Novel monoclonal antibodies against proteolipid protein peptide 139-151 demonstrate demyelination and myelin uptake by macrophages in MS and marmoset EAE lesions

Journal of Neuroimmunology

Volumn 119, Issue 1, 2001, Pages 124-130

  Laman, Jon D ^a   Visser, Lizette ^a   Maassen, Catharina B M ^a,b   De Groot, Corline J A ^c   De Jong, Laurina A ^b   'T Hart, Bert A ^d   Van Meurs, Marjan ^a   Schellekens, Marc M ^b  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b TNO   (Netherlands)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^d BIOMEDICAL PRIMATE RESEARCH CENTRE   (Netherlands)

Author keywords

Animal model; Axonal loss; Demyelination; Immunohistochemistry; Lesional staging; Multiple sclerosis (MS)

Indexed keywords

CD4 ANTIGEN; EPITOPE; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN G2B; MONOCLONAL ANTIBODY; MYELIN; PARAFFIN; PROTEOLIPID PROTEIN; PROTEOLIPID PROTEIN[139-151]; UNCLASSIFIED DRUG;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ANTIGEN EXPRESSION; ARTICLE; BRAIN REGION; CONTROLLED STUDY; CYTOPLASM; DEMYELINATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FROZEN SECTION; HYBRIDOMA; IMMUNIZATION; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MACROPHAGE; MONKEY; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; TH1 CELL;

ANIMALS; ANTIBODIES, MONOCLONAL; CALLITHRIX; DEMYELINATING DISEASES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; HUMANS; MACROPHAGES; MICE; MICE, INBRED STRAINS; MULTIPLE SCLEROSIS; MYELIN PROTEOLIPID PROTEIN; MYELIN SHEATH; PEPTIDE FRAGMENTS; REFERENCE VALUES;

EID: 0035801801     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(01)00356-3     Document Type: Article

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