O-acetylsalicylhydroxamic acid, a novel acetylating inhibitor of prostaglandin H2 synthase: Structural and functional characterization of enzyme-inhibitor interactions

Molecular Pharmacology

Volumn 60, Issue 6, 2001, Pages 1407-1413

  Loll, P J ^a   Sharkey, C T ^a   O'Connor, S J ^a   Dooley, C M ^a   O'Brien, E ^a   Devocelle, M ^a   Nolan, K B ^a   Selinsky, B S ^a   Fitzgerald, D J ^a  

^a ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ENZYME INHIBITOR; HYDROXAMIC ACID DERIVATIVE; O ACETYLSALICYLHYDROXAMIC ACID; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR; SERINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG EFFECT; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME INACTIVATION; HYDROGEN BOND; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS INHIBITION; STRUCTURE ACTIVITY RELATION;

EID: 0035213693     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.60.6.1407     Document Type: Article

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