Cloning of the human puromycin-sensitive aminopeptidase and evidence for expression in neurons

Journal of Neurochemistry

Volumn 68, Issue 3, 1997, Pages 889-897

  Tobler, A R ^a,c   Constam, D B ^a,d   Schmitt Graff A ^b   Malipiero, U ^a   Schlapbach, R ^a   Fontana, A ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d HARVARD UNIVERSITY   (United States)

Author keywords

Amino peptidase; Apoptosis; Enkephalinase; Neurons; Puromycin

Indexed keywords

AMINOPEPTIDASE; PUROMYCIN;

ARTICLE; BLOOD VESSEL; BRAIN NERVE CELL; CYTOPLASM; DNA LIBRARY; GLIA CELL; HELA CELL; HUMAN; HUMAN CELL; IN SITU HYBRIDIZATION; MOLECULAR CLONING; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA TRANSLATION; START CODON; VESICULAR STOMATITIS VIRUS;

VESICULAR STOMATITIS VIRUS;

EID: 0031028814     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1997.68030889.x     Document Type: Article

References (36)

1. Aslanidis C. and De Jong J. P. (1990) Ligation-independent cloning of PCR products (LIC-PCR). Nucleic Acids Res. 18, 6069-6074.
2. Bausback H. H., Churchill L., and Ward P. E. (1988) Angiotensin metabolism by cerebral microvascular aminopeptidase A. Biochem. Pharmacol. 37, 155-160.
3. Chang Y. H. and Smith J. A. (1989) Molecular cloning and sequencing of genomic DNA encoding aminopeptidase I from Saccharomyces cerevisiae. J. Biol. Chem. 264, 6979-6983.
4. Constam D. B., Tobler A. R., Rensing E. A., Kemler I., Hersh L. B., and Fontana A. (1995) Puromycin-sensitive aminopeptidase. Sequence analysis, expression, and functional characterization. J. Biol. Chem. 270, 26931-26939.
5. Davidoff A. N. and Mendelow B. V. (1993) Puromycin-elicited c-myc mRNA superinduction precedes apoptosis in HL-60 leukaemic cells. Anticancer Res. 13, 2257-2260.
6. De La Baume S., Yi C. C., Schwartz J. C., Chaillet P., Marcais C. H., and Costentin J. (1983) Participation of both 'enkephalinase' and aminopeptidase activities in the metabolism of endogenous enkephalins. Neuroscience 8, 143-151.
7. Dyer S. H., Slaughter C. A., Orth K., Moomaw C. R., and Hersh L. B. (1990) Comparison of the soluble and membrane-bound forms of the puromycin-sensitive enkephalin-degrading aminopeptidases from rat. J. Neurochem. 54, 547-554.
8. Gallione C. J. and Rose J. K. (1985) A single amino acid substitution in a hydrophobic domain causes temperature-sensitive cell-surface transport of a mutant viral glycoprotein. J. Virol. 54, 374-382.
9. Gros C., Giros B., and Schwartz J. C. (1985) Identification of aminopeptidase M as an enkephalin-inactivating enzyme in rat cerebral membranes. Biochemistry 24, 2179-2185.
10. Haun R. S., Serventi I. M., and Moss J. (1992) Rapid, reliable ligation-independent cloning of PCR products using modified plasmid vectors. Biotechniques 13, 515-518.
11. Herbst H., Heinrichs O., Schuppan D., Milani S., and Stein H. (1991) Temporal and spatial patterns of transin/stromelysin RNA expression following toxic injury in rat liver. Virchows Arch. [B] 60, 295-300.
12. Herman Z. S., Stachura Z., Laskawiec G., Kowalski J., and Obuchowicz E. (1985) Antinociceptive effects of puromycin and bacitracin. Pol. J. Pharmacol. Pharm. 37, 133-140.
13. Hersh L. B. (1985) Characterization of membrane-bound aminopeptidases from rat brain: identification of the enkephalin-degrading aminopeptidase. J. Neurochem. 44, 1427-1435.
14. Hersh L. B., Aboukhair N., and Watson S. (1987) Immunohistochemical localization of aminopeptidase M in rat brain and periphery: relationship of enzyme localization and enkephalin metabolism. Peptides 8, 523-532.
15. Hooper N. M. (1994) Families of zinc metalloproteases. FEBS Lett. 354, 1-6.
16. Hui K. S., Wang Y. J., and Lajtha A. (1983) Purification and characterization of an enkephalin aminopeptidase from rat brain membranes. Biochemistry 22, 1062-1067.
17. Hui K. S., Hui M. P., and Lajtha A. (1988) Major rat brain membrane-associated and cytosolic enkephalin-degrading aminopeptidases: comparison studies. J. Neurosci. Res. 20, 231-240.
18. Hui K. S., Hui M., Lajtha A., Saito M., and Saito M. (1990) Cellular localization of puromycin-sensitive aminopeptidase isozymes. Neurochem. Res. 15, 1147-1151.
19. Hui K. S., Saito M., Hui M., Saito M., Lajtha A., Yamamoto K., and Osawa T. (1993) Two cytosolic puromycin-sensitive aminopeptidase isozymes in chicken brain: molecular homology to brain-specific 14-3-3 protein. Neurochem. Int. 22, 445-453.
20. Hui M. P., Lajtha A., and Hui K. S. (1993) A new soluble brain-specific protein: identification and partial purification. Brain Res. 606, 36-43.
21. Kerr M. A. and Kenny A. J. (1974) The purification and specificity of a neutral endopeptidase from rabbit kidney brush border. Biochem. J. 137, 477-488.
22. Kozak M. (1991) Structural features in eukaryotic mRNAs that modulate the initiation of translation. J. Biol. Chem. 266, 19867-19870.
23. Kreis T. E. (1986) Microinjected antibodies against the cytoplasmic domain of vesicular stomatitis virus glycoprotein block its transport to the cell surface. EMBO J. 5, 931-941.
24. Malfroy B., Swerts J. P., Guyon A., Roques B. P., and Schwartz J. C. (1978) High-affinity enkephalin-degrading peptidase in brain is increased after morphine. Nature 276, 523-526.
25. Matsas R., Stephenson S. L., Hryszko J., Kenny A. J., and Turner A. J. (1985) The metabolism of neuropeptides. Phase separation of synaptic membrane preparations with Triton X-114 reveals the presence of aminopeptidase N. Biochem. J. 231, 445-449.
26. McDermott J. R., Mantle D., Lauffart B., and Kidd A. M. (1985) Purification and characterization of a neuropeptide-degrading aminopeptidase from human brain. J. Neurochem. 45, 752-759.
27. McKelvy J. F. and Blumberg S. (1986) Inactivation and metabolism of neuropeptides. Annu. Rev. Neurosci. 9, 415-434.
28. McLellan S., Dyer S. H., Rodriguez G., and Hersh L. B. (1988) Studies on the tissue distribution of the puromycin-sensitive enkephalin-degrading aminopeptidases. J. Neurochem. 51, 1552-1559.
29. Milani S., Herbst H., Schuppan D., Grappone C., Pellegrini G., Pinzani M., Casini A., Calabro A., Ciancio G., Stefanini F., Burroughs A. K., and Surrenti C. (1994) Differential expression of matrix-metalloproteinase-1 and -2 genes in normal and fibrotic human liver. Am. J. Pathol. 144, 528-537.
30. Schnebli H. P., Phillipps M. A., and Barclay R. K. (1979) Isolation and characterization of an enkephalin-degrading aminopeptidase from rat brain. Biochim. Biophys. Acta 569, 89-98.
31. Stein H., Gatter K., Asbahr H., and Mason D. Y. (1985) Use of freeze-dried paraffin-embedded sections for immunohistologic staining with monoclonal antibodies. Lab. Invest. 52, 676-683.
32. Taylor A. (1993a) Aminopeptidases: towards a mechanism of action. Trends Biochem. Sci. 18, 167-171.
33. Taylor A. (1993b) Aminopeptidases: structure and function. FASEB J. 7, 290-298.
34. Turner A. J., Hooper N. M., and Kenny A. J. (1989) Chapter 3, in Neuropeptides: A Methodology (Fink G. and Harmar A. J., eds), pp. 120-127. John Wiley & Sons, New York.
35. Ulrich C. and Hersh L. B. (1985) Degradation of alpha and beta neo-endorphin by rat brain membrane peptidases. Peptides 6, 475-482.
36. Zhang A. Z., Yang H. Y., and Costa E. (1982) Nociception, enkephalin content and dipeptidyl carboxypeptidase activity in brain of mice treated with exopeptidase inhibitors. Neuropharmacology 21, 625-630.