A role for BMP signalling in heart looping morphogenesis in Xenopus

Developmental Biology

Volumn 232, Issue 1, 2001, Pages 191-203

  Breckenridge, Ross A ^a   Mohun, Tim J ^b   Amaya, Enrique ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

Bone morphogenetic protein; Heart; Left right axis; Transgenics; Xenopus

Indexed keywords

BONE MORPHOGENETIC PROTEIN;

ARTICLE; EMBRYO; EMBRYO DEVELOPMENT; GENE EXPRESSION REGULATION; HEART DEVELOPMENT; IN SITU HYBRIDIZATION; MORPHOGENESIS; NONHUMAN; PRIORITY JOURNAL; RANDOMIZATION; SIGNAL TRANSDUCTION; TRANSGENE; XENOPUS; ZEBRA FISH;

DANIO RERIO;

EID: 0035313303     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.2001.0164     Document Type: Article

References (57)

1. A method for generating transgenic frog embryos
2. Regulation of midline development by antagonism of lefty and nodal signalling
3. XBF-1, a winged helix transcription factor with dual activity, has a role in positioning neurogenesis in Xenopus competent ectoderm
4. Regulation of gut and heart left-right asymmetry by context-dependent interactions between Xenopus Lefty and BMP4 signaling
5. A gene trap approach in Xenopus
6. The homeobox gene Pitx2: Mediator of asymmetric left-right signalling in vertebrate heart and gut looping
7. Mechanism of left-right determination in vertebrates
8. A constitutive mutation of ALK5 disrupts cardiac looping and morphogenesis in mice
9. Left-right pattern of cardiac BMP4 may drive asymmetry of the heart in zebrafish
10. Bone morphogenetic protein 2 in the early development of Xenopus laevis
11. Relationship between asymmetric nodal expression and the direction of embryonic turning
12. Bone morphogenetic protein 4: A ventralising factor in early Xenopus development
13. Linkage of cardiac left-right asymmetry and dorsal-anterior development in Xenopus
14. Role of notochord in specification of cardiac left-right orientation in zebrafish and Xenopus
15. Bmp-4 acts as a morphogen in dorsoventral mesoderm patterning in Xenopus
16. On the function of BMP-4 in patterning the marginal zone of the Xenopus embryo
17. Parsing the heart: Genetic modules for organ assembly
18. In situ hybridisation: An improved whole-mount method for Xenopus embryos
19. Ventral mesodermal patterning in Xenopus embryos: Expression patterns and activities of BMP-2 and BMP-4
20. Bone morphogenetic proteins in development
21. Tbx5 is essential for heart development
22. The left-right coordinator: The role of Vg1 in organizing left-right axis formation
23. Transgenic Xenopus embryos from sperm nuclear transplantations reveal FGF signalling requirements during gastrulation
24. BMP-binding modules in chordin: A model for signalling regulation in the extracellular space
25. A molecular pathway determining left-right asymmetry in chick embryogenesis
26. Left/right patterning signals and the independent regulation of different aspects of situs in the chick embryo
27. Control of mouse cardiac morphogenesis by transcription factor MEF2C
28. Left-right asymmetry of a nodal-related gene is regulated by dorsoanterior midline structures during Xenopus development
29. Combined BMP-2 and FGF-4, but neither factor alone induces cardiogenesis in non-precardiac embryonic mesoderm
30. Conserved left-right asymmetry of nodal expression and alterations in murine situs inversus
31. A Xenopus nodal-related gene that acts in synergy with noggin to induce complete secondary axis and notochord formation
32. Myogenic and morphogenic defects in heart tubes of murine embryos lacking the homeobox gene Nkx2-5
33. Upstream sequences required for tissue-specific activation of the cardiac actin gene in Xenopus laevis embryos
34. The morphology of heart development in Xenopus laevis
35. A Xenopus gene, Xbr-1, defines a novel class of homeobox genes and is expressed in the dorsal ciliary margin of the eye
36. Cardiac looping and the vertebrate left-right axis: Antagonism of left-sided Vg1 activity by a right-sided ALK2-dependent pathway
37. Zebrafish nodal-related genes are implicated in axial patterning and establishing left-right asymmetry
38. Pitx2 determines left-right asymmetry of internal organs in vertebrates
39. Functional differences among Xenopus nodal-related genes in left-right axis determination
40. Regulation of left-right asymmetries in the zebrafish by Shh and BMP4
41. BMP2 is required for heart development during a distinct time period
42. A role for bone morphogenetic proteins in the induction of cardiac myogenesis
43. Retinoic acid directs cardiac laterality and the expression of early markers of precardiac asymmetry
44. BMP signaling is required for heart formation in vertebrates
45. Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos
46. Secreted noggin protein mimics the Spemann organizer in dorsalizing Xenopus mesoderm
47. Regulation of cardiac mesodermal and neural crest by development by the bHLH factor dHAND
48. Cloning and expression pattern of chicken Pitx2: A new component in the SHH signalling system controlling embryonic heart looping
49. Xenopus msx1 mediates epidermal induction and neural inhibition by BMP4
50. A novel Xenopus homologue of bone morphogenetic protein-7 (BMP-7)
51. Retinoic acid affects left-right patterning
52. Bone morphogenetic protein 4 is required for mesoderm formation and patterning in the mouse
53. Antagonistic signalling by Caronte, a novel Cerberus-related gene, establishes left-right asymmetric gene expression
54. An indelible lineage marker for Xenopus using a mutated green fluorescent protein
55. Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development
56. Programmed cell death in the developing heart: Regulation by BMP4 and FGF2
57. The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4