Radicicol suppresses transformation and restores tropomyosin-2 expression in both Ras- and MEK-transformed cells without inhibiting the Raf/MEK/ERK signaling cascade

Cell Growth and Differentiation

Volumn 12, Issue 11, 2001, Pages 543-550

  Kim, P N ^a   Jonasch, E ^a   Mosterman, B C ^a   Mier, J W ^a   Janssen, R A J ^a  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; RADICICOL; RAF PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; TROPOMYOSIN;

ANCHORAGE INDEPENDENT GROWTH; ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL PROLIFERATION; CELL SPREADING; CELL TRANSFORMATION; EARLY RESPONSE GENE; EFFECTOR CELL; ENZYME INACTIVATION; GROWTH INHIBITION; MALIGNANT TRANSFORMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RECEPTOR BLOCKING;

3T3 CELLS; ANIMALS; CELL ADHESION; CELL DIVISION; CELL LINE, TRANSFORMED; CELL SIZE; CELL TRANSFORMATION, NEOPLASTIC; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ETS-DOMAIN PROTEIN ELK-1; FIBROBLASTS; GENE EXPRESSION REGULATION, NEOPLASTIC; LACTONES; MACROLIDES; MAP KINASE KINASE 1; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; MUTATION, MISSENSE; ONCOGENE PROTEIN P21(RAS); PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-RAF; RIBOSOMAL PROTEIN S6 KINASES; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTORS; TROPOMYOSIN;

ANIMALIA; CERVUS ELAPHUS;

EID: 0035190492     PISSN: 10449523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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