Recent developments in computational proteomics

Drug Discovery Today

Volumn 6, Issue 19, 2001, Pages 996-1004

  Maggio, Edward T ^a   Ramnarayan, Kal ^a  

^a Structural Bioinformatics Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG; PROTEIN; PROTEINASE; RNA DIRECTED DNA POLYMERASE;

COMPUTER ANALYSIS; CRYSTAL STRUCTURE; DATA BASE; DRUG DEVELOPMENT; GENOME; HUMAN IMMUNODEFICIENCY VIRUS; MODEL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHARMACOGENETICS; PREDICTION; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REVIEW; X RAY CRYSTALLOGRAPHY;

EID: 0035479080     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-6446(01)02003-7     Document Type: Review

References (30)

1. The sequence of the human genome
2. Initial sequencing and analysis of the human genome
3. Structural genomics programs at the US National Institute of General Medical Sciences
4. Structural genomics in North America
5. Structural genomics projects in Japan
6. Structural genomics in Europe: slow start, strong finish?
7. The Protein Data Bank
8. Threading with explicit models for evolutionary conservation of structure and sequence
9. MBO(N)D: a multibody method for long-time molecular dynamics simulations
10. The crystal structure of an engineered monomeric triosephosphate isomerase, monoTIM: the correct modeling of an eight-residue loop
11. A method to configure protein side-chains from the main-chain trace in homology modelling
12. Modeling side-chain conformation
13. Protein structure prediction using a combination of sequence homology and global energy minimization: II. Energy functions
14. Conformational parameters for amino acids in helical, β-sheet, and random coil regions calculated from proteins
15. Analysis and implications of simple methods for predicting the secondary structure of globular proteins
16. Prediction of protein secondary structure at better than 70% accuracy
17. SOPMA: significant improvements in protein secondary structure prediction by consensus predictions from multiple alignments
18. Seventy-five percent accuracy in protein secondary structure prediction
19. Evaluation and improvement of multiple sequence methods for protein secondary structure prediction
20. New methods for accurate prediction of protein secondary structure
21. Protein secondary structure prediction based on position-specific scoring matrices
22. Protein secondary structure prediction at 80% accuracy
23. Protein folding and wring resonances
24. From genes to protein structure and function: novel applications of computational approaches in the genomic era
25. A new approach to protein fold recognition
26. Protein structure prediction by threading methods: evaluation of current techniques