메뉴 건너뛰기




Volumn 17, Issue 4, 2001, Pages 199-205

What regulates mitochondrial DNA copy number in animal cells?

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED DNA POLYMERASE GAMMA; MITOCHONDRIAL DNA; PRIMER RNA; RNA POLYMERASE; THYROID HORMONE; TRANSCRIPTION FACTOR;

EID: 0035313402     PISSN: 01689525     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-9525(01)02238-7     Document Type: Review
Times cited : (245)

References (60)
  • 1
    • 0034603852 scopus 로고    scopus 로고
    • New features of mitochondrial DNA replication system in yeast and man
    • (2000) Gene , vol.246 , pp. 37-48
    • Lecrenier, N.1    Foury, F.2
  • 2
    • 0023442326 scopus 로고
    • Isolation of morphologically intact mitochondrial nucleoids from the yeast, Saccharomyces cerevisiae
    • (1987) J. Cell Sci. , vol.88 , pp. 431-439
    • Miyakawa, I.1
  • 4
    • 0029060751 scopus 로고
    • A role for recombination junctions in the segregation of mitochondrial DNA in yeast
    • (1995) Cell , vol.81 , pp. 947-955
    • Lockshon, D.1
  • 5
    • 0344004866 scopus 로고    scopus 로고
    • Mgm101p is a novel component of the mitochondrial nucleoid that binds DNA and is required for the repair of oxidatively damaged mitochondrial DNA
    • (1999) J. Cell Biol. , vol.145 , pp. 291-304
    • Meeusen, S.1
  • 6
    • 0031943922 scopus 로고    scopus 로고
    • Functions of the high mobility group protein, Abf2p, in mitochondrial DNA segregation, recombination and copy number in Saccharomyces cerevisiae
    • (1998) Genetics , vol.148 , pp. 1763-1776
    • Zelenaya-Troitskaya, O.1
  • 7
    • 0034121640 scopus 로고    scopus 로고
    • No sex please, we're mitochondria: A hypothesis on the somatic unit of inheritance of mammalian mtDNA
    • (2000) BioEssays , vol.22 , pp. 564-572
    • Jacobs, H.T.1
  • 8
    • 0023518420 scopus 로고
    • Amounts of mitochondrial DNA and abundance of some mitochondrial gene transcripts in early mouse embryos
    • (1987) Dev. Biol. , vol.123 , pp. 364-374
    • Piko, L.1    Taylor, K.D.2
  • 9
    • 0034693067 scopus 로고    scopus 로고
    • Differential regulation of the catalytic and accessory subunit genes of Drosophila mitochondrial DNA polymerase
    • (2000) J. Biol. Chem. , vol.275 , pp. 33123-33133
    • Lefai, E.1
  • 11
    • 0034598918 scopus 로고    scopus 로고
    • Coupled leading- and lagging-strand synthesis of mammalian mitochondrial DNA
    • (2000) Cell , vol.100 , pp. 515-524
    • Holt, I.J.1
  • 13
    • 0033538473 scopus 로고    scopus 로고
    • Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1
    • (1999) Cell , vol.98 , pp. 115-124
    • Wu, Z.1
  • 15
    • 0033958061 scopus 로고    scopus 로고
    • Biogenesis of giant mitochondria during insect flight muscle development in the locust, Locusta migratoria (L.). Transcription, translation and copy number of mitochondrial DNA
    • (2000) Eur. J. Biochem. , vol.267 , pp. 11-17
    • Sogl, B.1
  • 16
    • 0016327931 scopus 로고
    • The number of mitochondrial deoxyribonucleic acid genomes in mouse L and human HeLa cells. Quantitative isolation of mitochondrial deoxyribonucleic acid
    • (1974) J. Biol. Chem. , vol.249 , pp. 7991-7995
    • Bogenhagen, D.1    Clayton, D.A.2
  • 18
    • 0019978703 scopus 로고
    • Replication of animal mitochondrial DNA
    • (1982) Cell , vol.28 , pp. 693-705
    • Clayton, D.A.1
  • 19
    • 0034128803 scopus 로고    scopus 로고
    • Rearrangements of human mitochondrial DNA (mtDNA): New insights into the regulation of mtDNA copy number and gene expression
    • (2000) Mol. Biol. Cell , vol.11 , pp. 1471-1485
    • Tang, Y.1
  • 22
    • 0018750887 scopus 로고
    • Biochemical and electron microscopic evidence that cell nucleus negatively controls mitochondrial genomic activity in early sea urchin development
    • (1979) Proc. Natl. Acad. Sci. U.S.A. , vol.76 , pp. 1916-1920
    • Rinaldi, A.M.1
  • 23
    • 0033652821 scopus 로고    scopus 로고
    • Overexpression of the catalytic subunit of DNA polymerase gamma results in depletion of mitochondrial DNA in Drosophila melanogaster
    • (2000) Mol. Gen. Genet. , vol.264 , pp. 37-46
    • Lefai, E.1
  • 24
    • 0034637514 scopus 로고    scopus 로고
    • In vivo functional analysis of the human mitochondrial DNA polymerase POLG expressed in cultured human cells
    • (2000) J. Biol. Chem. , vol.275 , pp. 24818-24828
    • Spelbrink, J.N.1
  • 25
    • 0032728444 scopus 로고    scopus 로고
    • The tamas gene, identified as a mutation that disrupts larval behavior in Drosophila melanogaster, codes for the mitochondrial DNA polymerase catalytic subunit (DNApol-gamma125)
    • (1999) Genetics , vol.153 , pp. 1809-1824
    • Iyengar, B.1
  • 26
    • 0033591435 scopus 로고    scopus 로고
    • Functional interactions of mitochondrial DNA polymerase and single-stranded DNA-binding protein. Template-primer DNA binding and initiation and elongation of DNA strand synthesis
    • (1999) J. Biol. Chem. , vol.274 , pp. 14779-14785
    • Farr, C.L.1
  • 27
    • 0034608014 scopus 로고    scopus 로고
    • Regulation of mitochondrial single-stranded DNA-binding protein gene expression links nuclear and mitochondrial DNA replication in Drosophila
    • (2000) J. Biol. Chem. , vol.275 , pp. 13628-13636
    • Ruiz De Mena, I.1
  • 28
    • 0035172433 scopus 로고    scopus 로고
    • Mitochondrial single-stranded DNA-binding protein is required for mtDNA replication and development in Drosophila melanogaster
    • in press
    • Mol. Biol. Cell
    • Maier, D.1
  • 30
    • 0031930319 scopus 로고    scopus 로고
    • Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice
    • (1998) Nat. Genet. , vol.18 , pp. 231-236
    • Larsson, N.G.1
  • 32
    • 0028029271 scopus 로고
    • Deficiency of the human mitochondrial transcription factor h-mtTFA in infantile mitochondrial myopathy is associated with mtDNA depletion
    • (1994) Hum. Mol. Genet. , vol.3 , pp. 1763-1769
    • Poulton, J.1
  • 33
    • 0032924872 scopus 로고    scopus 로고
    • Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression
    • (1999) Nat. Genet. , vol.21 , pp. 133-137
    • Wang, J.1
  • 34
    • 0033762782 scopus 로고    scopus 로고
    • Impaired insulin secretion and beta-cell loss in tissue-specific knockout mice with mitochondrial diabetes
    • (2000) Nat. Genet. , vol.26 , pp. 336-340
    • Silva, J.P.1
  • 36
    • 0032488920 scopus 로고    scopus 로고
    • Differential expression of mitochondrial DNA replication factors in mammalian tissues
    • (1998) J. Biol. Chem. , vol.273 , pp. 3447-3451
    • Schultz, R.A.1
  • 37
    • 0029982347 scopus 로고    scopus 로고
    • Mitochondrial DNA polymerase gamma is expressed and translated in the absence of mitochondrial DNA maintenance and replication
    • (1996) Nucleic Acids Res. , vol.24 , pp. 2753-2759
    • Davis, A.F.1
  • 38
    • 0032834613 scopus 로고    scopus 로고
    • Mechanisms of human mitochondrial DNA maintenance: The determining role of primary sequence and length over function
    • (1999) Mol. Biol. Cell , vol.10 , pp. 3345-3356
    • Moraes, C.T.1
  • 39
    • 0035101674 scopus 로고    scopus 로고
    • Crystal structure and deletion analysis show that the accessory subunit of mammalian DNA polymerase, polB, functions as a homodimer
    • (2001) Mol. Cell , vol.7 , pp. 43-54
    • Carrodeguas, J.A.1
  • 40
    • 0033578357 scopus 로고    scopus 로고
    • The accessory subunit of mtDNA polymerase shares structural homology with aminoacyl-tRNA synthetases: Implications for a dual role as a primer recognition factor and processivity clamp
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 9527-9532
    • Fan, L.1
  • 41
    • 0033010856 scopus 로고    scopus 로고
    • The accessory subunit of Xenopus laevis mitochondrial DNA polymerase gamma increases processivity of the catalytic subunit of human DNA polymerase gamma and is related to class II aminoacyl-tRNA synthetases
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 4039-4046
    • Carrodeguas, J.A.1
  • 42
    • 0033928582 scopus 로고    scopus 로고
    • Maintenance of human rearranged mitochondrial DNAs in long-term cultured transmitochondrial cell lines
    • (2000) Mol. Biol. Cell , vol.11 , pp. 2349-2358
    • Tang, Y.1
  • 43
    • 0033613865 scopus 로고    scopus 로고
    • Thymidine phosphorylase gene mutations in MNGIE, a human mitochondrial disorder
    • (1999) Science , vol.283 , pp. 689-692
    • Nishino, I.1
  • 44
    • 0034604506 scopus 로고    scopus 로고
    • Role of adenine nucleotide translocator 1 in mtDNA maintenance
    • (2000) Science , vol.289 , pp. 782-785
    • Kaukonen, J.1
  • 45
    • 0024282748 scopus 로고
    • Mitochondrial DNA polymerase from Drosophila melanogaster embryos: Kinetics, processivity, and fidelity of DNA polymerization
    • (1988) Biochemistry , vol.27 , pp. 6046-6054
    • Wernette, C.M.1
  • 46
    • 0022577219 scopus 로고
    • The base substitution fidelity of eucaryotic DNA polymerases. Mispairing frequencies, site preferences, insertion preferences, and base substitution by dislocation
    • (1986) J. Biol. Chem. , vol.261 , pp. 160-166
    • Kunkel, T.A.1    Alexander, P.S.2
  • 48
    • 0030951244 scopus 로고    scopus 로고
    • Tissue-specific selection for different mtDNA genotypes in heteroplasmic mice
    • (1997) Nat. Genet. , vol.16 , pp. 93-95
    • Jenuth, J.P.1
  • 49
    • 0028262917 scopus 로고
    • Human mitochondria and mitochondrial genome function as a single dynamic cellular unit
    • (1994) J. Cell Biol. , vol.125 , pp. 43-50
    • Hayashi, J.1
  • 51
    • 0034646656 scopus 로고    scopus 로고
    • Very rare complementation between mitochondria carrying different mitochondrial DNA mutations points to intrinsic genetic autonomy of the organelles in cultured human cells
    • (2000) J. Biol. Chem. , vol.275 , pp. 11207-11215
    • Enriquez, J.A.1
  • 54
    • 0026015896 scopus 로고
    • mtDNA depletion with variable tissue expression: A novel genetic abnormality in mitochondrial diseases
    • (1991) Am. J. Hum. Genet. , vol.48 , pp. 492-501
    • Moraes, C.T.1
  • 55
    • 0029086201 scopus 로고
    • Early-onset encephalomyopathy associated with tissue-specific mitochondrial DNA depletion: A morphological, biochemical and molecular-genetic study
    • (1995) J. Neurol. , vol.242 , pp. 547-556
    • Mariotti, C.1
  • 56
    • 0031924550 scopus 로고    scopus 로고
    • Familial mitochondrial DNA depletion in liver: Haplotype analysis of candidate genes
    • (1998) Hum. Genet. , vol.102 , pp. 327-331
    • Spelbrink, J.N.1
  • 58
    • 0017758576 scopus 로고
    • Mouse L cell mitochondrial DNA molecules are selected randomly for replication throughout the cell cycle
    • (1977) Cell , vol.11 , pp. 719-727
    • Bogenhagen, D.1    Clayton, D.A.2
  • 60
    • 0025039698 scopus 로고
    • Mitochondrial DNA copy number is proportional to total cell DNA under a variety of growth conditions
    • (1990) J. Biol. Chem. , vol.265 , pp. 14802-14807
    • Shay, J.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.