Frontal 5-HT(2A) receptors studied in depressive patients during chronic treatment by selective serotonin reuptake inhibitors

Psychopharmacology

Volumn 133, Issue 1, 1997, Pages 99-101

  Massou, J M ^a,b   Trichard, C ^a   Attar Levy, D ^c   Feline, A ^d   Corruble, E ^e   Beaufils, B ^b   Martinot, J L ^a,d  

^a SERVICE HOSPITALIER FRÉDÉRIC JOLIOT   (France)

^b Paris Descartes University   (France)

^c Service Hospitalo   (France)

^d BICÊTRE HOSPITAL   (France)

^e HÔPITAL PAUL BROUSSE   (France)

Author keywords

5 HT(2A) receptor; Depression; Positron emission tomography; Serotonin selective reuptake inhibitors

Indexed keywords

FLUOXETINE; FLUVOXAMINE; SEROTONIN 2A RECEPTOR; ANTIDEPRESSANT AGENT; DIAGNOSTIC AGENT; FLUORINE; PYRIMIDINONE DERIVATIVE; SEROTONIN RECEPTOR; SEROTONIN UPTAKE INHIBITOR; SETOPERONE;

ADULT; ARTICLE; CLINICAL ARTICLE; DEPRESSION; DRUG MECHANISM; DRUG RECEPTOR BINDING; FEMALE; HUMAN; MALE; ORAL DRUG ADMINISTRATION; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RADIOACTIVITY; RECEPTOR UPREGULATION; COMPARATIVE STUDY; COMPUTER ASSISTED EMISSION TOMOGRAPHY; FRONTAL LOBE; METABOLISM; MIDDLE AGED; SCINTISCANNING;

ADULT; ANTIDEPRESSIVE AGENTS; DEPRESSIVE DISORDER; FEMALE; FLUORINE RADIOISOTOPES; FRONTAL LOBE; HUMANS; MALE; MIDDLE AGED; PYRIMIDINONES; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTORS, SEROTONIN; SEROTONIN UPTAKE INHIBITORS; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0030611828     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002130050377     Document Type: Article

References (17)

1. Beasley CM, Masica DN, Potvin JH (1992) Fluoxetine: a review of receptor and functional effects and their clinical implications. Psychopharmacology 107:1-10
2. 18F-labeled setoperone. J Neurochem 54:1744-1754
3. 2 receptor in Alzheimer's disease. Brain 116:497-510
4. 2 receptors in depression. Psychiatr Res Neuroimag 45:227-237
5. Green AR, Johnson P, Mountford JA, Nimgaonkar VL (1985) Some anticonvulsant drugs alter monoamine-mediated behaviour in mice in ways similar to electroconvulsive shock: implications for antidepressant therapy. Br J Pharmacol 84:337-346
6. 2 receptors of the human brain postmortem. Brain Res 519:223-227
7. Hyttel J, Overo KF, Arnt J (1984) Biochemical effects and drug levels in rats after long-term treatment with the specific 5-HT-uptake inhibitor, citalopram. Psychopharmacology 83:20-27
8. 2 receptors in the rat brain. J Psychiatr Neurosci 19:63-67
9. Le Poul E, Lima L, Laporte AM, Even C, Doucet E, Fattaccini CM, Laaris N, Hamon M, Lanfumey L (1995) Récepteurs centraux de la sérotonine et traitements chroniques avec un inhibiteur spécifique de la recapture de la sérotonine chez le rat: effets comparés de la fluoxétine et de la paroxétine. Encéphale 21:123-132
10. 2 receptors in rat brain following chronic receptor blockade. J Recept Res 7:223-239
11. McKeith IG, Marshall EF, Ferrier IN, Armstrong MM, Kennedy WN, Perry RH, Perry EK, Eccleston D (1987) 5-HT receptor binding in post-mortem brain from patients with affective disorder. J Affect Disord 13:67-74
12. Nelson DR, Thomas DR, Johnson AM (1989) Pharmacological effects of paroxetine after repeated administration to animals. Acta Psychiatr Scand 80 [suppl 350]:21-23
13. Peroutka SJ, Snyder SH (1980) Long-term antidepressant treatment decreases spiroperidol-labeled serotonin receptor binding. Science 210:88-90
14. Schoups AA, De Potter WP (1988) Species dependence of adaptations at the pre- and postsynaptic serotonergic receptors following long-term antidepressant drug treatment. Biochem Pharmacol 37:4451-4460
15. 2 binding sites in rat frontal cortex. In: Fahn S, Marsden D, Van Woert M (eds) Myoclonus (advances in neurology, vol 43). Raven Press, New York, pp 645-651
16. Wamsley JK, Byerley WF, McCabe RT, Mc Connel EJ, Dawson TM, Grosser BI (1987) Receptor alterations associated with serotonergic agents: an autoradiocraphic analysis. J Clin Psychiatry 48(suppl):19-25
17. 2 receptor changes in major depression. Biol Psychiatry 27:489-496