Radicicol leads to selective depletion of Raf kinase and disrupts K- Ras-activated aberrant signaling pathway

Journal of Biological Chemistry

Volumn 273, Issue 2, 1998, Pages 822-828

  Soga, Shiro ^a   Kozawa, Takako ^a   Narumi, Hiroaki ^a   Akinaga, Shiro ^a   Irie, Kenji ^b   Matsumoto, Kunihiro ^b   Sharma, Sreenath V ^c   Nakano, Hirofumi ^a   Mizukami, Tamio ^a   Hara, Mitsunobu ^a  

^a KYOWA HAKKO KOGYO CO LTD   (Japan)

^b NAGOYA UNIVERSITY   (Japan)

^c UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; RAF PROTEIN;

ANIMAL CELL; ARTICLE; CANCER; CELL PROLIFERATION; ENZYME STABILITY; NONHUMAN; ONCOGENE K RAS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION;

ANIMALS; CELL LINE; ENZYME INHIBITORS; GENES, RAS; HUMANS; LACTONES; MACROLIDES; PANCREATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS C-RAF; RATS; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 0031984520     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.2.822     Document Type: Article

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