Use of protein-interaction maps to formulate biological questions

Current Opinion in Chemical Biology

Volumn 5, Issue 1, 2001, Pages 57-62

  Boulton, Simon J ^a,b   Vincent, Sylvie ^a   Vidal, Marc ^c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

DATA BASE; GENE MAPPING; GENE SEQUENCE; NONHUMAN; PROTEIN PROTEIN INTERACTION; REVIEW; YEAST;

EID: 0035253194     PISSN: 13675931     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1367-5931(00)00168-X     Document Type: Review

References (37)

1. Yeast two-hybrid systems and protein interaction mapping projects for yeast and worms
2. Toward a protein-protein interaction map of the budding yeast: A comprehensive system to examine two-hybrid interactions in all possible combinations between yeast proteins
3. Genome-wide protein interaction screens reveal functional networks involving Sm-like proteins
4. A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae
5. Protein interaction mapping in C. elegans using proteins involved in vulval development
6. Filamentous fusion phage: Novel expression vectors that display cloned antigens on the virion surface
7. An in vivo library-versus-library selection of optimized protein-protein interactions
8. A protein linkage map of Escherichia coli bacteriophage T7
9. From molecular to modular cell biology
10. Genetics of RAS signaling in C. elegans
11. LAG-3 is a putative transcriptional activator in the C. elegans Notch pathway
12. RNAi - Prospects for a general technique for determining gene function
13. Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis
14. Large-scale analysis of the yeast genome by transposon tagging and gene disruption
15. Gene targeting by homologous recombination in Drosophila
16. Functional discovery via a compendium of expression profiles
17. A biochemical genomics approach for identifying genes by the activity of their products
18. Gateway cloning: Application to the cloning of large numbers of open reading frames or ORFeomes
19. The FHA domain is a modular phosphopeptide recognition motif
20. Fluorescence energy transfer as a spectroscopic ruler
21. Fluorescence resonance energy transfer
22. Mapping interactions between nuclear transport factors in living cells reveals pathways through the nuclear pore complex
23. Interaction blues: Protein interactions monitored in live mammalian cells by beta-galactosidase complementation
24. NURD-complex genes antagonise Ras-induced vulval development in Caenorhabditis elegans
25. Reverse two-hybrid and one-hybrid systems to detect dissociation of protein-protein and DNA-protein interactions
26. Mutational analysis of STE5 in the yeast Saccharomyces cerevisiae: Application of a differential interaction trap assay for examining protein-protein interactions
27. Two classes of human papillomavirus type 16 E1 mutants suggest pleiotropic conformational constraints affecting E1 multimerization, E2 interaction, and interaction with cellular proteins
28. A green fluorescent protein-based reverse two-hybrid system: Application to the characterization of large numbers of potential protein-protein interactions
29. A positive genetic selection for disrupting protein-protein interactions: Identification of CREB mutations that prevent association with the coactivator CBP
30. Prospects for drug screening using the reverse two-hybrid system
31. Transdominant genetic analysis of a growth control pathway
32. Genetic selection of peptide inhibitors of biological pathways
33. Mutagenesis' by peptide aptamers identifies genetic network members and pathway connections
34. Genetic selection for dissociative inhibitors of designated protein-protein interactions
35. Yeast two-hybrid: So many interactions, (in) so little time...
36. Functional genomic analysis of C. elegans chromosome I by systematic RNA interference
37. Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III