Cytochrome P450-generated reactive metabolites cause mitochondrial permeability transition, caspase activation, and apoptosis in rat hepatocytes

Hepatology

Volumn 32, Issue 2, 2000, Pages 303-311

  Haouzi, Delphine ^a   Lekéhal, Mounia ^a   Moreau, Alain ^b   Moulis, Claude ^c   Feldmann, Gérard ^b   Robin, Marie Anne ^a   Lettéron, Philippe ^a   Fau, Daniel ^a   Pessayre, Dominique ^a  

^a BEAUJON HOSPITAL   (France)

^b INSERM   (France)

^c UNIVERSITÉ DE TOULOUSE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CALMIDAZOLIUM; CASPASE; CYCLOSPORIN A; CYTOCHROME C PEROXIDASE; CYTOCHROME P450; DITERPENOID; TROLEANDOMYCIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; LIVER CELL; LIVER MITOCHONDRION; LIVER TOXICITY; MEMBRANE PERMEABILITY; MEMBRANE RUPTURE; METABOLITE; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0033865278     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.2000.9034     Document Type: Article

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