Neuronal death and GSK-3β: A tau fetish?

Trends in Neurosciences

Volumn 24, Issue 5, 2001, Pages 255-256

  Mattson, Mark P ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; AXIN; CELL ADHESION MOLECULE; CYCLIN D1; GLYCOGEN SYNTHASE KINASE 3BETA; GUANINE NUCLEOTIDE EXCHANGE FACTOR; HEAT SHOCK TRANSCRIPTION FACTOR 1; INSULIN; INTEGRIN; NEUROTROPHIN; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PRESENILIN 1; PYRUVATE DEHYDROGENASE; SOMATOMEDIN; TAU PROTEIN; TETRACYCLINE;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; CELL DEATH; CELL SURVIVAL; CHROMOSOME 17; CONTROLLED STUDY; DEGENERATIVE DISEASE; DENTATE GYRUS; DRUG INDUCED DISEASE; EMBRYO DEVELOPMENT; ENERGY METABOLISM; EXTRACELLULAR MATRIX; FRONTOTEMPORAL DEMENTIA; GENE OVEREXPRESSION; HIPPOCAMPUS; HUMAN; IN VIVO STUDY; MOUSE; NERVE CELL DEGENERATION; NERVE FIBER; NONHUMAN; NOTE; PARKINSONISM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSACTIVATION;

EID: 0035341370     PISSN: 01662236     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-2236(00)01838-5     Document Type: Short Survey

References (3)

1. Decreased nuclear β-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3β conditional transgenic mice
2. Glycogen synthase kinase-3β phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice
3. Integrin signaling via the PI3 kinase - Akt pathway increases neuronal resistance to glutamate-induced apoptosis