Astrocyte-derived monocyte-chemoattractant protein-1 directs the transmigration of leukocytes across a model of the human blood-brain barrier

Journal of Immunology

Volumn 161, Issue 12, 1998, Pages 6896-6903

  Weiss, Jonathan M ^a   Downie, Sherry A ^b   Lyman, William D ^c   Berman, Joan W ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b NEW YORK MEDICAL COLLEGE   (United States)

^c WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; GAMMA INTERFERON; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; MONOCLONAL ANTIBODY; MONOCYTE CHEMOTACTIC PROTEIN 1; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; FETUS; HUMAN; HUMAN CELL; INFLAMMATION; LEUKOCYTE MIGRATION; MONOCYTE; NERVE CELL CULTURE; PRIORITY JOURNAL;

ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; ASTROCYTES; BLOOD-BRAIN BARRIER; CELL COMMUNICATION; CELLS, CULTURED; CHEMOKINE CCL2; CHEMOTAXIS, LEUKOCYTE; COCULTURE TECHNIQUES; E-SELECTIN; ENDOTHELIUM, VASCULAR; FLOW CYTOMETRY; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; INTERFERON-GAMMA, RECOMBINANT; INTERLEUKIN-1; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE ACTIVATION; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR-ALPHA; UMBILICAL VEINS;

EID: 0032534571     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (55)

1. Williams, K. C., E. Ulvestad, and W. F. Hickey. 1994. Immunology of multiple sclerosis. Clin. Neurosci. 2:229.
2. Hofman, F. M., D. R. Hinton, K. Johnson, and J. E. Merrill. 1989. Tumor necrosis factor identified in multiple sclerosis brain. J. Exp. Med. 170:607.
3. Selmaj, K., C. S. Raine, B. Cannella, and C. F. Brosnan. 1991. Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions. J. Clin. Invest. 87:949.
4. Schmidtmayerova, H., H. S. Nottet, G. Nuovo, T. Raabe, C. R. Flanagan, L. Dubrovsky, H. E. Gendelman, A. Cerami, M. Bukrinsky, and B. Sherry. 1996. Human immunodeficiency virus type 1 infection alters chemokine β expression in human monocytes: implications for recruitment of leukocytes into brain and lymph nodes. Proc. Natl. Acad. Sci. USA 93:700.
5. Pulliam, L., R. Gascon, M. Stubblebine, D. McGuire, and M. S. McGrath. 1997. Unique monocyte subset in patients with AIDS dementia. Lancet 349:692.
6. Lee, S. C., W. Liu, D. W. Dickson, C. F. Brosnan, and J. W. Berman. 1993. Cytokine production by human fetal microglia and astrocytes. J. Immunol. 150: 2659.
7. Chung, I. Y., and E. N. Benveniste. 1990. Tumor necrosis factor-α production by astrocytes. J. Immunol. 144:2999.
8. Rollins, B. J. 1997. Chemokines. Blood 90:909.
9. Leonard, E. J., and T. Yoshimura. 1990. Human monocyte chemoattractant protein-1 (MCP-1). Immunol. Today 11:97.
10. Rollins, B. J. 1996. Monocyte chemoattractant protein 1: a potential regulator of monocyte recruitment in inflammatory disease. Mol. Med. Today 2:198.
11. Yla-Herttuala, S., B. A. Lipton, M. E. Rosenfeld, T. Sarkioja, T. Yoshimura, E. J. Leonard, J. L. Witztum, and D. Steinberg. 1988. Expression of monocyte chemoattractant protein-1 in macrophage-rich areas of human and rabbit atherosclerotic lesions. Proc. Natl. Acad. Sci. USA 88:5252.
12. Koch, A. E., S. L. Kunkel, L. A. Harlow, B. Johnson, H. L. Evanoff, G. K. Haines, M. D. Burdick, R. M. Pope, and R. M. Strieter. 1992. Enhanced production of monocyte chemoattractant protein-1 in rheumatoid arthritis. J. Clin. Invest. 90:772.
13. Brown, Z., R. L. Robson, and J. Westwick. 1996. Regulation and expression of chemokines: potential role in glomerulonephritis. J. Leukocyte Biol. 59:75.
14. Conant, K., A. Garzino-Demo, A. Nath, J. C. McArthur, W. Halliday, C. Power, R. C. Gallo, and E. O. Major. 1998. Induction of monocyte chemoattractant protein-1 in HIV-1 Tat-stimulated astrocytes and elevation in AIDS dementia. Proc. Natl. Acad. Sci. USA 95:3117.
15. McManus, C. M., J. W. Berman, F. M. Brett, H. Staunton, M. Farrell, and C. F. Brosnan. 1998. Monocyte chemotactic protein-1 (MCP-1), MCP-2 and MCP-3 expression in multiple sclerosis lesions: an immunohistochemical and in situ hybridization study. J. Neuroimmunol. 86:20.
16. Karpus, W. J., and K. J. Kennedy. 1997. MIP-1α and MCP-1 differentially regulate acute and relapsing autoimmune encephalomyelitis as well as Th1/TH2 lymphocyte differentiation. J. Leukocyte Biol. 62:681.
17. Berman, J. W., M. P. Guida, J. Warren, J. Amat, and C. F. Brosnan. 1996. Localization of monocyte chemoattractant peptide-1 expression in the central nervous system in experimental autoimmune encephalomyelitis and trauma in the rat. J. Immunol. 156:3017.
18. Ransohoff, R. M., T. A. Hamilton, M. Tani, M. H. Stoler, H. E. Shick, J. A. Major, M. L. Estes, D. M. Thomas, and V. K. Tuohy. 1993. Astrocyte expression of mRNA encoding cytokines IP-10 and JE/MCP-1 in experimental autoimmune encephalomyelitis. FASEB J. 7:592.
19. Hulkower, K., C. F. Brosnan, D. A. Aquino, W. Cammer, S. Kulshrestha, M. P. Guida, D. A. Rapoport, and J. W. Berman. 1993. Expression of CSF-1, c-fms and MCP-1 in the central nervous system of rats with experimental allergic encephalomyelitis. J. Immunol. 150:2525.
20. Fuentes, M. E., S. K. Durham, M. R. Swerdel, A. C. Lewin, D. S. Barton, J. R. Megill, R. Bravo, and S. A. Lira. 1995. Controlled recruitment of monocytes and macrophages to specific organs through transgenic expression of monocyte chemoattractant protein-1. J. Immunol. 155:5769.
21. Janzer, R. C. 1993. The blood-brain barrier: cellular basis. J. Inherit. Metab. Dis. 16:639.
22. Williams, K. C., and W. F. Hickey. 1995. Traffic of hematogeneous cells through the central nervous system. Curr. Top. Microbiol. Immunol. 202:221.
23. Rollins, B. J., T. Yoshimura, E. J. Leonard, and J. S. Pober. 1990. Cytokine-activated human endothelial cells synthesize and secrete a monocyte chemoattractant, MCP-1/JE. Am. J. Pathol. 136:1229.
24. Dixit, V. M., S. Green, V. Sarma, L. B. Holzman, F. W. Wolf, K. O'Rourke, P. A. Ward, E. V. Prochownik, and R. M. Marks. 1990. Tumor necrosis factor-α induction of novel gene products in human endothelial cells including a macrophage-specific chemotaxin. J. Biol. Chem. 265:2973.
25. Hurwitz, A. A., W. D. Lyman, and J. W. Berman. 1995. Tumor necrosis factor α and transforming growth factor β up-regulate astrocyte expression of monocyte chemoattractant protein-1. J. Neuroimmunol. 57:193.
26. Randolph, G. J., and M. B. Furie. 1995. A soluble gradient of endogenous monocyte chemoattractant protein-1 promotes the transendothelial migration of monocytes in vitro. J. Immunol. 155:3610.
27. Hurwitz, A. A., J. W. Berman, W. K. Rashbaum, and W. D. Lyman. 1993. Human fetal astrocytes induce the expression of blood-brain barrier specific proteins by autologous endothelial cells. Brain Res. 625:238.
28. Hayashi, Y., M. Nomura, S. Yamagishi, S. Harada, J. Yamashita, and H. Yamamoto. 1997. Induction of various blood-brain barrier properties in non-neural endothelial cells by close apposition to co-cultured astrocytes. Glia 19:13.
29. Lyman, W. D., M. Tricoche, W. C. Hatch, Y. Kress, F. Chiu, and W. K. Rashbaum. 1991. Human fetal central nervous system organotypic cultures. Dev. Brain Res. 60:155.
30. McCarthy, K. D., and J. d. Vellis. 1980. Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. J. Cell Biol. 85:890.
31. Freter, R. R., J. A. Alberta, G. Y. Hwang, A. L. Wrentmore, and C. D. Stiles. 1996. PDGF induction of the immediate-early gene MCP-1 is mediated by NF-κB and a 90-kDa phosphoprotein coactivator. J. Biol. Chem. 271:17417.
32. Boyum, A. 1968. Isolation of mononuclear cells and granulocytes from human blood. Scand. J. Clin. Lab. Invest. 21:77.
33. Calderon, T. M., S. M. Factor, V. B. Hatcher, J. A. Berliner, and J. W. Berman. 1994. An endothelial cell adhesion protein for monocytes recognized by monoclonal antibody IG9: expression in vivo in inflamed human vessels and atherosclerotic human and Watanabe rabbit vessels. Lab. Invest. 70:836.
34. Carr, M. W., S. J. Roth, E. Luther, S. S. Rose, and T. A. Springer. 1994. Monocyte chemoattractant protein 1 acts as a T-lymphocyte chemoattractant. Proc. Natl. Acad. Sci. USA 91:3652.
35. Weiss, J. M., and J. W. Berman. 1998. Astrocyte expression of monocyte chemoattractant protein-1 is differentially regulated by transforming growth factor-β. J. Neuroimmunol. In press.
36. Ziegler, S. F., F. Ramsdell, and M. R. Alderson. 1994. The activation antigen CD69. Stem Cells 12:456.
37. Takahashi, M., J. Masuyama, U. Ikeda, T. Kasahara, S. Kitagawa, Y. Takahashi, K. Shimada, and S. Kano. 1995. Induction of monocyte chemoattractant protein-1 synthesis in human monocytes during transendothelial migration in vitro. Circ. Res. 76:750.
38. McManus, C. M., C. F. Brosnan, and J. W. Berman. 1998. Cytokine induction of MIP-1α and MIP-1β in human fetal microglia. J. Immunol. 160:1449.
39. Persidsky, Y., M. Stins, D. Way, M. H. Witte, M. Weinand, K. S. Kim, P. Bock, H. E. Gendelman, and M. Fiala. 1997. A model for monocyte migration through the blood-brain barrier during HIV-1 encephalitis. J. Immunol. 158:3499.
40. Birdsall, H. H., J. Trial, H. J. Lin, D. M. Green, G. W. Sorrentino, E. B. Siwak, A. L. d. Jong, and R. D. Rossen. 1997. Transendothelial migration of lymphocytes from HIV-1-infected donors. J. Immunol. 158:5968.
41. Wyss-Coray, T., P. Borrow, M. J. Brooker, and L. Mucke. 1997. Astroglial over-production of TGF-β1 enhances inflammatory central nervous system disease in transgenic mice. J. Neuroimmunol. 77:45.
42. Racke, M. K., S. Sriram, J. Carlino, B. Cannella, C. S. Raine, and D. E. McFarlin. 1993. Long-term treatment of chronic relapsing experimental allergic encephalomyelitis by transforming growth factor-β2. J. Neuroimmunol. 46:175.
43. Santambrogio, L., G. M. Hochwald, B. Saxena, C. H. Leu, J. E. Martz, J. A. Carlino, N. H. Ruddle, M. A. Palladino, L. I. Gold, and G. J. Thorbecke. 1993. Studies on the mechanism by which transforming growth factor-β protects against allergic encephalomyelitis: antagonism between TGF-β and tumor necrosis factor. J. Immunol. 151:1116.
44. Wahl, S. M. 1994. Transforming growth factor β: the good, the bad, and the ugly. J. Exp. Med. 180:1587.
45. Cannella, B., and C. S. Raine. 1995. The adhesion molecule and cytokine profile of multiple sclerosis lesions. Ann. Neurol. 37:424.
46. Washington, R., J. Burton, R. F. Todd, W. Newman, L. Dragovic, and P. Dore-Duffy. 1994. Expression of immunologically relevant endothelial cell activation antigens on isolated central nervous system microvessels from patients with multiple sclerosis. Ann. Neurol. 35:89.
47. Nottet, H. S. L. M., Y. Persidsky, V. G. Sasseville, A. N. Nukuna, P. Bock, Q. Zhai, L. R. Sharer, R. D. McComb, S. Swindells, C. Soderland, and H. E. Gendelman. 1996. Mechanisms for the transendothelial migration of HIV-1 infected monocytes into brain. J. Immunol. 156:1284.
48. Seilhean, D., A. Dzia-Lepfoundzou, V. Sazdovitch, B. Cannella, C. S. Raine, C. Katlama, F. Bricaire, C. Duyckaerts, and J. J. Hauw. 1997. Astrocytic adhesion molecules are increased in HIV-1 associated cognitive/motor complex. Neuropathol. Appl. Neurobiol. 23:83.
49. 1 integrin. Nature 356:63.
50. Selmaj, K., A. Walczak, M. Mycko, T. Berkowicz, T. Kohno, and C. S. Raine. 1998. Suppression of experimental autoimmune encephalomyelitis with a TNF binding protein (TNFbp) correlates with down-regulation of VCAM-1/VLA-4. Eur. J. Immunol. 28:2035.
51. 1 integrin interactions. Am. J. Pathol. 144:27.
52. Hakkert, B. C., T. W. Kuijpers, J. F. Leeuwenberg, J. A. vanMourik, and D. Roos. 1991. Neutrophil and monocyte adherence to and migration across monolayers of cytokine-activated endothelial cells: the contribution of CD18, ELAM-1 and VLA-4. Blood 78:2721.
53. Andrew, D. P., J. P. Spellberg, H. Takimoto, R. Schmits, T. W. Mak, and M. M. Zukowski. 1998. Transendothelial migration and trafficking of leukocytes in LFA-1-deficient mice. Eur. J. Immunol. 28:1959.
54. Elices, M. J., L. Osborn, Y. Takada, C. Crouse, S. Luhowskyj, M. E. Hemler, and R. R. Lobb. 1990. VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site. Cell 60:577.
55. Weiss, J. M., C. A. Cuff, and J. W. Berman. 1998. TGF-β down-modulates cytokine-induced monocyte chemoattractant protein (MCP)-1 expression in human endothelial cells: a role for TGF-β in the modulation of TNF receptor expression. Endothelium. In press.