-
1
-
-
0032191115
-
Chronic obstructive pulmonary disease: New opportunities for drug development
-
Barnes PJ 1998a Chronic obstructive pulmonary disease: new opportunities for drug development. Trends Pharmacol Sci 19:415-423
-
(1998)
Trends Pharmacol Sci
, vol.19
, pp. 415-423
-
-
Barnes, P.J.1
-
2
-
-
0031898818
-
New therapies for chronic obstructive pulmonary disease
-
Barnes PJ 1998b New therapies for chronic obstructive pulmonary disease. Thorax 53:137-147
-
(1998)
Thorax
, vol.53
, pp. 137-147
-
-
Barnes, P.J.1
-
3
-
-
0033093103
-
Genetics and pulmonary medicine. 9. Molecular genetics of chronic obstructive pulmonary disease
-
Barnes PJ 1999 Genetics and pulmonary medicine. 9. Molecular genetics of chronic obstructive pulmonary disease. Thorax 54:245-252
-
(1999)
Thorax
, vol.54
, pp. 245-252
-
-
Barnes, P.J.1
-
4
-
-
0030615201
-
Nuclear factor-κB: A pivotal transcription factor in chronic inflammatory diseases
-
Barnes PJ, Karin M 1997 Nuclear factor-κB: a pivotal transcription factor in chronic inflammatory diseases. New Engl J Med 336:1066-1071
-
(1997)
New Engl J Med
, vol.336
, pp. 1066-1071
-
-
Barnes, P.J.1
Karin, M.2
-
7
-
-
0035219118
-
Matrix metalloproteinases and inhibitors
-
Chronic obstructive pulmonary disease: pathogenesis to treatment. Wiley, Chichester
-
Cawston T 2001 Matrix metalloproteinases and inhibitors. In: Chronic obstructive pulmonary disease: pathogenesis to treatment. Wiley, Chichester (Novartis Found Symp 234) p 205-228
-
(2001)
Novartis Found Symp
, vol.234
, pp. 205-228
-
-
Cawston, T.1
-
8
-
-
0032696013
-
Effect of high dose inhaled steroid on cells, cytokines and proteases in induced sputum in chronic obstructive pulmonary disease
-
Culpitt SV, Nightingale JA, Barnes PJ 1999 Effect of high dose inhaled steroid on cells, cytokines and proteases in induced sputum in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 160:1635-1639
-
(1999)
Am J Respir Crit Care Med
, vol.160
, pp. 1635-1639
-
-
Culpitt, S.V.1
Nightingale, J.A.2
Barnes, P.J.3
-
9
-
-
0028265386
-
Upregulation of adhesion molecules in the bronchial mucosa of subjects with chronic obstructive bronchitis
-
Di Stefano A, Maestrelli P, Roggeri A et al 1994 Upregulation of adhesion molecules in the bronchial mucosa of subjects with chronic obstructive bronchitis. Am J Respir Crit Care Med 149:803-810
-
(1994)
Am J Respir Crit Care Med
, vol.149
, pp. 803-810
-
-
Di Stefano, A.1
Maestrelli, P.2
Roggeri, A.3
-
10
-
-
0033534194
-
Tiotropium (Spiriva): Mechanistical considerations and clinical profile in obstructive lung disease
-
Disse B, Speck GA, Rominger KL, Witek TJ JR, Hammer R 1999 Tiotropium (Spiriva): mechanistical considerations and clinical profile in obstructive lung disease. Life Sci 64:457-464
-
(1999)
Life Sci
, vol.64
, pp. 457-464
-
-
Disse, B.1
Speck, G.A.2
Rominger, K.L.3
Witek T.J., Jr.4
Hammer, R.5
-
13
-
-
0032880124
-
The interrelationship of sputum inflammatory markers in patients with chronic bronchitis
-
Hill AT, Bayley D, Stockley RA 1999 The interrelationship of sputum inflammatory markers in patients with chronic bronchitis. Am J Respir Crit Care Med 160:893-898
-
(1999)
Am J Respir Crit Care Med
, vol.160
, pp. 893-898
-
-
Hill, A.T.1
Bayley, D.2
Stockley, R.A.3
-
14
-
-
0030071687
-
Differences in interleukin-8 and tumor necrosis factor-α in induced sputum from patients with chronic obstructive pulmonary disease or asthma
-
Keatings VM, Collins PD, Scott DM, Barnes PJ 1996 Differences in interleukin-8 and tumor necrosis factor-α in induced sputum from patients with chronic obstructive pulmonary disease or asthma. Am J Respir Crit Care Med 153:530-534
-
(1996)
Am J Respir Crit Care Med
, vol.153
, pp. 530-534
-
-
Keatings, V.M.1
Collins, P.D.2
Scott, D.M.3
Barnes, P.J.4
-
16
-
-
14444268539
-
Novel synthetic inhibitors of selectin-mediated cell adhesion: Synthesis of 1,6-bis[3-(3-carboxymethylphenyl)-4-(2-α-D-mannopyranosyloxy)-phenyl] hexane (TBC1269)
-
Kogan TP, Dupré B, Bui H et al 1998 Novel synthetic inhibitors of selectin-mediated cell adhesion: synthesis of 1,6-bis[3-(3-carboxymethylphenyl)-4-(2-α-D-mannopyranosyloxy)-phenyl] hexane (TBC1269). J Med Chem 41:1099-1111
-
(1998)
J Med Chem
, vol.41
, pp. 1099-1111
-
-
Kogan, T.P.1
Dupré, B.2
Bui, H.3
-
17
-
-
0028855894
-
IL-10 inhibits metalloproteinase and stimulates TIMP-1 production in human mononuclear phagocytes
-
Lacraz S, Nicod LP, Chicheportiche R, Welgus HG, Dayer JM 1995 IL-10 inhibits metalloproteinase and stimulates TIMP-1 production in human mononuclear phagocytes. J Clin Invest 96:2304-2310
-
(1995)
J Clin Invest
, vol.96
, pp. 2304-2310
-
-
Lacraz, S.1
Nicod, L.P.2
Chicheportiche, R.3
Welgus, H.G.4
Dayer, J.M.5
-
18
-
-
0033030207
-
p38 mitogen-activated protein kinase inhibitors - Mechanisms and therapeutic potentials
-
Lee JC, Kassis S, Kumar S, Badger A, Adams JL 1999 p38 mitogen-activated protein kinase inhibitors - mechanisms and therapeutic potentials. Pharmacol Ther 82:389-397
-
(1999)
Pharmacol Ther
, vol.82
, pp. 389-397
-
-
Lee, J.C.1
Kassis, S.2
Kumar, S.3
Badger, A.4
Adams, J.L.5
-
19
-
-
0032509889
-
Chemokines - Chemotactic cytokines that mediate inflammation
-
Luster AD 1998 Chemokines - chemotactic cytokines that mediate inflammation. New Engl J Med 338:436-445
-
(1998)
New Engl J Med
, vol.338
, pp. 436-445
-
-
Luster, A.D.1
-
20
-
-
0035218679
-
Oxidants/antioxidants and chronic obstructive pulmonary disease: Pathogenesis to therapy
-
Chronic obstructive pulmonary disease: pathogenesis to treatment. Wiley, Chichester
-
MacNee W 2001 Oxidants/antioxidants and chronic obstructive pulmonary disease: pathogenesis to therapy. In: Chronic obstructive pulmonary disease: pathogenesis to treatment. Wiley, Chichester (Novartis Found Symp 234) p 169-188
-
(2001)
Novartis Found Symp
, vol.234
, pp. 169-188
-
-
MacNee, W.1
-
21
-
-
0035218632
-
Alveolus formation: Critical period, plasticity and retinoid regulation
-
Chronic obstructive pulmonary disease: pathogenesis to treatment. Wiley, Chichester
-
Massaro D 2001 Alveolus formation: critical period, plasticity and retinoid regulation. In: Chronic obstructive pulmonary disease: pathogenesis to treatment. Wiley, Chichester (Novartis Found Symp 234) p 229-243
-
(2001)
Novartis Found Symp
, vol.234
, pp. 229-243
-
-
Massaro, D.1
-
22
-
-
0033538340
-
Differential IKK activation and IκBa degradation by interleukin-1β and tumor necrosis factor-α in human U937 monocytic cells: Evidence for additional regulatory steps in κB-dependent transcription
-
Nasuhara Y, Adcock IM, Catley M, Barnes PJ, Newton R 1999 Differential IKK activation and IκBa degradation by interleukin-1β and tumor necrosis factor-α in human U937 monocytic cells: evidence for additional regulatory steps in κB-dependent transcription. J Biol Chem 274:19965-19972
-
(1999)
J Biol Chem
, vol.274
, pp. 19965-19972
-
-
Nasuhara, Y.1
Adcock, I.M.2
Catley, M.3
Barnes, P.J.4
Newton, R.5
-
23
-
-
0025225659
-
Effect of selective phosphodiesterase inhibitors on the polymorphonuclear leukocyte respiratory burst
-
Nielson CP, Vestal RE, Sturm RJ, Heaslip R 1990 Effect of selective phosphodiesterase inhibitors on the polymorphonuclear leukocyte respiratory burst. J Allergy Clin Immunol 86:801-808
-
(1990)
J Allergy Clin Immunol
, vol.86
, pp. 801-808
-
-
Nielson, C.P.1
Vestal, R.E.2
Sturm, R.J.3
Heaslip, R.4
-
24
-
-
0031922793
-
Hepatocyte growth factor (HGF) acts as a mesenchyme-derived morphogenic factor during fetal lung development
-
Ohmichi H, Koshimizu U, Matsumoto K, Nakamura T 1998 Hepatocyte growth factor (HGF) acts as a mesenchyme-derived morphogenic factor during fetal lung development. Development 125:1315-1324
-
(1998)
Development
, vol.125
, pp. 1315-1324
-
-
Ohmichi, H.1
Koshimizu, U.2
Matsumoto, K.3
Nakamura, T.4
-
25
-
-
0345188819
-
Long-term treatment with inhaled budesonide in persons with mild chronic obstructive pulmonary disease who continue smoking
-
Pauwels RA, Lofdahl CG, Laitinen LA et al 1999 Long-term treatment with inhaled budesonide in persons with mild chronic obstructive pulmonary disease who continue smoking. N Engl J Med 340:1548-1553
-
(1999)
N Engl J Med
, vol.340
, pp. 1548-1553
-
-
Pauwels, R.A.1
Lofdahl, C.G.2
Laitinen, L.A.3
-
26
-
-
0031896459
-
Neuroregulation of mucus secretion by opioid receptors and K(ATP) and BK(Ca) channels in ferret trachea in vitro
-
Ramnarine SI, Liu YC, Rogers DF 1998 Neuroregulation of mucus secretion by opioid receptors and K(ATP) and BK(Ca) channels in ferret trachea in vitro. Br J Pharmacol 123:1631-1638
-
(1998)
Br J Pharmacol
, vol.123
, pp. 1631-1638
-
-
Ramnarine, S.I.1
Liu, Y.C.2
Rogers, D.F.3
-
27
-
-
0035219153
-
Genetics of chronic obstructive pulmonary disease
-
Chronic obstructive pulmonary disease: pathogenesis to treatment. Wiley, Chichester
-
Silverman E 2001 Genetics of chronic obstructive pulmonary disease. In: Chronic obstructive pulmonary disease: pathogenesis to treatment. Wiley, Chichester (Novartis Found Symp 234) p 45-65
-
(2001)
Novartis Found Symp
, vol.234
, pp. 45-65
-
-
Silverman, E.1
-
28
-
-
0035218742
-
Proteases and antiproteases
-
Chronic obstructive pulmonary disease: pathogenesis to treatment. Wiley, Chichester
-
Stockley RA 2001 Proteases and antiproteases. In: Chronic obstructive pulmonary disease: pathogenesis to treatment. Wiley, Chichester (Novartis Found Symp 234) p 189-204
-
(2001)
Novartis Found Symp
, vol.234
, pp. 189-204
-
-
Stockley, R.A.1
-
29
-
-
0033106501
-
Ariflo (SB 207499), a second generation phosphodiesterase 4 inhibitor for the treatment of asthma and COPD: From concept to clinic
-
Torphy TJ, Barnette MS, Underwood DC et al 1999 Ariflo (SB 207499), a second generation phosphodiesterase 4 inhibitor for the treatment of asthma and COPD: from concept to clinic. Pulm Pharmacol Ther 12:131-136
-
(1999)
Pulm Pharmacol Ther
, vol.12
, pp. 131-136
-
-
Torphy, T.J.1
Barnette, M.S.2
Underwood, D.C.3
-
30
-
-
0030835754
-
Multiple doses of intravenous interleukin 10 in steroid-refractory Crohn's disease. Crohn's Disease Study Group
-
van Deventer SJ, Elson CO, Fedorak RN 1997 Multiple doses of intravenous interleukin 10 in steroid-refractory Crohn's disease. Crohn's Disease Study Group. Gastroenterology 113:383-389
-
(1997)
Gastroenterology
, vol.113
, pp. 383-389
-
-
Van Deventer, S.J.1
Elson, C.O.2
Fedorak, R.N.3
-
31
-
-
0029947193
-
Association of chronic mucus hypersecretion with FEV1 decline and chronic obstructive pulmonary disease morbidity. Copenhagen City Heart Study Group
-
Vestbo J, Prescott E, Lange P 1996 Association of chronic mucus hypersecretion with FEV1 decline and chronic obstructive pulmonary disease morbidity. Copenhagen City Heart Study Group. Am J Respir Crit Care Med 153:1530-1535
-
(1996)
Am J Respir Crit Care Med
, vol.153
, pp. 1530-1535
-
-
Vestbo, J.1
Prescott, E.2
Lange, P.3
-
32
-
-
0033033913
-
Phosphodiesterase 4B2 is the predominant phosphodiesterase species and undergoes differential regulation of gene expression in human monocytes and neutrophils
-
Wang P, Wu P, Ohleth KM, Egan RW, Billah MM 1999 Phosphodiesterase 4B2 is the predominant phosphodiesterase species and undergoes differential regulation of gene expression in human monocytes and neutrophils. Mol Pharmacol 56:170-174
-
(1999)
Mol Pharmacol
, vol.56
, pp. 170-174
-
-
Wang, P.1
Wu, P.2
Ohleth, K.M.3
Egan, R.W.4
Billah, M.M.5
-
33
-
-
0032562614
-
Identification of a potent, selective non-peptide CXCR2 antagonist that inhibits interleukin-8-induced neutrophil migration
-
White JR, Lee JM, Young PR et al 1998 Identification of a potent, selective non-peptide CXCR2 antagonist that inhibits interleukin-8-induced neutrophil migration. J Biol Chem 273:10095-10098
-
(1998)
J Biol Chem
, vol.273
, pp. 10095-10098
-
-
White, J.R.1
Lee, J.M.2
Young, P.R.3
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