메뉴 건너뛰기




Volumn 78, Issue 1, 1997, Pages 70-74

The protein C pathway: New insights

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED PROTEIN C; BLOOD CLOTTING FACTOR 5A; CELL RECEPTOR; MEMBRANE RECEPTOR; PROTEIN C; THROMBIN; THROMBOMODULIN;

EID: 0030756899     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0038-1657503     Document Type: Conference Paper
Times cited : (109)

References (36)
  • 1
    • 0024558370 scopus 로고
    • The roles of protein C and thrombomodulin in the regulation of blood coagulation
    • Esmon CT. The roles of protein C and thrombomodulin in the regulation of blood coagulation. J Biol Chem 1989;264:4743-6.
    • (1989) J Biol Chem , vol.264 , pp. 4743-4746
    • Esmon, C.T.1
  • 2
    • 0026409651 scopus 로고
    • Treatment of homozygous protein C deficiency and neonatal purpura fulminans with a purified protein C concentrate
    • Dreyfus M, Magny JF, Bridey F, Schwarz HP, Planché C, Dehan M, Tchernia G. Treatment of homozygous protein C deficiency and neonatal purpura fulminans with a purified protein C concentrate. N Engl J Med 1991;325:1565-8.
    • (1991) N Engl J Med , vol.325 , pp. 1565-1568
    • Dreyfus, M.1    Magny, J.F.2    Bridey, F.3    Schwarz, H.P.4    Planché, C.5    Dehan, M.6    Tchernia, G.7
  • 3
    • 0027965649 scopus 로고
    • Physiological anticoagulation. Resistance to activated protein C and venous thromboembolism
    • Dahlbäck B. Physiological anticoagulation. Resistance to activated protein C and venous thromboembolism. J Clin Invest 1994;94:923-7.
    • (1994) J Clin Invest , vol.94 , pp. 923-927
    • Dahlbäck, B.1
  • 4
    • 0028954459 scopus 로고
    • The first mutation identified in the thrombomodulin gene in a 45-year-old man presenting with thromboembolic disease
    • Ohlin A-K, Marlar RA. The first mutation identified in the thrombomodulin gene in a 45-year-old man presenting with thromboembolic disease. Blood 1995;85(2):330-6.
    • (1995) Blood , vol.85 , Issue.2 , pp. 330-336
    • Ohlin, A.-K.1    Marlar, R.A.2
  • 5
    • 0028876697 scopus 로고
    • Absence of the blood-clotting regulator thrombomodulin causes embryonic lethality in mice before development of a functional cardiovascular system
    • USA
    • Healy AM, Rayburn HB, Rosenberg RD, Weiler H. Absence of the blood-clotting regulator thrombomodulin causes embryonic lethality in mice before development of a functional cardiovascular system. Proc Natl Acad Sci (USA) 1995;92:850-4.
    • (1995) Proc Natl Acad Sci , vol.92 , pp. 850-854
    • Healy, A.M.1    Rayburn, H.B.2    Rosenberg, R.D.3    Weiler, H.4
  • 7
    • 0024556368 scopus 로고
    • Inhibition of platelet-dependent thrombus formation by human activated protein C in a primate model
    • Gruber A, Griffin JH, Harker LA, Hanson SR. Inhibition of platelet-dependent thrombus formation by human activated protein C in a primate model. Blood 1989;73:639-42.
    • (1989) Blood , vol.73 , pp. 639-642
    • Gruber, A.1    Griffin, J.H.2    Harker, L.A.3    Hanson, S.R.4
  • 9
    • 0027186461 scopus 로고
    • Replacement therapy with a purified protein C concentrate during initiation of oral anticoagulation in severe protein C congenital deficiency
    • De Stefano V, Mastrangelo S, Schwarz HP, Pola P, Flore R, Bizzi B, Leone G. Replacement therapy with a purified protein C concentrate during initiation of oral anticoagulation in severe protein C congenital deficiency. Thromb Haemostas 1993;3:247-9.
    • (1993) Thromb Haemostas , vol.3 , pp. 247-249
    • De Stefano, V.1    Mastrangelo, S.2    Schwarz, H.P.3    Pola, P.4    Flore, R.5    Bizzi, B.6    Leone, G.7
  • 14
    • 0027367126 scopus 로고
    • Selective effects of protein C on activation of human monocytes by lipopolysaccharide, interferon-gamma, or PMA: Modulation of effects on CD11b and CD14 but not CD25 or CD54 induction
    • Grey S, Hau H, Salem HH, Hancock WW. Selective effects of protein C on activation of human monocytes by lipopolysaccharide, interferon-gamma, or PMA: Modulation of effects on CD11b and CD14 but not CD25 or CD54 induction. Transplant Proc 1993;25:2913-4.
    • (1993) Transplant Proc , vol.25 , pp. 2913-2914
    • Grey, S.1    Hau, H.2    Salem, H.H.3    Hancock, W.W.4
  • 15
    • 0029873131 scopus 로고    scopus 로고
    • A physiologic anti-inflammatory pathway based on thrombomodulin expression and generation of activated protein C by human mononuclear phagocytes
    • Grey ST, Hancock WW. A physiologic anti-inflammatory pathway based on thrombomodulin expression and generation of activated protein C by human mononuclear phagocytes. J Immunol 1996;156:2256-63.
    • (1996) J Immunol , vol.156 , pp. 2256-2263
    • Grey, S.T.1    Hancock, W.W.2
  • 16
    • 0027397621 scopus 로고
    • Severe acquired protein C deficiency in purpura fulminans associated with disseminated intravascular coagulation: Treatment with protein C concentrate
    • Gerson WT, Dickerman JD, Bovill EG, Golden E. Severe acquired protein C deficiency in purpura fulminans associated with disseminated intravascular coagulation: treatment with protein C concentrate. Pediatrics 1993;91:418-22.
    • (1993) Pediatrics , vol.91 , pp. 418-422
    • Gerson, W.T.1    Dickerman, J.D.2    Bovill, E.G.3    Golden, E.4
  • 17
    • 0028958909 scopus 로고
    • Treatment of purpura fulminans in meningococcemia with protein C concentrate
    • Rivard GE, David M, Farrell C, Schwarz HP. Treatment of purpura fulminans in meningococcemia with protein C concentrate. J Pediatr 1995;126(4):646-52.
    • (1995) J Pediatr , vol.126 , Issue.4 , pp. 646-652
    • Rivard, G.E.1    David, M.2    Farrell, C.3    Schwarz, H.P.4
  • 19
    • 0029119879 scopus 로고
    • An update on clinical and basic aspects of the protein C anticoagulant pathway
    • Esmon CT, Schwarz HP. An update on clinical and basic aspects of the protein C anticoagulant pathway. Trends Cardiovasc Med 1995;5:141-8.
    • (1995) Trends Cardiovasc Med , vol.5 , pp. 141-148
    • Esmon, C.T.1    Schwarz, H.P.2
  • 20
    • 0028226451 scopus 로고
    • Thrombin receptor function and cardiovascular disease
    • Coughlin SR. Thrombin receptor function and cardiovascular disease. Trends Cardiovasc Med 1994;4:77-83.
    • (1994) Trends Cardiovasc Med , vol.4 , pp. 77-83
    • Coughlin, S.R.1
  • 21
    • 0027943163 scopus 로고
    • Identification, cloning and regulation of a novel endothelial cell protein C/activated protein C receptor
    • Fukudome K, Esmon CT. Identification, cloning and regulation of a novel endothelial cell protein C/activated protein C receptor. J Biol Chem 1994;269:26486-91.
    • (1994) J Biol Chem , vol.269 , pp. 26486-26491
    • Fukudome, K.1    Esmon, C.T.2
  • 22
    • 0028109316 scopus 로고
    • High affinity binding sites for activated protein C and protein C on cultured human umbilical vein endothelial cells. Independent of protein S and distinct from known ligands
    • Bangalore N, Drohan WN, Orthner CL. High affinity binding sites for activated protein C and protein C on cultured human umbilical vein endothelial cells. Independent of protein S and distinct from known ligands. Thromb Haemostas 1994;72(3):465-74.
    • (1994) Thromb Haemostas , vol.72 , Issue.3 , pp. 465-474
    • Bangalore, N.1    Drohan, W.N.2    Orthner, C.L.3
  • 23
    • 0030016347 scopus 로고    scopus 로고
    • The endothelial cell protein C receptor: Cell surface expression and direct ligand binding by the soluble receptor
    • Fukudome K, Kurosawa S, Stearns-Kurosawa DJ, He X, Rezaie AR, Esmon CT. The endothelial cell protein C receptor: Cell surface expression and direct ligand binding by the soluble receptor. J Biol Chem 1996;271:17491-8.
    • (1996) J Biol Chem , vol.271 , pp. 17491-17498
    • Fukudome, K.1    Kurosawa, S.2    Stearns-Kurosawa, D.J.3    He, X.4    Rezaie, A.R.5    Esmon, C.T.6
  • 24
    • 1842319845 scopus 로고
    • Assembly and function of the protein C anticoagulant pathway on endothelium
    • New York: Plenum Publishing, Corp.
    • Esmon CT. Simionescu N, Simionescu M, editors.Endothelial cell biology. New York: Plenum Publishing, Corp. 1988; 9, Assembly and function of the protein C anticoagulant pathway on endothelium. p. 191-206.
    • (1988) Endothelial Cell Biology , vol.9 , pp. 191-206
    • Esmon, C.T.1    Simionescu, N.2    Simionescu, M.3
  • 25
  • 26
    • 0029790055 scopus 로고    scopus 로고
    • The endothelial cell protein C receptor augments protein C activation by the thrombin-thrombomodulin complex
    • USA
    • Stearns-Kurosawa DJ, Kurosawa S, Mollica JS, Ferrell GL, Esmon CT. The endothelial cell protein C receptor augments protein C activation by the thrombin-thrombomodulin complex. Proc Natl Acad Sci (USA) 1996;93:10212-6.
    • (1996) Proc Natl Acad Sci , vol.93 , pp. 10212-10216
    • Stearns-Kurosawa, D.J.1    Kurosawa, S.2    Mollica, J.S.3    Ferrell, G.L.4    Esmon, C.T.5
  • 27
    • 0027983980 scopus 로고
    • Structure of a nonadecapeptide of the fifth EGF domain of thrombomodulin complexed with thrombin
    • Mathews II, Padmanabhan KP, Tulinsky A. Structure of a nonadecapeptide of the fifth EGF domain of thrombomodulin complexed with thrombin. Biochemistry 1994;33:13547-52.
    • (1994) Biochemistry , vol.33 , pp. 13547-13552
    • Mathews, I.I.1    Padmanabhan, K.P.2    Tulinsky, A.3
  • 31
    • 0026351350 scopus 로고
    • The active site of thrombin is altered upon binding to thrombomodulin: Two distinct structural changes are detected by fluorescence, but only one correlates with protein C activation
    • Ye J, Esmon NL, Esmon CT, Johnson AE. The active site of thrombin is altered upon binding to thrombomodulin: Two distinct structural changes are detected by fluorescence, but only one correlates with protein C activation. J Biol Chem 1991;266:23016-21.
    • (1991) J Biol Chem , vol.266 , pp. 23016-23021
    • Ye, J.1    Esmon, N.L.2    Esmon, C.T.3    Johnson, A.E.4
  • 35
    • 84888862933 scopus 로고    scopus 로고
    • The newly identified protein C receptor is present primarily on vascular endothelium of large vessels: Implications for the control of the protein C pathway
    • Laszik Z, Esmon CT. The newly identified protein C receptor is present primarily on vascular endothelium of large vessels: Implications for the control of the protein C pathway. [In Press] J Clin Invest 1997.
    • (1997) J Clin Invest
    • Laszik, Z.1    Esmon, C.T.2
  • 36
    • 0009465879 scopus 로고    scopus 로고
    • Upregulation of the message for rodent endothelial cell protein C receptor (EPCR) by endotoxin and thrombin
    • Ding W, Gu J-M, Fukudome K, Laszik Z, Grammas P, Esmon CT. Upregulation of the message for rodent endothelial cell protein C receptor (EPCR) by endotoxin and thrombin. [Abstract] Circulation 1996;94:I694
    • (1996) Circulation , vol.94
    • Ding, W.1    Gu, J.-M.2    Fukudome, K.3    Laszik, Z.4    Grammas, P.5    Esmon, C.T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.