Netrin signal is produced in leech embryos by segmentally iterated sets of central neurons and longitudinal muscle cells

Development Genes and Evolution

Volumn 211, Issue 12, 2001, Pages 589-596

  Aisemberg, G ^a,c   Kuhn, J ^b,c   Macagno, E ^b,c  

^a CITY UNIVERSITY OF NEW YORK   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Axon; Embryo; Leech; Netrin; Neuron

Indexed keywords

ANTIGEN; MONOCLONAL ANTIBODY; NETRIN; PROTEIN; PROTEIN ANTIBODY; RECEPTOR;

ANTIGEN EXPRESSION; ARTICLE; CELL POLARITY; CELL SECRETION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DEVELOPMENTAL BIOLOGY; EMBRYO; EMBRYO SEGMENTATION; LEECH; MOLECULAR CLONING; MUSCLE CELL; NERVE CELL; NERVE FIBER GROWTH; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; SIGNAL TRANSDUCTION; STAINING;

ANIMALS; EMBRYO, NONMAMMALIAN; GANGLIA, INVERTEBRATE; INTERNEURONS; LEECHES; MUSCLE FIBERS; NERVE GROWTH FACTORS; NEURONS; SIGNAL TRANSDUCTION;

ANIMALIA; HIRUDINIDA;

EID: 0035709657     PISSN: 0949944X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00427-001-0183-2     Document Type: Article

References (49)

1. The mouse rostral cerebellar malformation gene encodes an UNC-5-like protein
2. Evidence for a clade of nematodes, arthropods and other moulting animals
3. Lox1, an Antennapedia-class homeobox gene, is expressed during leech gangliogenesis in both transient and stable central neurons
4. Comparison of early nerve cord development in insects and vertebrates
5. The specificity of 130-kDa leech sensory afferent proteins is encoded by their carbohydrate epitopes
6. RNAi of the receptor tyrosine phosphatase HmLar2 in a single cell of an intact leech embryo leads to growth cone collapse
7. Neurobiology and development of the leech
8. Slit proteins bind robo receptors and have an evolutionarily conserved role in repulsive axon guidance
9. UNC-40, a C. elegans homolog of DCC (Deleted in Colorectal Cancer) is required in motile cells responding to UNC-6 netrin cues
10. The axonal chemoattractant netrin-1 is also a chemorepellent for trochlear motor axons
11. Embryonic development of the hirudinid leech Hirudo medicinalis: Structure, development and segmentation of the germinal plate
12. A multi somatic axon in the central nervous system of the leech
13. Cellular expression of a leech netrin suggests roles in the formation of longitudinal nerve tracts and in regional innervation of peripheral targets
14. Evidence from 18S ribosomal DNA that the lophophorates are protostome animals
15. Expression of the unc-5 guidance receptor in the touch neurons of C. elegans steers their axons dorsally
16. Guidance cues at the Drosophila CNS midline: Identification and characterization of two Drosophila netrin/UNC-6 homologs
17. The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans
18. The Drosophila netrin receptor Frazzled guides axons by controlling Netrin distribution
19. Growth-cone attraction to netrin-1 is converted to repulsion by laminin-1
20. Differential glycosylation of tractin and LeechCAM, two novel Ig superfamily members, regulates neurite extension and fascicle formation
21. UNC-6, a laminin related protein, guides pioneer axon migrations in C. elegans
22. Posttranslational processing and differential glycosylation of Tractin, an Ig-superfamily member involved in regulation of axonal outgrowth
23. Deleted in Colorectal Cancer (DCC) encodes a netrin receptor
24. Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord
25. Slit is the midline repellent for the robo receptor in Drosophila
26. Frazzled encodes a Drosophila member of the DCC immunoglobulin subfamily and is required for CNS and motor axon guidance
27. Axon tracts correlate with netrin-la expression in the zebrafish embryo
28. Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors
29. Segmentation and segmental differentiation in the development of the central nervous systems of leeches and flies
30. Vertebrate slit, a secreted ligand for the transmembrane protein roundabout, is a repellent for olfactory bulb axons
31. Number and distribution of neurons in leech segmental ganglia
32. Cell death during gangliogenesis in the leech: Competition leading to the death of PMS neurons has both random and nonrandom components
33. Neuronal competition determines the spatial pattern of neuropeptide expression by identified neurons of the leech
34. Expression of surface glycoproteins early in leech neural development
35. Genetic analysis of netrin genes in Drosophila: Netrins guide CNS commissural axons and peripheral motor neurons
36. Correct axonal regeneration after target cell removal in the central nervous system of the leech
37. La rétine des vertébrés
38. Hox genes in brachiopods and priapulids and protostome evolution
39. The S cell: An interneuron essential for sensitization and full dishabituation of leech shortening
40. The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6
41. Netrin is required for commissural axon guidance in the developing vertebrate nervous system
42. Segmental specificity and lateral asymmetry in the differentiation of segmentally homologous neurons during leech embryogenesis
43. Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase
44. Segmental differentiation in the leech nervous system: The genesis of cell number in the segmental ganglia of Haemopis marmorata
45. Cell death during gangliogenesis in the leech: Bipolar cells appear and then degenerate in all ganglia
46. Regulation of the UNC-5 netrin receptor initiates the first reorientation of migrating distal tip cells in Caenorhabditis elegans
47. The segmentation of the leech nervous system is prefigured by myogenic cells at the embryonic midline expressing a muscle-specific matrix protein
48. Genetic analysis of the mechanisms controlling target selection: And combinatorial functions of netrins, semaphorins, and IgCAMs