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Volumn 44, Issue 1, 1998, Pages 35-46

Effective treatment of models of multiple sclerosis by matrix metalloproteinase inhibitors

Author keywords

[No Author keywords available]

Indexed keywords

BATIMASTAT; BB 1101; BB 2275; INTERLEUKIN 4; MATRIX METALLOPROTEINASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 0031902651     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.410440110     Document Type: Article
Times cited : (111)

References (62)
  • 1
    • 0001791736 scopus 로고    scopus 로고
    • Clinical features of multiple sclerosis
    • Raine CS, McFarland HF, Tourtellotte WW, eds. London: Chapman and Hall
    • Whitaker JN, Mitchell GW. Clinical features of multiple sclerosis. In: Raine CS, McFarland HF, Tourtellotte WW, eds. Multiple sclerosis: clinical and pathogenetic basis. London: Chapman and Hall, 1997:3-19
    • (1997) Multiple Sclerosis: Clinical and Pathogenetic Basis , pp. 3-19
    • Whitaker, J.N.1    Mitchell, G.W.2
  • 2
    • 0021592979 scopus 로고
    • Biology of disease: The analysis of autoimmune demyelination: Its impact on multiple sclerosis
    • Raine CS. Biology of disease: the analysis of autoimmune demyelination: its impact on multiple sclerosis. Lab Invest 1984;50:608-635
    • (1984) Lab Invest , vol.50 , pp. 608-635
    • Raine, C.S.1
  • 4
    • 0029939467 scopus 로고    scopus 로고
    • Multiple sclerosis: A coordinated immunological attack against myelin in the central nervous system
    • Steinman L. Multiple sclerosis: a coordinated immunological attack against myelin in the central nervous system. Cell 1996; 85:299-302
    • (1996) Cell , vol.85 , pp. 299-302
    • Steinman, L.1
  • 5
    • 0027418515 scopus 로고
    • Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. I. Clinical results of a mulricenter, randomized, double-blind, placebo-controlled trial
    • The IFNB MS Study Group. Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. I. Clinical results of a mulricenter, randomized, double-blind, placebo-controlled trial. Neurology 1993;43:655-666
    • (1993) Neurology , vol.43 , pp. 655-666
  • 6
    • 0029082566 scopus 로고
    • Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis: Results of a phase III multicenter, double-blind placebo-controlled trial
    • Johnson KP, Brooks BR, Cohen JA, et al. Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis: results of a phase III multicenter, double-blind placebo-controlled trial. Neurology 1995;45:1268-1276
    • (1995) Neurology , vol.45 , pp. 1268-1276
    • Johnson, K.P.1    Brooks, B.R.2    Cohen, J.A.3
  • 8
    • 0021328623 scopus 로고
    • Adoptive transfer of myelin basic protein-sensitized T cells produces chronic relapsing demyelinating disease in mice
    • Mokhtarian F, McFarlin DE, Raine CS. Adoptive transfer of myelin basic protein-sensitized T cells produces chronic relapsing demyelinating disease in mice. Nature 1984;309:356-358
    • (1984) Nature , vol.309 , pp. 356-358
    • Mokhtarian, F.1    McFarlin, D.E.2    Raine, C.S.3
  • 9
    • 0028872064 scopus 로고
    • Two models of multiple sclerosis: Experimental allergic encephalomyelitis (EAE) and Theiler's murine encephalomyelitis virus (TMEV) infection. A pathological and immunological comparison
    • Dal Canto MC, Melvold RW, Kim BS, Miller SD. Two models of multiple sclerosis: experimental allergic encephalomyelitis (EAE) and Theiler's murine encephalomyelitis virus (TMEV) infection. A pathological and immunological comparison. Microsc Res Tech 1995;32:215-229
    • (1995) Microsc Res Tech , vol.32 , pp. 215-229
    • Dal Canto, M.C.1    Melvold, R.W.2    Kim, B.S.3    Miller, S.D.4
  • 10
    • 0029079836 scopus 로고
    • A review of T cell receptors in multiple sclerosis: Clonal expansion and persistence of human T cells specific for an immunodominanr myelin basic protein peptide
    • Wucherpfennig KW, Hafler DA. A review of T cell receptors in multiple sclerosis: clonal expansion and persistence of human T cells specific for an immunodominanr myelin basic protein peptide. Ann NY Acad Sci 1995;756:241-258
    • (1995) Ann NY Acad Sci , vol.756 , pp. 241-258
    • Wucherpfennig, K.W.1    Hafler, D.A.2
  • 11
    • 0030800188 scopus 로고    scopus 로고
    • The Norton Lecture: A review of the oligodendrocyte in the multiple sclerosis lesion
    • Raine CS. The Norton Lecture: a review of the oligodendrocyte in the multiple sclerosis lesion. J Neuroimmunol 1997;77:135-152
    • (1997) J Neuroimmunol , vol.77 , pp. 135-152
    • Raine, C.S.1
  • 12
    • 0024366885 scopus 로고
    • Tumor necrosis factor identified in multiple sclerosis brain
    • Hofman FM, Hinton DR, Johnson K, Merrill JE. Tumor necrosis factor identified in multiple sclerosis brain. J Exp Med 1989;170:607-612
    • (1989) J Exp Med , vol.170 , pp. 607-612
    • Hofman, F.M.1    Hinton, D.R.2    Johnson, K.3    Merrill, J.E.4
  • 13
    • 0025773147 scopus 로고
    • Association between TNFα and disease progression in patients with mulriple sclerosis
    • Sharief MK, Hentges R. Association between TNFα and disease progression in patients with mulriple sclerosis. N Engl J Med 1991;325:467-472
    • (1991) N Engl J Med , vol.325 , pp. 467-472
    • Sharief, M.K.1    Hentges, R.2
  • 14
    • 0025852567 scopus 로고
    • Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions
    • Selmaj K, Raine CS, Cannella B, Brosnan CF. Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions. J Clin Invest 1991;87:949-954
    • (1991) J Clin Invest , vol.87 , pp. 949-954
    • Selmaj, K.1    Raine, C.S.2    Cannella, B.3    Brosnan, C.F.4
  • 15
    • 0025000863 scopus 로고
    • An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental autoimmune encephalomyelitis
    • Ruddle NH, Bergman CM, McGrath KM, et al. An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental autoimmune encephalomyelitis. J Exp Med 1990; 172:1193-1200
    • (1990) J Exp Med , vol.172 , pp. 1193-1200
    • Ruddle, N.H.1    Bergman, C.M.2    McGrath, K.M.3
  • 16
    • 0026094706 scopus 로고
    • Anti-TNF therapy abrogares autoimmune demyelination
    • Selmaj K, Raine CS, Cross AH. Anti-TNF therapy abrogares autoimmune demyelination. Ann Neurol 1991;30:694-700
    • (1991) Ann Neurol , vol.30 , pp. 694-700
    • Selmaj, K.1    Raine, C.S.2    Cross, A.H.3
  • 17
    • 0025906424 scopus 로고
    • Differential tumor necrosis factor alpha expression by astrocytes from experimental allergic encephalomyelitis-susceptible and -resistant rat strains
    • Chung IY, Norris JG, Benveniste EN. Differential tumor necrosis factor alpha expression by astrocytes from experimental allergic encephalomyelitis-susceptible and -resistant rat strains. J Exp Med 1991:173:801-811
    • (1991) J Exp Med , vol.173 , pp. 801-811
    • Chung, I.Y.1    Norris, J.G.2    Benveniste, E.N.3
  • 18
    • 0028912608 scopus 로고
    • Prevention of autoimmune demyelination in non-human primates by a cAMP-specific phosphodiesterase inhibitor
    • Genain CP, Roberts T, Davis RL, et al. Prevention of autoimmune demyelination in non-human primates by a cAMP-specific phosphodiesterase inhibitor. Ptoc Natl Acad Sci USA 1995;92:3601-3605
    • (1995) Ptoc Natl Acad Sci USA , vol.92 , pp. 3601-3605
    • Genain, C.P.1    Roberts, T.2    Davis, R.L.3
  • 19
    • 0028955945 scopus 로고
    • The antidepressant rolipram suppresses cytokine production and prevents autoimmune encephalomyelitis
    • Sommer N, Loeschmann PA, Northoff GH, et al. The antidepressant rolipram suppresses cytokine production and prevents autoimmune encephalomyelitis. Nat Med 1995;1:244-248
    • (1995) Nat Med , vol.1 , pp. 244-248
    • Sommer, N.1    Loeschmann, P.A.2    Northoff, G.H.3
  • 20
    • 0028864801 scopus 로고
    • Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system specific expression of tumor necrosis factor a
    • Probert L, Akassoglu K, Pasparakis M, et al. Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system specific expression of tumor necrosis factor a. Proc Natl Acad Sci USA 1995;92:11294-11298
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 11294-11298
    • Probert, L.1    Akassoglu, K.2    Pasparakis, M.3
  • 21
    • 0023281068 scopus 로고
    • Production of cytotoxic factor for oligodendrocytes by stimulated astrocytes
    • Robbins DS, Shirazi Y, Drysdale BE, et al. Production of cytotoxic factor for oligodendrocytes by stimulated astrocytes. J Immunol 1987;139:2593-2597
    • (1987) J Immunol , vol.139 , pp. 2593-2597
    • Robbins, D.S.1    Shirazi, Y.2    Drysdale, B.E.3
  • 22
    • 0023904746 scopus 로고
    • Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro
    • Selmaj KW, Raine CS. Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro. Ann Neurol 1988;23: 339-346
    • (1988) Ann Neurol , vol.23 , pp. 339-346
    • Selmaj, K.W.1    Raine, C.S.2
  • 23
    • 0018148235 scopus 로고
    • Degradation of basic protein in myelin by neutral proteases secreted by stimulated macrophages: A possible mechanism of inflammatory demyelination
    • Cammer W, Bloom BR, Norton WT, Gordon S. Degradation of basic protein in myelin by neutral proteases secreted by stimulated macrophages: a possible mechanism of inflammatory demyelination. Proc Natl Acad Sci USA 1978;75:1554-1558
    • (1978) Proc Natl Acad Sci USA , vol.75 , pp. 1554-1558
    • Cammer, W.1    Bloom, B.R.2    Norton, W.T.3    Gordon, S.4
  • 24
    • 0018189526 scopus 로고
    • Proteolytic enzyme activity of blood leukocytes and cerebrospinal fluid in multiple sclerosis
    • Cuzner ML, Davison AN, Rudge P. Proteolytic enzyme activity of blood leukocytes and cerebrospinal fluid in multiple sclerosis. Ann Neurol 1978;4:337-344
    • (1978) Ann Neurol , vol.4 , pp. 337-344
    • Cuzner, M.L.1    Davison, A.N.2    Rudge, P.3
  • 25
    • 0018879480 scopus 로고
    • Proteinase inhibitors suppress the development of experimental allergic encephalomyelitis
    • Brosnan CF, Cammer W, Norton WT, Bloom BR. Proteinase inhibitors suppress the development of experimental allergic encephalomyelitis. Nature 1980;285:235-237
    • (1980) Nature , vol.285 , pp. 235-237
    • Brosnan, C.F.1    Cammer, W.2    Norton, W.T.3    Bloom, B.R.4
  • 26
    • 0027368518 scopus 로고
    • Gelatinase B is present in the cerebrospinal fluid during experimental allergic encephalomyelitis and cleaves myelin basic protein
    • Gijbels K, Proost P, Masure S, et al. Gelatinase B is present in the cerebrospinal fluid during experimental allergic encephalomyelitis and cleaves myelin basic protein. J Neurosci Res 1993; 36:432-440
    • (1993) J Neurosci Res , vol.36 , pp. 432-440
    • Gijbels, K.1    Proost, P.2    Masure, S.3
  • 27
    • 0030469753 scopus 로고    scopus 로고
    • Multiple sclerosis: Fas signaling in oligodendrocyte cell death
    • D'Souza SD, Bonetti B, Balasingam V, et al. Multiple sclerosis: Fas signaling in oligodendrocyte cell death. J Exp Med 1996; 184:2361-2370
    • (1996) J Exp Med , vol.184 , pp. 2361-2370
    • D'Souza, S.D.1    Bonetti, B.2    Balasingam, V.3
  • 28
    • 0028466705 scopus 로고
    • Protection against a lethal dose of endotoxin by an inhibitor of tumor necrosis factor processing
    • Mohler KM, Sleath PR, Fitzner JN, et al. Protection against a lethal dose of endotoxin by an inhibitor of tumor necrosis factor processing. Nature 1994;370:218-220
    • (1994) Nature , vol.370 , pp. 218-220
    • Mohler, K.M.1    Sleath, P.R.2    Fitzner, J.N.3
  • 29
    • 0028485654 scopus 로고
    • Processing of tumor necrosis factor and precursor by metalloproteinases
    • Gearing AJH, Beckett P, Christodoulou M, et al. Processing of tumor necrosis factor and precursor by metalloproteinases. Nature 1994;370:555-557
    • (1994) Nature , vol.370 , pp. 555-557
    • Gearing, A.J.H.1    Beckett, P.2    Christodoulou, M.3
  • 30
    • 0028483534 scopus 로고
    • Regulation of tumor necrosis factor alpha processing by a metalloproteinase inhibitor
    • McGeehan GM, Becherer JD, Bast RC, et al. Regulation of tumor necrosis factor alpha processing by a metalloproteinase inhibitor. Nature 1994;370:558-561
    • (1994) Nature , vol.370 , pp. 558-561
    • McGeehan, G.M.1    Becherer, J.D.2    Bast, R.C.3
  • 31
    • 0029129643 scopus 로고
    • Regulation of cell surface Apo-1/Fas (CD 95) ligand expression by metalloproteases
    • Mariani SM, Matiba B, Baeumler C, Krammer PH. Regulation of cell surface Apo-1/Fas (CD 95) ligand expression by metalloproteases. Eur J Immunol 1994;25:2303-2307
    • (1994) Eur J Immunol , vol.25 , pp. 2303-2307
    • Mariani, S.M.1    Matiba, B.2    Baeumler, C.3    Krammer, P.H.4
  • 32
    • 0028116618 scopus 로고
    • Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease
    • Racke MK, Bonomo A, Scott DE, et al. Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease. J Exp Med 1994;180:1961-1966
    • (1994) J Exp Med , vol.180 , pp. 1961-1966
    • Racke, M.K.1    Bonomo, A.2    Scott, D.E.3
  • 33
    • 0030918701 scopus 로고    scopus 로고
    • Local delivery of interleukin 4 by retrovirus-transduced T lymphocytes ameliorates experimental autoimmune encephalomyelitis
    • Shaw MK, Lorens JB, Dhawan A, et al. Local delivery of interleukin 4 by retrovirus-transduced T lymphocytes ameliorates experimental autoimmune encephalomyelitis. J Exp Med 1997; 185:1711-1714
    • (1997) J Exp Med , vol.185 , pp. 1711-1714
    • Shaw, M.K.1    Lorens, J.B.2    Dhawan, A.3
  • 34
    • 0029742433 scopus 로고    scopus 로고
    • IL-10 fails to abrogate experimental autoimmune encephalomyelitis
    • Cannella B, Gao YL, Brosnan CF, Raine CS. IL-10 fails to abrogate experimental autoimmune encephalomyelitis. J Neurosci Res 1996;45:735-746
    • (1996) J Neurosci Res , vol.45 , pp. 735-746
    • Cannella, B.1    Gao, Y.L.2    Brosnan, C.F.3    Raine, C.S.4
  • 35
    • 0021720673 scopus 로고
    • Adoptively transferred chronic relapsing experimental autoimmune encephalomyelitis in the mouse. Neuropathologic analysis
    • Raine CS, Mokhtarian F, McFarlin DE. Adoptively transferred chronic relapsing experimental autoimmune encephalomyelitis in the mouse. Neuropathologic analysis. Lab Invest 1984:51: 534-546
    • (1984) Lab Invest , vol.51 , pp. 534-546
    • Raine, C.S.1    Mokhtarian, F.2    McFarlin, D.E.3
  • 36
    • 0030273614 scopus 로고    scopus 로고
    • GFAP is necessary for the integrity of CNS white matter architecture and long-term maintenance of myelination
    • Liedtke W, Edelmann-W, Bieri PL, et al. GFAP is necessary for the integrity of CNS white matter architecture and long-term maintenance of myelination. Neuron 1996;17:607-615
    • (1996) Neuron , vol.17 , pp. 607-615
    • Liedtke, W.1    Edelmann, W.2    Bieri, P.L.3
  • 37
    • 0029819746 scopus 로고    scopus 로고
    • Nerve growth factor and neurotrophin-3 differentially regulate the proliferation and survival of developing rat brain oligodendrocytes
    • Cohen RI, Marmur R, Norton WT, et al. Nerve growth factor and neurotrophin-3 differentially regulate the proliferation and survival of developing rat brain oligodendrocytes. J Neurosci 1996;16:6433-6442
    • (1996) J Neurosci , vol.16 , pp. 6433-6442
    • Cohen, R.I.1    Marmur, R.2    Norton, W.T.3
  • 38
    • 0028584329 scopus 로고
    • A comparison of methods for RNA extraction from lymphocytes for RT-PCR
    • Liedtke W, Battistini L, Brosnan CF, Raine CS. A comparison of methods for RNA extraction from lymphocytes for RT-PCR. PCR Methods Appl 1994;4:185-187
    • (1994) PCR Methods Appl , vol.4 , pp. 185-187
    • Liedtke, W.1    Battistini, L.2    Brosnan, C.F.3    Raine, C.S.4
  • 39
    • 0028039312 scopus 로고
    • Advanced methods in PCR product detection
    • Lazar JG. Advanced methods in PCR product detection. PCR Methods Appl 1994;4:S1-S14
    • (1994) PCR Methods Appl , vol.4
    • Lazar, J.G.1
  • 40
    • 0027461543 scopus 로고
    • Synthesis of RNA probes by the direct in vitro transcription on PCR-generated DNA templates
    • Urrutia R, McNiven MA, Kachar B. Synthesis of RNA probes by the direct in vitro transcription on PCR-generated DNA templates. J Biochem Biophys Methods 1993;26:113-120
    • (1993) J Biochem Biophys Methods , vol.26 , pp. 113-120
    • Urrutia, R.1    McNiven, M.A.2    Kachar, B.3
  • 41
    • 0002238917 scopus 로고
    • RT-PCR and mRNA quantitation
    • Mullis KB, Ferre F, Gibbs RA, eds. Boston: Birkhaeuser
    • Chelly J, Kahn A. RT-PCR and mRNA quantitation. In: Mullis KB, Ferre F, Gibbs RA, eds. PCR - polymerase chain reaction. Boston: Birkhaeuser, 1994:97-110
    • (1994) PCR - Polymerase Chain Reaction , pp. 97-110
    • Chelly, J.1    Kahn, A.2
  • 42
    • 0028120895 scopus 로고
    • Structural requirements for binding of an immunodominant myelin basic protein peptide to DR2 isotypes and for its recognition by human T cell clones
    • Wucherpfennig KW, Sette A, Southwood S, et al. Structural requirements for binding of an immunodominant myelin basic protein peptide to DR2 isotypes and for its recognition by human T cell clones. J Exp Med 1994;179:279-290
    • (1994) J Exp Med , vol.179 , pp. 279-290
    • Wucherpfennig, K.W.1    Sette, A.2    Southwood, S.3
  • 43
    • 0028238201 scopus 로고
    • Clonal expansion and persistence of human T cells specific for an immunodominant myelin basic protein peptide
    • Wucherpfennig KW, Zhang J, Witek C, et al. Clonal expansion and persistence of human T cells specific for an immunodominant myelin basic protein peptide. J Immunol 1994;152:5581-5592
    • (1994) J Immunol , vol.152 , pp. 5581-5592
    • Wucherpfennig, K.W.1    Zhang, J.2    Witek, C.3
  • 44
    • 0030248444 scopus 로고    scopus 로고
    • Delayed-type hypersensitivity lesions in the central nervous system are prevented by inhibitots of matrix metalloproteinases
    • Matyszak MK, Perry VH. Delayed-type hypersensitivity lesions in the central nervous system are prevented by inhibitots of matrix metalloproteinases. J Neuroimmunol 1996;69:141-149
    • (1996) J Neuroimmunol , vol.69 , pp. 141-149
    • Matyszak, M.K.1    Perry, V.H.2
  • 45
    • 10744226623 scopus 로고    scopus 로고
    • Matrix metalloproteinase expression during experimental autoimmune encephalomyelitis and effects of a combined matrix metalloproteinase and tumor necrosis factor a inhibitor
    • Clements JM, Cossins JA, Wells GMA, et al. Matrix metalloproteinase expression during experimental autoimmune encephalomyelitis and effects of a combined matrix metalloproteinase and tumor necrosis factor a inhibitor. J Neuroimmunol 1997; 74:85-94
    • (1997) J Neuroimmunol , vol.74 , pp. 85-94
    • Clements, J.M.1    Cossins, J.A.2    Wells, G.M.A.3
  • 46
    • 0019468319 scopus 로고
    • The effects of macrophage depletion on the clinical and pathological expression of experimental autoimmune encephalomyelitis
    • Brosnan CF, Bornstein MB, Bloom BR. The effects of macrophage depletion on the clinical and pathological expression of experimental autoimmune encephalomyelitis. J Immunol 1981; 126:614-620
    • (1981) J Immunol , vol.126 , pp. 614-620
    • Brosnan, C.F.1    Bornstein, M.B.2    Bloom, B.R.3
  • 47
    • 0030738366 scopus 로고    scopus 로고
    • Multiple sclerosis: Oligodendrocytes display cell death-related molecules in situ but do not undergo apoptosis
    • Bonetti B, Raine CS. Multiple sclerosis: oligodendrocytes display cell death-related molecules in situ but do not undergo apoptosis. Ann Neurol 1997;42:74-84
    • (1997) Ann Neurol , vol.42 , pp. 74-84
    • Bonetti, B.1    Raine, C.S.2
  • 48
    • 0025817888 scopus 로고
    • Apoptosis in the nervous system in experimental allergic encephalomyelitis
    • Pender MP, Nguyen KB, McCombe PA, Kerr JF. Apoptosis in the nervous system in experimental allergic encephalomyelitis. J Neurol Sci 1991;104:81-87
    • (1991) J Neurol Sci , vol.104 , pp. 81-87
    • Pender, M.P.1    Nguyen, K.B.2    McCombe, P.A.3    Kerr, J.F.4
  • 49
    • 0027773017 scopus 로고
    • Apoptosis of T lymphocytes in experimental autoimmune encephalomyelitis: Evidence for programmed cell death as a mechanism to control inflammation in the brain
    • Schmied M, Breitschopf H, Gold R, et al. Apoptosis of T lymphocytes in experimental autoimmune encephalomyelitis: evidence for programmed cell death as a mechanism to control inflammation in the brain. Am J Pathol 1993;143:446-452
    • (1993) Am J Pathol , vol.143 , pp. 446-452
    • Schmied, M.1    Breitschopf, H.2    Gold, R.3
  • 50
    • 0031227661 scopus 로고    scopus 로고
    • Human autoreactive and foreign antigen-specific T cells resist apoptosis induced by soluble recombinant CD95 ligand
    • Zipp F, Martin R, Lichtenfels R, et al. Human autoreactive and foreign antigen-specific T cells resist apoptosis induced by soluble recombinant CD95 ligand. J Immunol 1997;159:2108-2115
    • (1997) J Immunol , vol.159 , pp. 2108-2115
    • Zipp, F.1    Martin, R.2    Lichtenfels, R.3
  • 51
    • 84993913357 scopus 로고
    • Multiple sclerosis: TNF revisited, with promise
    • Raine CS. Multiple sclerosis: TNF revisited, with promise. Nat Med 1995;1:211-214
    • (1995) Nat Med , vol.1 , pp. 211-214
    • Raine, C.S.1
  • 52
    • 0029417152 scopus 로고
    • TNF-alpha- and IFN-gamma-mediated signal transduction pathways: Effects on glial cell gene expression and function
    • Benveniste EN, Benos DJ. TNF-alpha- and IFN-gamma-mediated signal transduction pathways: effects on glial cell gene expression and function. FASEB J 1995;9:1577-1584
    • (1995) FASEB J , vol.9 , pp. 1577-1584
    • Benveniste, E.N.1    Benos, D.J.2
  • 53
    • 0026771135 scopus 로고
    • Tumor necrosis factor (TNF-alpha) and lymphotoxin (TNF-beta)
    • Ruddle NH. Tumor necrosis factor (TNF-alpha) and lymphotoxin (TNF-beta). Curr Opin Immunol 1992;4:327-332
    • (1992) Curr Opin Immunol , vol.4 , pp. 327-332
    • Ruddle, N.H.1
  • 54
    • 0027944171 scopus 로고
    • Reversal of experimental autoimmune encephalomyelitis with a hydroxamate inhibitor of matrix metalloproteinases
    • Gijbels K, Galardy RE, Steinman L. Reversal of experimental autoimmune encephalomyelitis with a hydroxamate inhibitor of matrix metalloproteinases. J Clin Invest 1992;94:2177-2182
    • (1992) J Clin Invest , vol.94 , pp. 2177-2182
    • Gijbels, K.1    Galardy, R.E.2    Steinman, L.3
  • 55
    • 0029041446 scopus 로고
    • T cell gelatinases mediate basement membrane transmigration in vitro
    • Leppert D, Waubant E, Galardy R, et al. T cell gelatinases mediate basement membrane transmigration in vitro. J Immunol 1995;154:4379-4389
    • (1995) J Immunol , vol.154 , pp. 4379-4389
    • Leppert, D.1    Waubant, E.2    Galardy, R.3
  • 56
    • 0029046464 scopus 로고
    • Suppression of experimental allergic encephalomyelitis in the Lewis rat by the matrix metalloproteinase inhibitor Ro31-9790
    • Hewson AK, Smith T, Leonard JP, Cuzner ML. Suppression of experimental allergic encephalomyelitis in the Lewis rat by the matrix metalloproteinase inhibitor Ro31-9790. Inflamm Res 1995;44:345-349
    • (1995) Inflamm Res , vol.44 , pp. 345-349
    • Hewson, A.K.1    Smith, T.2    Leonard, J.P.3    Cuzner, M.L.4
  • 57
    • 0029585742 scopus 로고
    • Prevention of acute autoimmune encephalomyelitis and abrogation of relapses in murine models of multiple sclerosis by the protease inhibitor D-penicillamine
    • Norga K, Paemen L, Masure S, et al. Prevention of acute autoimmune encephalomyelitis and abrogation of relapses in murine models of multiple sclerosis by the protease inhibitor D-penicillamine. Inflamm Res 1995;44:529-534
    • (1995) Inflamm Res , vol.44 , pp. 529-534
    • Norga, K.1    Paemen, L.2    Masure, S.3
  • 58
    • 0026442957 scopus 로고
    • Gelatinase in the cerebrospinal fluid of patients with multiple sclerosis and other inflammatory neurological disorders
    • Gijbels K, Masure S, Carton H, Opdenakker G. Gelatinase in the cerebrospinal fluid of patients with multiple sclerosis and other inflammatory neurological disorders. J Neuroimmunol 1992;41:29-34
    • (1992) J Neuroimmunol , vol.41 , pp. 29-34
    • Gijbels, K.1    Masure, S.2    Carton, H.3    Opdenakker, G.4
  • 59
    • 0029867128 scopus 로고    scopus 로고
    • Matrix metalloproteinases in the normal human central nervous system, microglial nodules, and multiple sclerosis lesions
    • Maeda A, Sobel RA. Matrix metalloproteinases in the normal human central nervous system, microglial nodules, and multiple sclerosis lesions. J Neuropathol Exp Neurol 1996;55:300-309
    • (1996) J Neuropathol Exp Neurol , vol.55 , pp. 300-309
    • Maeda, A.1    Sobel, R.A.2
  • 60
    • 0029907622 scopus 로고    scopus 로고
    • The expression of tissue type plasminogen activator, matrix metalloproteinase inhibitors and endogenous inhibitors in the central nervous system in multiple sclerosis: Comparison of stages in lesion evolution
    • Cuzner ML, Gveric D, Strand C, et al. The expression of tissue type plasminogen activator, matrix metalloproteinase inhibitors and endogenous inhibitors in the central nervous system in multiple sclerosis: comparison of stages in lesion evolution. J Neuropathol Exp Neurol 1996;55:1194-1204
    • (1996) J Neuropathol Exp Neurol , vol.55 , pp. 1194-1204
    • Cuzner, M.L.1    Gveric, D.2    Strand, C.3
  • 61
    • 0030483220 scopus 로고    scopus 로고
    • Interferon-β1b inhibits gelatinase secretion and in vitro migration of human T cells: A possible mechanism for treatment efficacy in multiple sclerosis
    • Leppert D, Waubant E, Buerk MR, et al. Interferon-β1b inhibits gelatinase secretion and in vitro migration of human T cells: a possible mechanism for treatment efficacy in multiple sclerosis. Ann Neurol 1996;40:846-853
    • (1996) Ann Neurol , vol.40 , pp. 846-853
    • Leppert, D.1    Waubant, E.2    Buerk, M.R.3
  • 62
    • 0030498666 scopus 로고    scopus 로고
    • Interferon-1βb decreases the migration of T lymphocytes in vitro: Effects on matrix metalloproteinase-9
    • Stueve O, Dooley NP, Uhm JH, et al. Interferon-1βb decreases the migration of T lymphocytes in vitro: effects on matrix metalloproteinase-9. Ann Neurol 1996;40:853-863
    • (1996) Ann Neurol , vol.40 , pp. 853-863
    • Stueve, O.1    Dooley, N.P.2    Uhm, J.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.