The X philes: Structure-specific endonucleases that resolve Holliday junctions

Molecular Microbiology

Volumn 39, Issue 4, 2001, Pages 823-834

  Sharples, G J ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA; ENDONUCLEASE; RESOLVASE; SINGLE STRANDED DNA; WATER;

ARCHAEBACTERIUM; BACTERIOPHAGE; BACTERIUM; CELL DIVISION; DNA BINDING; DNA CLEAVAGE; DNA REPAIR; DNA REPLICATION; DNA STRAND BREAKAGE; ENZYME STRUCTURE; GENETIC RECOMBINATION; HOLLIDAY JUNCTION; HYDROLYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; POXVIRUS; PRIORITY JOURNAL; SHORT SURVEY; YEAST;

ARCHAEA; BACTERIAL PROTEINS; BACTERIOPHAGES; CATALYSIS; DNA; ENDODEOXYRIBONUCLEASES; ENDONUCLEASES; ESCHERICHIA COLI PROTEINS; NUCLEIC ACID CONFORMATION; RECOMBINASES; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSPOSASES;

ARCHAEA; BACTERIA (MICROORGANISMS); POXVIRIDAE; UNIDENTIFIED BACTERIOPHAGE;

EID: 0035117855     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2001.02284.x     Document Type: Short Survey

References (74)

1. Holliday junction resolvases and related nucleases: Identification of new families, phyletic distribution and evolutionary trajectories
2. Atomic structure of the RuvC resolvase: A Holliday junction-specific endonuclease from E. coli
3. Crystal structure of the Holliday junction DNA in complex with a single RuvA tetramer
4. Structural analysis of the RuvC-Holliday junction complex reveals an unfolded junction
5. Lactococcus lactis phage operon coding for an endonuclease homologous to RuvC
6. Identification of three aspartic acid residues essential for catalysis by the RusA Holliday junction resolvase
7. Analysis of conserved basic residues associated with DNA binding (Arg69) and catalysis (Lys76) by the RusA Holliday junction resolvase
8. Evolutionary comparisons of RecA-like proteins across all major kingdoms of living organisms
9. Sequence-specificity and biochemical characterization of the RusA Holliday junction resolvase of Escherichia coli
10. Recognition and manipulation of branched DNA by the RusA Holliday junction resolvase of Escherichia coli
11. Resolution of Holliday junctions in vitro requires the Escherichia coli ruvC gene product
12. Formation of RuvABC-Holliday junction complexes in vitro
13. Extensive central disruption of a four-way junction on binding CCE1 resolving enzyme
14. The site-specific cleavage of synthetic Holliday junction analogs and related branched DNA structures by bacteriophage T7 endonuclease I
15. Cruciform extrusion in plasmids bearing the replicative intermediate configuration of a poxvirus telomere
16. - phenotype by expression of a bacterial Holliday junction resolvase
17. The structure of the Holliday junction, and its resolution
18. The structure of DNA junctions and their interactions with enzymes
19. Binding of the junction-resolving enzyme bacteriophage T7 endonuclease I to DNA: Separation of binding and catalysis by mutation
20. Nucleic acid structure and recognition
21. Formation and resolution of recombination intermediates by E. coli RecA and RuvC proteins
22. Cleavage of Holliday junctions by the Escherichia coli RuvABC complex
23. The Holliday junction in an inverted repeat DNA sequence: Sequence effects on the structure of four-way junctions
24. Bacterial-type DNA Holliday junction resolvases in eukaryotic viruses
25. Near-simultaneous DNA cleavage by the subunits of the junction-resolving enzyme T4 endonuclease VII
26. Structural recognition and distortion by the DNA junction-resolving enzyme RusA
27. Association of Holliday-structure resolving endonuclease VII with gp20 from the packaging machine of phage T4
28. Structure of Cre recombinase complexed with DNA in a site-specific recombination synapse
29. Crystal structure of the Holliday junction-resolving enzyme T7 endonuclease I at 2.1Å resolution
30. Crystal structure of E. coli RuvA with bound DNA Holliday junction at 6Å resolution
31. Efficient RecABC-dependent, homologous recombination between coliphage lambda and plasmids requires a phage ninR region gene
32. Resolution of recombination intermediates by a mammalian activity functionally analogous to Escherichia coli RuvC resolvase
33. E. coli RuvC protein is an endonuclease that resolves the Holliday structure, an intermediate of homologous recombination
34. Branched DNA resolving enzymes (X-solvases)
35. Function of gene 49 of bacteriophage T4. II. Analysis of intracellular development and the structure of very fast sedimenting DNA
36. Identification and characterization of yeast mutants and the gene for a cruciform cutting endonuclease
37. A Holliday junction resolvase from Pyrococcus furiosus: Functional similarity to Escherichia coli RuvC provides evidence for conserved mechanism of homologous recombination in Bacteria, Eukarya, and Archaea
38. Mutational analysis of the Pyrococcus furiosus Holliday junction resolvase Hjc revealed functionally important residues for dimer formation, junction DNA binding and cleavage activities
39. Both RadA and RadB are involved in homologous recombination in Pyrococcus furiosus
40. Two Holliday junction resolving enzymes in Sulfolobus solfataricus
41. An Archaeal Holliday junction resolving enzyme from Sulfolobus solfataricus exhibits unique properties
42. A conserved nuclease domain in the archaeal Holliday junction resolving enzyme Hjc
43. Resolving the relationships of resolving enzymes
44. A role for recombination junctions in the segregation of mitochondrial DNA in yeast
45. Modulation of RNA polymerase by (p)ppGpp reveals a RecG-dependent mechanism for replication fork progression
46. Holliday junction resolvases encoded by homologous rusA genes in Escherichia coli K-12 and phage 82
47. Bacteriophages in the evolution of pathogen-host interactions
48. Resolution of Holliday junctions by RuvABC prevents dimer formation in rep mutants and UV-irradiated cells
49. Recombination and recombination-dependent DNA replication in bacteriophage T4
50. Archaeal genomics: An overview
51. Catalytic and binding mutants of the junction-resolving enzyme endonuclease I of bacteriophage T7: Role of acidic residues
52. Cleavage specificity of bacteriophage T4 endonuclease VII and bacteriophage T7 endonuclease I on synthetic branch migratable Holliday junctions
53. T4 endonuclease VII selects and alters the structure of the four-way DNA junction; binding of a resolution-defective mutant enzyme
54. X-ray structure of T4 endonuclease VII: A DNA junction resolvase with a novel fold and unusual domain-swapped dimer architecture
55. Identification of four acidic amino acids that constitute the catalytic center of the RuvC Holliday junction resolvase
56. Dissection of the sequence specificity of the Holliday junction endonuclease CCE1
57. RuvAB acts at arrested replication forks
58. RadA protein is an archaeal RecA protein homolog that catalyzes DNA strand exchange
59. Resolution of Holliday junctions by eukaryotic DNA topoisomerase I
60. Genetic recombination in E. coli RuvC protein cleaves Holliday junctions at resolution hotspots in vitro
61. λ Rap protein is a structure-specific endonuclease involved in phage recombination
62. Holliday junction processing in bacteria: Insights from the evolutionary conservation of RuvABC, RecG, and RusA
63. DNA structure specificity of Rap endonuclease
64. Analysis of substrate specificity of the RuvC Holliday junction resolvase with synthetic Holliday junctions
65. In vitro resolution of poxvirus replicative intermediates into linear minichromosomes with hairpin termini by a virally induced Holliday junction endonuclease
66. Site directed mutagenesis of the yeast resolving enzyme Cce1 reveals catalytic residues and relationship with the intron splicing factor Mrs1
67. Enzymes and molecular mechanisms of genetic recombination
68. Cleavage of cruciform DNA structures by an activity from Saccharomyces cerevisiae
69. A new Holliday junction resolving enzyme from Schizosaccharomyces pombe that is homologous to CCE1 from Saccharomyces cerevisiae
70. Interactions between RuvA and RuvC at Holliday junctions: Inhibition of junction cleavage and formation of a RuvA-RuvC-DNA complex
71. The resolving enzyme CCE1 of yeast opens the structure of the four-way DNA junction
72. Recognition and manipulation of branched DNA structure by junction-resolving enzymes
73. Recombining the structures of HIV integrase, RuvC and RNase H
74. Effect of DNA topology on Holliday junction resolution by Escherichia coli RuvC and bacteriophage T7 endonuclease I