Functional and molecular analysis of hematopoietic progenitors derived from the aorta-gonad-mesonephros region of the mouse embryo

Blood

Volumn 94, Issue 5, 1999, Pages 1495-1503

  Delassus, Sylvie ^a   Titley, Ian ^a   Enver, Tariq ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLOBIN; CD3 ANTIGEN; CD34 ANTIGEN; COLONY STIMULATING FACTOR RECEPTOR; GRANULOCYTE COLONY STIMULATING FACTOR; MYELOPEROXIDASE; STEM CELL FACTOR; THY 1 ANTIGEN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANTIGEN EXPRESSION; AORTA; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; ERYTHROID CELL; FEMALE; GENE ACTIVATION; GONAD; HEMATOPOIETIC STEM CELL; MESONEPHROS; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION;

EID: 0033199330     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v94.5.1495.417a08_1495_1503     Document Type: Article

References (50)

1. Dzierzak E, Sanchez MJ, Muller A, Miles C, Holmes A, Tidcombe H, Medvinsky A: Hematopoietic stem cells: Embryonic beginnings. J Cell Physiol 173:216, 1997
2. Robb L: Hematopoiesis: Origin pinned down at last? Curr Biol 7:R10, 1997
3. Mukouyama Y, Hara T, Xu M, Tamura K, Donovan PJ, Kim H, Kogo H, Tsuji K, Nakahata T, Miyajima A: In vitro expansion of murine multipotential hematopoietic progenitors from the embryonic aortagonad-mesonephros region. Immunity 8:105, 1998
4. Muller AM, Medvinsky A, Strouboulis J, Grosveld F, Dzierzak E: Development of hematopoietic stem cell activity in the mouse embryo. Immunity 1:291, 1994
5. Yoder MC, Hiatt K, Mukherjee P: In vivo repopulating hematopoietic stem cells are present in the murine yolk sac at day 9.0 postcoitus. Proc Natl Acad Sci USA 94:6776, 1997
6. Sanchez MJ, Holmes A, Miles C, Dzierzak E: Characterization of the first definitive hematopoietic stem cells in the AGM and liver of the mouse embryo. Immunity 5:513, 1996
7. Yoder MC, Hiatt K, Dutt P, Mukherjee P, Bodine DM, Orlic D: Characterization of definitive lymphohematopoietic stem cells in the day 9 murine yolk sac. Immunity 7:335, 1997
8. Peault B: Hematopoietic stem cell emergence in embryonic life: Developmental hematology revisited. J Hematother 5:369, 1996
9. + hematopoietic cells in the early human embryo. Blood 87:67, 1996
10. Wood HB, May G, Healy L, Enver T, Morriss-Kay GM: CD34 expression patterns during early mouse development are related to modes of blood vessel formation and reveal additional sites of hematopoiesis. Blood 90:2300, 1997
11. Yoder MC, Hiatt K: Engraftment of embryonic hematopoietic cells in conditioned newborn recipients. Blood 89:2176, 1997
12. Enver T, Greaves M: Loops, lineage, and leukemia. Cell 94:9, 1998
13. Cumano A, Dorshkind K, Gillis S, Paige CJ: The influence of S17 stromal cells and interleukin 7 on B cell development. Eur J Immunol 20:2183, 1990
14. Forni L: Reagents for immunofluorescence and their use for studying lymphoid cell products, in Pernis I (ed): Immunological Methods, vol 151. New York, NY, Academic, 1979
15. Delassus S, Cumano A: Circulation of hematopoietic progenitors in the mouse embryo. Immunity 4:97, 1996
16. Dexter TM, Garland J, Scott D, Scolnick E, Metcalf D: Growth of factor-dependent hemopoietic precursor cell lines. J Exp Med 152:1036, 1980
17. Hu M, Krause D, Greaves M, Sharkis S, Dexter M, Heyworth C, Enver T: Multilineage gene expression precedes commitment in the hemopoietic system. Genes Dev 11:774, 1997
18. Brown J, Greaves MF, Molgaard HV: The gene encoding the stem cell antigen, CD34, is conserved in mouse and expressed in haemopoietic progenitor cell lines, brain, and embryonic fibroblasts. Int Immunol 3:175, 1991
19. Qiu FH, Ray P, Brown K, Barker PE, Jhanwar S, Ruddle FH, Besmer P: Primary structure of c-kit: Relationship with the CSF-1/ PDGF receptor kinase family - Oncogenic activation of v-kit involves deletion of extracellular domain and C terminus. EMBO J 7:1003, 1988
20. D'Andrea AD, Fasman GD, Lodish HF: Erythropoietin receptor and interleukin-2 receptor beta chain: A new receptor family. Cell 58:1023, 1989
21. Fukunaga R, Ishizaka-Ikeda E, Seto Y, Nagata S: Expression cloning of a receptor for murine granulocyte colony-stimulating factor. Cell 61:341, 1990
22. Venturelli D, Bittenbender S, Rovera G: Sequence of the murine myeloperoxidase (MPO) gene. Nucleic Acids Res 17:7987, 1989
23. Shehee WR, Loeb DD, Adey NB, Burton FH, Casavant NC, Cole P, Davies CJ, McGraw RA, Schichman SA, Severynse DM, Voliva F, Weyter FW, Wisely GB, Edgell MH, Hutchison CA III: Nucleotide sequence of the BALB/c mouse beta-globin complex. J Mol Biol 205:41, 1989
24. Kudo A, Sakaguchi N, Melchers F: Organization of the murine Ig-related lambda 5 gene transcribed selectively in pre-B lymphocytes [published erratum appears in EMBO J 6:4242, 1987]. EMBO J 6:103, 1987
25. Godin I, Dieterlen-Lievre F, Cumano A: Emergence of multipotent hemopoietic cells in the yolk sac and paraaortic splanchnopleura in mouse embryos, beginning at 8.5 days postcoitus [published erratum appears in Proc Natl Acad Sci USA 92:10815, 1995]. Proc Natl Acad Sci USA 92:773, 1995
26. Cumano A, Paige CJ: Enrichment and characterization of uncommitted B-cell precursors from fetal liver at day 12 of gestation. EMBO J 11:593, 1992
27. Haynes BF, Denning SM, Singer KH, Kurtzberg J: Ontogeny of T-cell precursors: A model for the initial stages of human T-cell development. Immunol Today 10:87, 1989
28. Shivdasani RA, Orkin SH: The transcriptional control of hematopoiesis. Blood 87:4025, 1996
29. Okuda T, van Deursen J, Hiebert SW, Grosveld G, Downing JR: AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis. Cell 84:321, 1996
30. Scott EW, Simon MC, Anastasi J, Singh H: Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages. Science 265: 1573, 1994
31. Tsai FY, Orkin SH: Transcription factor GATA-2 is required for proliferation/survival of early hematopoietic cells and mast cell formation, but not for erythroid and myeloid terminal differentiation. Blood 89:3636, 1997
32. Tsai FY, Keller G, Kuo FC, Weiss M, Chen J, Rosenblatt M, Alt FW, Orkin SH: An early haematopoietic defect in mice lacking the transcription factor GATA-2. Nature 371:221, 1994
33. Tenen DG, Hromas R, Licht JD, Zhang DE: Transcription factors, normal myeloid development, and leukemia. Blood 90:489, 1997
34. Brady G, Barbara M, Iscove NN: Representative in vitro cDNA amplification from individual hemopoietic cells and colonies. Methods Mol Cell Biol 2:17, 1990
35. Ford AM, Healy LE, Bennett CA, Navarro E, Spooncer E, Greaves MF: Multilineage phenotypes of interleukin-3-dependent progenitor cells. Blood 79:1962, 1992
36. + cells are the only stem cells in C57BL/Ka-Thy-1.1 bone marrow. J Exp Med 175:175, 1992
37. Vidal M, Morris R, Grosveld F, Spanopoulou E: Tissue-specific control elements of the Thy-1 gene. EMBO J 9:833, 1990
38. Pillai S, Baltimore D: Formation of disulphide-linked mu 2 omega 2 tetramers in pre-B cells by the 18K omega-immunoglobulin light chain. Nature 329:172, 1987
39. Sakaguchi N, Melchers F: Lambda 5, a new light-chain-related locus selectively expressed in pre-B lymphocytes. Nature 324:579, 1986
40. Medvinsky A, Dzierzak E: Definitive hematopoiesis is autonomously initiated by the AGM region. Cell 86:897, 1996
41. Medvinsky AL, Samoylina NL, Muller AM, Dzierzak EA: An early pre-liver intraembryonic source of CFU-S in the developing mouse. Nature 364:64, 1993
42. Ford AM, Bennett CA, Healy LE, Towatari M, Greaves MF, Enver T: Regulation of the myeloperoxidase enhancer binding proteins Pul, C-EBP-alpha, -beta, and -delta during granulocyte-lineage specification. Proc Natl Acad Sci USA 93:10838, 1996
43. Crotta S, Nicolis S, Ronchi A, Ottolenghi S, Ruzzi L, Shimada Y, Migliaccio AR, Migliaccio G: Progressive inactivation of the expression of an erythroid transcriptional factor in GM- and G-CSF-dependent myeloid cell lines. Nucleic Acids Res 18:6863, 1990
44. Zhu J, Bennett CA, MacGregor AD, Greaves MF, Goodwin GH, Ford AM: A myeloid-lineage-specific enhancer upstream of the mouse myeloperoxidase (MPO) gene. Leukemia 8:717, 1994
45. Heberlein C, Fischer KD, Stoffel M, Nowock J, Ford A, Tessmer U, Stocking C: The gene for erythropoietin receptor is expressed in multipotential hematopoietic and embryonal stem cells: Evidence for differentiation stage-specific regulation. Mol Cell Biol 12:1815, 1992
46. Jimenez G, Griffiths SD, Ford AM, Greaves MF, Enver T: Activation of the beta-globin locus control region precedes commitment to the erythroid lineage. Proc Natl Acad Sci USA 89:10618, 1992
47. Greaves MF, Chan LC, Furley AJ, Watt SM, Molgaard HV: Lineage promiscuity in hemopoietic differentiation and leukemia. Blood 67:1, 1986
48. Ashe HL, Monks J, Wijgerde M, Fraser P, Proudfoot NJ: Intergenic transcription and transinduction of the human beta-globin locus. Genes Dev 11:2494, 1997
49. Ford AM, Bennett CA, Healy LE, Navarro E, Spooncer E, Greaves MF: Immunoglobulin heavy-chain and CD3 delta-chain gene enhancers are DNase I-hypersensitive in hemopoietic progenitor cells. Proc Natl Acad Sci USA 89:3424, 1992
50. Wang H, Diamond RA, Rothenberg EV: Cross-lineage expression of Ig-beta (B29) in thymocytes: Positive and negative gene regulation to establish T cell identity. Proc Natl Acad Sci USA 95:6831, 1998