Genetic analysis of dPsa, the Drosophila orthologue of puromycin-sensitive aminopeptidase, suggests redundancy of aminopeptidases

Development Genes and Evolution

Volumn 211, Issue 12, 2001, Pages 581-588

  Schulz, Cordula ^a,b   Perezgasga, Lucia ^a,b   Fuller, Margaret T ^a,b  

^a STANFORD UNIVERSITY   (United States)

^b INSTITUTO DE BIOTECNOLOGÍA   (Mexico)

Author keywords

Genetic redundancy; Mutant; Overexpression; Protein degradation; Spermatogenesis

Indexed keywords

AMINOPEPTIDASE; PUROMYCIN;

AMINO ACID SEQUENCE; ANTIBIOTIC SENSITIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DROSOPHILA; EMBRYO DEVELOPMENT; GENE ACTIVITY; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE OVEREXPRESSION; GENETIC ANALYSIS; GENETIC SCREENING; HUMAN; INSECT DEVELOPMENT; LARVAL DEVELOPMENT; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ORTHOLOGY; PHYLOGENETIC TREE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; TISSUE DISTRIBUTION;

AMINO ACID SEQUENCE; AMINOPEPTIDASES; ANIMALS; DROSOPHILA; FEMALE; HUMANS; MALE; MOLECULAR SEQUENCE DATA; ORGAN SPECIFICITY; OVARY; SEQUENCE ALIGNMENT; TESTIS;

ANIMALIA; ARACHNIDA; HEXAPODA; INSECTA; MAMMALIA;

EID: 0035709639     PISSN: 0949944X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00427-001-0194-z     Document Type: Article

References (52)

1. Changes in aminopeptidase N located on neutrophils derived from patients with chronic pain
2. Basic local alignment search tool
3. Regulation of proteolysis
4. Proteolysis that is inhibited by hedgehog targets cubitus interruptus protein to the nucleus and converts it to a repressor
5. The embryonic development of Drosophila melanogaster
6. The ubiquitin-proteasome proteolytic pathway
7. Puromycin-sensitive aminopeptidase. Sequence analysis, expression, and functional characterization
8. Aminopeptidase-N (CD13; gp 150): Contrasting patterns of enzymatic activity in blood from patients with myeloid or lymphoid leukemia
9. The FlyBase database of the Drosophila genome projects and community literature
10. Proteolysis, proteasomes and antigen presentation
11. An aminopeptidase from bovine brain which catalyzes the hydrolysis of enkephalin
12. Changes in puromycin-sensitive aminopeptidase in postmortem schizophrenic brain regions
13. Regulation of runt transcription by Drosophila segmentation genes
14. How the cyclin became a cyclin: Regulated proteolysis in the cell cycle
15. Reduction of plasma glutamyl aminopeptidase activity in sporadic Alzheimer's disease
16. The Bearded box, a novel 3' UTR sequence motif, mediates negative post-transcriptional regulation of Bearded and Enhancer of split Complex gene expression
17. Characterization of three aminopeptidases purified from maternal serum
18. Modulation of WNT-5A expression by actinonin: Linkage of APN to the WNT-pathway?
19. Studies on the tissue distribution of the puromycin-sensitive enkephalindegrading aminopeptidases
20. Carboxylesterases moonlight in the male reproductive tract: A functional shift pivotal for male fertility
21. Redundancy as a way of life - IAA metabolism
22. Evolution of genetic redundancy
23. Increased anxiety and impaired pain response in puromycin-sensitive aminopeptidase gene-deficient mice obtained by a mouse gene-trap method
24. Male reproductive defects caused by puromycin-sensitive aminopeptidase deficiency in mice
25. Puromycin-sensitive aminopeptidase is essential for the maternal recognition of pregnancy in mice
26. TreeView: An application to display phylogenetic trees on personal computers
27. Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis
28. Ectopic gene expression in Drosophila using GAL4 system
29. The bdr families of the Lyme disease and relapsing fever spirochetes: Potential influence on biology, pathogenesis and evolution
30. Peptidase activities in Saccharomyces cerevisiae
31. Drosophila development: The secrets of delayed induction
32. Degradation of dynorphin-related peptides by the puromycin-sensitive aminopeptidase and amino-peptidase M
33. Human aminopeptidase: A review of the literature
34. Induction of apoptosis by bestatin (ubenimex) in human leukemic cell lines
35. P-element mediated transformation
36. Two new proteases in the MHC class I processing pathway
37. Redundancies, development and the flow of information
38. A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback
39. Aminopeptidases: Towards a mechanism of action
40. Aminopeptidases: Structure and function
41. The Arabidopsis Genome Initiative Analysis of the genome sequence of the flowering plant Arabidopsis thaliana
42. The Clustalwindows interface: Flexible strategies for multiple sequence alignment aided by quality analysis tools
43. 4 hydrolyse, a bifunctional enzyme in inflammation
44. Cloning of the human puromycin-sensitive aminopeptidase and evidence for expression in neurons
45. The calmodulin multigene family as a unique case of genetic redundancy: Multiple levels of regulation to provide spatial and temporal control of calmodulin pools?
46. Robustness against mutations in genetic networks of yeast
47. Structure and mechanism of a proline-specific aminopeptidase from Escherichia coli
48. Giant proteases: Beyond the proteasome
49. The cell cycle and development: Redundant roles of cell cycle regulators
50. Efficient and dispersed local P element transposition from Drosophila females