Response of anticoagulant pathways in disseminated intravascular coagulation

Seminars in Thrombosis and Hemostasis

Volumn 27, Issue 6, 2001, Pages 619-631

  Taylor F B , Jr ^a  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

Author keywords

E. coli sepsis; Endothelium; Endotoxemia; Nonovert DIC; Protein C network

Indexed keywords

ANTITHROMBIN; BIOLOGICAL MARKER; BLOOD CLOTTING FACTOR 10A; ENDOTOXIN; FIBRIN DEGRADATION PRODUCT; FIBRIN MONOMER; FIBRINOGEN; PLASMINOGEN ACTIVATOR INHIBITOR 3; PROTEIN C; THROMBIN ANTITHROMBIN COMPLEX; TISSUE FACTOR PATHWAY INHIBITOR;

ANTICOAGULATION; ARTICLE; BLOOD CLOTTING; DISSEMINATED INTRAVASCULAR CLOTTING; ENDOTOXEMIA; ESCHERICHIA COLI; FIBRINOLYSIS; GRAM NEGATIVE SEPSIS; HEMOSTASIS; HUMAN; INFLAMMATION; MICROVASCULATURE; NONHUMAN; PHOSPHOLIPID VESICLE; PRIORITY JOURNAL; STRESS; VASCULAR ENDOTHELIUM;

ANIMALS; BLOOD COAGULATION; ENDOTHELIUM, VASCULAR; ESCHERICHIA COLI INFECTIONS; HUMANS; MICROCIRCULATION; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

EID: 0035216055     PISSN: 00946176     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2001-18872     Document Type: Article

References (49)

1. Retrospective description and experimental reconstitution of three different responses of the baboon to lethal E. coli
2. Baboon models of three variants of hemostatic response to inflammatory stimuli
3. The roles of protein C and thrombomodulin in the regulation of blood coagulation
4. Inflammation - The protein C pathway
5. Secretion of tissue-type plasminogen activator and plasminogen activator inhibitor by cultured human endothelial cells: Modulation by thrombin, endotoxin, and histamine
6. Synthesis of a fibrinolytic activator and inhibitor of endothelial cells
7. On the regulation and control of fibrinolysis
8. Free radicals in diabetic endothelial cell dysfunction
9. Effects of endotoxin on lung endothelium
10. Tumor necrosis factor
11. Modulation of endothelial cell hemostatic properties by tumor necrosis factor
12. An endothelial cell surface factor(s) induced in vitro by lipopolysaccharide, interleukin 1, tumor necrosis factor-α increases neutrophil adherence by a CD2-18-dependent mechanism
13. The coagulation cascade. Initiation, maintenance, and regulation
14. Platelet release proteins which inhibit plasminogen activators
15. Detection and partial characterization of an inhibitor of plasminogen activator in human platelets
16. Plasminogen activator inhibitors
17. Expression of tissue factor, thrombomodulin and E-selectin in baboons with lethal E. coli sepsis
18. Identification, cloning and regulation of a novel endothelial cell protein C/activated protein C receptor
19. The endothelial cell protein C receptor: Cell surface expression and direct ligand binding by the soluble receptor
20. The endothelial cell protein C receptor augments protein C activation by the thrombin-thrombomodulin complex
21. Endothelial protein C receptor
22. The protein C pathway: New Insights
23. The roles of protein C and thrombomodulin in the regulation of blood coagulation
24. Tissue factor pathway inhibitor
25. Tissue factor pathway inhibitor - A regulator of tissue factor induced coagulation
26. Stimulation of endothelial cell prostacyclin production by thrombin, trypsin, and ionophore A34187
27. The heparin-antithrombin system: A natural anticoagulant mechanism
28. Thrombin induction of plasminogen activator in cultured endothelial cells
29. Anticoagulant and fibrinolytic activities are promoted, not retarded, in vivo after thrombin generation in the presence of a monoclonal antibody that inhibits activation of protein C
30. Summary of staging, mechanisms, and intervention studies in the baboon model of E. coli sepsis
31. Studies of the natural history and mechanism of the primate (baboon) response to Escherichia coli
32. Sequential renal alterations in septic shock in the primate
33. 100E. coli.)
34. DEGR-factor Xa blocks disseminated intravascular coagulation initiated by E. coli without preventing shock or organ damage
35. 100 septic shock following therapy and antibody to tumor necrosis factor (TNF)
36. Lethal E. coli septic shock is prevented by blocking tissue factor with monoclonal antibody
37. 100 Escherichia coli in the baboon
38. Tissue factor pathway inhibitor (TFPI) reduces mortality from Escherichia coli septic shock
39. Recombinant E. coli derived tissue factor pathway inhibitor reduces coagulopathic and lethal effects in the baboon gram-negative model of septic shock
40. 2+ signals in J82 cells, transfected COS-1 cells, Madin-Darby canine kidney cells and in human endothelial cells induced to synthesize tissue factor
41. 2+ oscillations in Madin-Darby canine kidney cells only when proteolytically active
42. Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon
43. The endothelial cell protein C receptor aids in host defense against Escherichia coli sepsis
44. Immunodepletion of extrinsic pathway inhibitor sensitizes rabbits to endotoxin-induced intravascular coagulation
45. Antithrombin-III prevents the lethal effects of Escherichia coli infusion in baboons
46. Hypoxia/hypoxemia-induced activation of the procoagulant pathways and pathogenesis of ischemia-associated thrombosis
47. Two stage response to endotoxin infusion into normal human subjects: Correlation of blood phagocyte luminescence functional activities with clinical and laboratory markers of the inflammatory response
48. Complement activation with oxidative stress: Role of the lectin complement pathway
49. Prognostic value of protein C concentration in neutropenic patients at high risk of severe septic complications