Xenopus msx1 mediates epidermal induction and neural inhibition by BMP4

Development

Volumn 124, Issue 16, 1997, Pages 3037-3044

  Suzuki, Atsushi ^a,b   Ueno, Naoto ^b   Hemmati Brivanlou, Ali ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b HOKKAIDO UNIVERSITY   (Japan)

Author keywords

BMP4; Epidermis; Induction; msx1; Xenopus

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 4; CELL RECEPTOR; GROWTH FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EARLY RESPONSE GENE; ECTODERM; EMBRYO; EMBRYO DEVELOPMENT; EPIDERMIS; EXPLANT; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE OVEREXPRESSION; HOMEOBOX; NERVE CELL DIFFERENTIATION; NERVE CELL INHIBITION; NERVOUS TISSUE; NONHUMAN; PRIORITY JOURNAL; XENOPUS;

ANIMALS; BODY PATTERNING; BONE MORPHOGENETIC PROTEIN RECEPTORS; BONE MORPHOGENETIC PROTEINS; CYCLOHEXIMIDE; ECTODERM; EMBRYONIC INDUCTION; EPIDERMIS; GASTRULA; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, HOMEOBOX; HOMEODOMAIN PROTEINS; MSX1 TRANSCRIPTION FACTOR; NERVOUS SYSTEM; PROTEIN SYNTHESIS INHIBITORS; RECEPTORS, CELL SURFACE; RECEPTORS, GROWTH FACTOR; RNA, MESSENGER; TRANSCRIPTION FACTORS; XENOPUS; XENOPUS PROTEINS;

ANIMALIA;

EID: 0030964620     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (70)

1. Altmann, C. R., Chow, R. L., Lang, R. A., and Hemmati-Brivanlou, A. (1997). Lens induction by Pax-6 in Xenopus laevis. Dev. Biol. 185, 119-123.
2. Baker, J. C., and Harland, R. M. (1996). A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway. Genes Dev. 10, 1880-1889.
3. Barlow, A. J., and Francis-West, P. H. (1997). Ectopic application of recombinant BMP-2 and BMP-4 can change patterning of developing chick facial primordia. Development 124, 391-398.
4. Bassez, T., Paris, J., Omilli, F., Dorel, C., and Osborne, H. B. (1990) Posttranscriptional regulation of ornithine decarboxylase in Xenopus laevis oocytes. Development 110, 955-962.
5. Catron, K. M., Wang, H., Hu, G., Shen, M. M., an Abate-Shen, C. (1996). Comparison of MSX-1 and MSX-2 suggests a molecular basis for functional redundancy. Mech. Dev. 55, 185-199.
6. Chen, X., Rubock, M. J., and Whitman, M. (1996). A transcriptional partner for MAD proteins in TGF-β Signalling. Nature 383, 691-696.
7. Chen, Y., and Solursh, M. (1995). Mirror-image duplication of the primary axis and heart in Xenopus embryos by the overexpression of Msx-1 gene. J. Exp. Zool 273, 170-174.
8. Cho, K. W. Y., Blumberg, B., Steinbeisser, H., and De Robertis, E. M. (1991). Molecular nature of Spemann's organizer: the role of the Xenopus homeobox gene goosecoid. Cell 67, 1111-1120.
9. Chomczynski, P., and Sacchi, N. (1987). Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159.
10. Christian, J. L., McMahon, J. A., McMahon, A. P., and Moon, R. T. (1991). Xwnt-8, a Xenopus Wnt-1/int-1-related gene responsive to mesoderm-inducing growth factors, may play a role in ventral mesodermal patterning during embryogenesis. Development 111, 1045-1055.
11. Clement, J. H., Fettes, P., Knöchel, S., Lef, J., and Knöchel, W. (1995). Bone morphogenetic protein 2 in the early development of Xenopus laevis. Mech. Dev. 52, 357-370.
12. Dale, L., Howes, G., Price, B. M. J., and Smith, J. C. (1992). Bone morphogenetic protein 4: a ventralizing factor in Xenopus development. Development 115, 573-585.
13. Davidson, D. (1995). The function and evolution of Msx genes: pointers and paradoxes. Trends Genet. 11, 405-411.
14. Eppert, K., Scherer, S. W., Ozcelik, H., Pirone, R., Hoodless, P., Kim, H., Tsui, L.-C., Bapat, B., Gallinger, S., Andrulis, I. L. et al. (1996). MADR2 maps to 18q21 and encodes a TGFβ-regulated MAD-related protein that is functionally mutated in colorectal carcinoma. Cell 86, 543-552.
15. Fainsod, A., Steinbeisser, H., and De Robertis, E. M. (1994). On the function of BMP-4 in patterning the marginal zone of the Xenopus embryo. EMBO J. 13, 5015-5025.
16. Godsave, S. F., and Slack, J. M. W. (1991). Single cell analysis of mesoderm formation in the Xenopus embryo. Development 111, 523-530.
17. Graff, J. M., Bansal, A., and Melton, D. A. (1996). Xenopus Mad proteins transduce distinct subsets of signals for the TGFβ superfamily. Cell 85, 479-487.
18. Graham, A., Francis-West, P., Brickell, P., and Lumsden, A. (1994). The signalling molecule BMP4 mediates apoptosis in the rhombencephalic neural crest. Nature 372, 684-686.
19. Grunz, H., and Tacke, L. (1989). Neural differentiation of Xenopus laevis ectoderm takes place after disaggregation and delayed reaggregation without inducer. Cell Diff. Devl. 28, 211-218.
20. Harland, R. M. (1991). In situ hybridization: an improved whole-mount method for Xenopus embryos. In Methods in Cell Biology (ed. B. K. Kay and H. B. Peng), pp. 685-695., San Diego: Academic Press Inc.
21. Hemmati-Brivanlou, A., de la Torre, J. R., Holt, C., Harland, R. M. (1991). Cephalic expression and molecular characterization of Xenopus En-2. Development 111, 715-724.
22. Hemmati-Brivanlou, A., and Melton, D. A. (1994). Inhibition of activin receptor signaling promotes neuralization in Xenopus. Cell 77, 273-281.
23. Hemmati-Brivanlou, A., and Thomsen, G. H. (1995). Ventral mesodermal patterning in Xenopus embryos: expression patterns and activities of BMP-2 and BMP-4. Dev. Genet. 17, 78-89.
24. Hemmati-Brivanlou, A., and Melton, D. A. (1997). Vertebrate embryonic cells will become nerve cells unless told otherwise. Cell 88, 13-17.
25. Hoodless, P. A., Haerry, T., Abdollah, S., Stapleton, M., O'Connor, M. B., Attisano, L., and Wrana, J. L. (1996). MADR1, a MAD-related protein that functions in BMP2 signaling pathways. Cell 85, 489-500.
26. Jabs, E. W., Müller, U., Li, X., Ma, L., Luo, W., Haworth, I. S., Klisak, I., Sparkes, R., Warman, M. L., Mulliken, J. B. et al. (1993). A mutation in the homeodomain of the human MSX2 gene in a family affected with autosomal dominant craniosynostosis. Cell 75, 443-450.
27. Jones, C. M., Lyons, K. M., Lapan, P. M., Wright, C. V. E., Hogan, B. J. M. (1992). DVR-4 (Bone Morphogenetic Protein-4) as a postero-ventralizing factor in Xenopus mesoderm induction. Development 115, 639-647.
28. Jones, C. M., Kuehn, M. R., Hogan, B. L. M., Smith, J. C., and Wright, C. V. E. (1995). Nodal-related signals induce axial mesoderm and dorsalize mesoderm during gastrulation. Development 121, 3651-3662.
29. Keller, R. (1991). Early embryonic development of Xenopus laevis. In Methods in Cell Biology (ed. B. K. Kay and H. B. Peng). pp. 61-113. San Diego: Academic Press Inc..
30. Kessler, D. S., and Melton, D. A. (1994). Vertebrate embryonic induction: mesodermal and neural patterning. Science 266, 596-604.
31. Kretzschmar, M., Liu, F., Hata, A., Doody, J., and Massagué, J. (1997). The TGF-β family mediator Smad1 is phospholylated directly and activated functionally by the BMP receptor kinase. Genes Dev. 11, 984-995.
32. Lagna, G., Hata, A., Hemmati-Brivanlou, A., and Massagué, J. (1996). Partnership between DPC4 and SMAD proteins in TGF-β signalling pathways. Nature 383, 832-836.
33. Liem, K. F., Jr., Tremml, G., Roelink, H., and Jessell, T. M. (1995). Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm. Cell 82, 969-979.
34. Liu, F., Hata, A., Baker, J. C., Doody, J., Carcamo, J., Harland, R. M., and Massagué, J. (1996). A human Mad protein acting as a BMP-regulated transcriptional activator. Nature 381, 620-623.
35. Massagué, J. (1996). TGFβ signaling: receptors, transducers, and mad proteins. Cell 85, 947-950.
36. Moos, M., Jr., Wang, S., and Krinks, M. (1995). Anti-dorsalizing morphogenetic protein is a novel TGF-β homolog expressed in the Spemann organizer. Development 121, 4293-4301.
37. Nieuwkoop, P. D., and Faber, J. (1967). Normal Table of Xenopus laevis (Daudin). Amsterdam: North Holland Publishing Company.
38. Piccolo, S., Sasai, Y., Lu, B., and De Robertis, E. M. (1996). Dorsoventral patterning in Xenopus: inhibition of ventral signals by direct binding of chordin to Bmp-4. Cell 86, 589-598.
39. Richter, K., Good, P. J., and Dawid, I. B. (1990). A developmentally regulated, nervous system-specific gene in Xenopus encodes a putative RNA-binding protein. New Biol. 2, 556-565.
40. Rosa, F. M. (1989). Mix.1, a homeobox mRNA inducible by mesoderm inducers, is expressed mostly in the presumptive endodermal cells of Xenopus embryos. Cell 57, 965-974.
41. Sargent, T. D., Jamrich, M., and Dawid, I. B. (1986). Cell interactions and the control of gene activity during early development of Xenopus laevis. Dev. Biol. 114, 238-246.
42. Sasai, Y., Lu, B., Steinbeisser, H., Geissert, D., Gont, L. K., and De Robertis, E. M. (1994). Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes. Cell 79, 779-790.
43. Sasai, Y., Lu, B., Steinbeisser, H., and De Robertis, E. M. (1995). Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus. Nature 376, 333-336.
44. Satokata, I., and Maas, R. (1994). Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development. Nature Genet. 6, 348-356.
45. Schmidt, J. F., Suzuki, A., Ueno, N., and Kimelman, D. (1995). Localized BMP-4 mediates dorsal/ventral patterning in the early Xenopus embryo. Dev. Biol. 169, 37-50.
46. Shimeld, S. M., McKay, I. J., and Sharpe, P. T. (1996). The murine homeobox gene Msx-3 shows highly restricted expression in the developing neural tube. Mech. Dev. 55, 201-210.
47. Slack, J. M. W. (1994). Inducing factors in Xenopus early embryos. Curr. Biol. 4, 116-126.
48. Smith, J. C., Price, B. M. J., Green, J. B. A., Weigel, D., and Herrmann, B. G. (1991). Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction. Cell 67, 79-87.
49. Smith, W. C., and Harland, R. M. (1991). Injected Xwnt-8 RNA acts early in Xenopus embryos to promote formation of a vegetal dorsalizing center. Cell 67, 753-765.
50. Sokol, S., Wong, G. G., and Melton, D. A. (1990). A mouse macrophage factor induces head structures and organizes a body axis in Xenopus. Science 249, 561-564.
51. Song, K., Wang, Y., and Sassoon, D. (1992). Expression of Hox-7.1 in myoblasts inhibits terminal differentiation and induces cell transformation. Nature 360, 477-481.
52. Su, M. W., Suzuki, H. R., Solursh, M., and Ramirez, F. (1991). Progressively restricted expression of a new homeobox-containing gene during Xenopus laevis embryogenesis. Development 111, 1179-1187.
53. Suzuki, A., Nishimatsu, S., Murakami, K., and Ueno, N. (1993). Differential expression of Xenopus BMPs in early embryos and tissues. Zool. Sci. 10, 175-178.
54. Suzuki, A., Shioda, N., and Ueno, N. (1995). Bone morphogenetic protein acts as a ventral mesoderm modifier in early Xenopus embryos. Develop. Growth & Differ. 37, 581-588.
55. Suzuki, A., Chang, C., Yingling, J. M., Wang, X.-F., and Hemmati-Brivanlou, A. (1997a). Smad5 induces ventral fates in Xenopus embryo. Dev. Biol. 184, 402-405.
56. Suzuki, A., Kaneko, E., Maeda, J., and Ueno, N. (1997b). Mesoderm induction by BMP-4 and -7 heterodimer. Biochem. Biophys. Res. Commun. 232, 153-156.
57. Suzuki, A., Kaneko, E., Ueno, N., and Hemmati-Brivanlou, A. (1997c). Regulation of epidermal inducion by BMP2 and BMP7 signaling. Dev. Biol., in press.
58. Thomsen, G., Woolf, T., Whitman, M., Sokol, S., Vaughan, J., Vale, W., and Melton, D. A. (1990). Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures. Cell 63, 485-493.
59. Thomsen, G. H., and Melton, D. A. (1993). Processed Vg1 protein is an axial mesoderm inducer in Xenopus. Cell 74, 433-441.
60. Thomsen, G. H. (1996). Xenopus mothers against decapentaplegic is an embryonic ventralizing agent that acts downstream of the BMP-2/4 receptor. Development 122, 2359-2366.
61. Vainio, S., Karavanova, I., Jowett, A., and Thesleff, I. (1993). Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development. Cell 75, 45-58.
62. Wang, Y., and Sassoon, D. (1995). Ectoderm-mesenchyme and mesenchyme-mesenchyme interactions regulate Msx-1 expression and cellular differentiation in the murine limb bud. Dev. Biol. 168, 374-382.
63. Watanabe, Y., and Le Douarin, N. M. (1996). A role for BMP-4 in the development of subcutaneous cartilage. Mech. Dev. 57, 69-78.
64. Weinstein, D. C., and Hemmati-Brivanlou, A. (1997). Neural induction in Xenopus laevis; evidence for the default model. Curr. Opin. Neurobiol. 7, 7-12.
65. Wilson, P. A., and Hemmati-Brivanlou, A. (1995). Induction of epidermis and inhibition of neural fate by Bmp-4. Nature 376, 331-333.
66. Woloshin, P., Song, K., Degnin, C., Killary, A. M., Goldhamer, D. J., Sassoon, D., and Thayer, M. J. (1995). MSX1 inhibits myoD expression in fibroblast × 10T1/2 cell hybrids. Cell 82, 611-620.
67. Wrana, J. L., Attisano, L., Wieser, R., Ventura, F., and Massagué, J. (1994). Mechanism of activation of the TGF-β receptor. Nature 370, 341-347.
68. Xu, R.-H., Kim, J., Taira, M., Zhan, S., Sredni, D., and Rung, H.-F. (1995). A dominant negative bone morphogenetic protein 4 receptor causes neuralization in Xenopus ectoderm. Biochem. Biophys. Res. Commun. 212, 212-219.
69. Yamashita, H., ten Dijke, P., Heldin, C.-H., and Miyazono, K. (1996) Bone morphogenetic protein receptors. Bone 19, 569-574.
70. Zimmerman, L. B., De Jesús-Escobar, J. M., and Harland, R. M. (1996). The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4. Cell 86, 599-606.