2.3 Å resolution X-ray crystal structure of the bisubstrate analogue inhibitor salicylhydroxamic acid bound to human myeloperoxidase: A model for a prereaction complex with hydrogen peroxide

Biochemistry

Volumn 35, Issue 33, 1996, Pages 10967-10973

  Davey, Curt A ^a   Fenna, Roger E ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME C PEROXIDASE; MYELOPEROXIDASE; SALICYLHYDROXAMIC ACID; HYDROGEN PEROXIDE; PEROXIDASE; SALICYLAMIDE DERIVATIVE;

ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; ENZYME BINDING; HUMAN; HUMAN CELL; HUMAN TISSUE; HYDROGEN BOND; HYDROPHOBICITY; INHIBITION KINETICS; PRIORITY JOURNAL; X RAY ANALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; ENZYME SPECIFICITY; METABOLISM; MOLECULAR GENETICS; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; HUMANS; HYDROGEN BONDING; HYDROGEN PEROXIDE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEROXIDASE; SALICYLAMIDES; SUBSTRATE SPECIFICITY;

EID: 0029664747     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi960577m     Document Type: Article

References (43)

1. Agner, K. (1941) Acta Chem. Scand. 2 (Suppl. 8), 1-62.
2. Andrews, P. C., & Krinsky, N. I. (1981) J. Biol. Chem. 256, 411-418.
3. Ator, M. A., & Ortiz de Montellano, P. R. (1987) J. Biol. Chem. 262, 1542-1551.
4. Ator, M. A., David, S. K., & Ortiz de Montellano, P. R. (1987) J. Biol. Chem. 263, 14954-14960.
5. Belding, M. E., Klebanoff, S. J., & Ray, C. G. (1970) Science 167, 195-196.
6. Brunger, A. J. (1988) J. Mol. Biol. 203, 803-816.
7. Cals, M.-M., Mailliart, P., Brignon, G., Anglade, G., & Dumas, B. R. (1991) Eur. J. Biochem. 198, 733-739.
8. Davies, B., & Edwards, S. W. (1989) Biochem. J. 258, 801-806.
9. Dolphin, D., Forman, A., Borg, D. C., Fajer, J., & Felton, R. (1971) Proc. Natl. Acad. Sci. U.S.A. 68, 614-618.
10. Edwards, S. L., & Poulos, T. L. (1990) J. Biol. Chem. 265, 2588-2595.
11. Edwards, S. L., Poulos, T. L., & Kraut, J. (1984) J. Biol. Chem. 259, 12984-12988.
12. Edwards, S. L., Xuong, N.-h., Hamlin, R. C., & Kraut, J. (1987) Biochemistry 26, 1503-1511.
13. Fenna, R., Zeng, J., & Davey, C. (1995) Arch. Biochem. Biophys. 316, 653-656.
14. Finzel, B. C., Poulos, T. L., & Kraut, J. (1984) J. Biol. Chem. 259, 13027-13036.
15. Harrison, J. E., & Schultz, J. (1976) J. Biol. Chem. 251, 1371-1374.
16. Hori, H., Fenna, R. E., Kimura, S., & Ikeda-Saito, M. (1994) J. Biol. Chem. 269, 8388-8392
17. Ikeda-Saito, M., Shelly, D. A., Lu, L., Booth, K. S., Caughey, W. S., & Kimura, S. (1991) J. Biol. Chem. 266, 3611-3616.
18. Kimura, S., & Yamazaki, I. (1979) Arch. Biochem. Biophys. 198, 580-588.
19. Kimura, S., & Ikeda-Saito, M. (1988) Proteins: Struct., Funct. Genet. 3, 113-120.
20. Kitagawa, T., Hashimoto, S., Teraoka, J., Nakamura, S., Yajima, H., & Hosoya, T. (1983) Biochemistry 22, 2788-2792.
21. Klebanoff, S. J. (1970) Science 169, 1095-1097.
22. Kunishima, N., Fukuyama, K., Matsubara, H., Hatanaka, H., Shibano, Y., & Amachi, T. (1994) J. Mol. Biol. 235, 331-344.
23. La Mar, G. N., Hernandez, G., & de Ropp, J. S. (1992) Biochemistry 31, 9158-9168.
24. Larsen, I. K. (1978) Acta Crystallogr. B34, 962-964
25. Lindner, H. J., Gottlicher, S. (1969) Acta Crystallogr. B25, 832-842.
26. Loo, S., & Erman, J. E. (1975) Biochemistry 14, 3467-3470.
27. Miller, M. A., Shaw, A., & Kraut, J. (1994) Struct. Biol. 1, 524-531.
28. Modi, S., Digambar, V., Mitra, B., & Mitra, S. (1989) Biochim. Biophys. Acta 996, 214-225.
29. Poulos, T. L., & Kraut, J. (1980a) J. Biol. Chem. 255, 8199-8205.
30. Poulos, T. L., & Kraut, J. (1980b) J. Biol. Chem. 255, 10322-10330.
31. Poulos, T. L., Freer, S. T., Alden, R. A., Edwards, S. L., Skogland, U., Takio, K., Eriksson, B., Xuong, N., Yonetani, T., & Kraut, J. (1980) J. Biol. Chem. 255, 575-580.
32. Poulos, T. L., Edwards, S. L., Wariishi, H., & Gold, M. H. (1993) J. Biol. Chem. 268, 4429-4440.
33. Sakurada, J., Takahashi, S., & Hosoya, T. (1986) J. Biol. Chem. 261, 9657-9662.
34. Schonbaum, G. R. (1973) J. Biol. Chem. 248, 502-511.
35. Schonbaum, G. R., & Lo, S. (1972) J. Biol. Chem. 247, 3353-3360.
36. Smulevich, G., Wang, Y., Mauro, J. M., Fishel, L. A., Kraut, J., & Spiro, T. G. (1991) Biochemistry 30, 9546-9558.
37. Stump, R., & Oliver, J. (1985) Biophys. J. 47, 82a.
38. Sutton, B. J., Little, C., Olsen, R. L., & Willassen, N. P. (1988) J. Mol. Biol. 199, 395-396
39. Thanabal, V., de Ropp, J. S., & La Mar, G. N. (1987) J. Am. Chem. Soc. 109, 7516-7525.
40. Vitello, L. B., Erman, J. E., Miller, M. A., Wang, J., & Kraut, J. (1993) Biochemistry 32, 9807-9818.
41. Welinder, K. G. (1985) Eur. J. Biochem. 151, 497-504.
42. Yonetani, T., & Schleyer, H. (1967) J. Biol. Chem. 242, 1974-1979.
43. Zeng, J., & Fenna, R. E. (1992) J. Mol. Biol. 226, 185-207.