterol-fed rabbits
37. Activation of transforming growth factor-β is inhibited in transgenic apolipoprotein(a) mice
38. Potential mechanisms for the plasmin-mediated release and activation of latent transforming growth factor-β1 from the extracellular matrix of growth plate chondrocytes
39. Feedback mechanism of focal vascular lesion formation in transgenic apolipoprotein(a) mice
40. Angiotensin-II via ATI receptor activation upregulates endoglin expression in human coronary artery endothelial cells
41. Transforming growth factor-β1 decreases cholesterol supply to mitochondria via repression of steroidogenic acute regulatory protein expression
42. TGF-β reduced binding of high-density lipoproteins in murine macrophages and macrophage-derived foam cells
43. 1 in feline myocardial ischemia and reperfusion
44. Endoglin is overexpressed after arterial injury and is required for transforming growth factor-β-induced inhibition of smooth muscle cell migration
45. Elevated expression of endoglin, a component of the TGF-β-receptor complex, correlates with proliferation of tumor endothelial cells
46. Endoglin overexpression modulates cellular morphology, migration, and adhesion of mouse fibroblasts