SCOPUS 정보 검색 플랫폼

Toxicological Sciences

Volumn 60, Issue 1, 2001, Pages 56-62

Androgen receptor antagonism by the organophosphate insecticide fenitrothion

(6) Tamura, Hiroto a,b Maness, Susan C b Reischmann, Kim b Dorman, David C b Earl Gray, L c Gaido, Kevin W b

a MEIJO UNIVERSITY (Japan)

b CIIT CENTERS FOR HEALTH RESEARCH (United States)

c U S ENVIRONMENTAL PROTECTION AGENCY (United States)

Author keywords

Androgen receptor; Antiandrogen; Endocrine active chemical; HepG2 cells; Hershberger assay; Organophosphate pesticide; Transcriptional activation

Indexed keywords

1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHYLENE; ACETYLCHOLINESTERASE; ANDROGEN RECEPTOR; ANDROSTANOLONE; ANTIANDROGEN; BIOLOGICAL MARKER; CORN OIL; FENITROTHION; FLUTAMIDE; LINURON; LUCIFERASE; ORGANOPHOSPHATE INSECTICIDE; PENTOBARBITAL; TESTOSTERONE PROPIONATE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD; BRAIN; CHEMICAL STRUCTURE; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEMOGRAPHY; DISSOCIATION CONSTANT; DRUG POTENCY; DRUG STRUCTURE; ENZYME ACTIVITY; EXPOSURE; FEEDING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INTOXICATION; LEVATOR ANI MUSCLE; MALE; MOTOR ACTIVITY; NONHUMAN; RAT; RAT STRAIN; RECEPTOR INTRINSIC ACTIVITY; REGRESSION ANALYSIS; REPORTER GENE; RURAL AREA; SEMINAL VESICLE; WEIGHT;

ACETYLCHOLINESTERASE; ANIMALS; BODY WEIGHT; CARCINOMA, HEPATOCELLULAR; CHOLINESTERASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; FENITROTHION; FLUTAMIDE; GENITALIA, MALE; HUMANS; INSECTICIDES; LIVER; MALE; MOTOR ACTIVITY; MUSCLE, SKELETAL; ORGAN SIZE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ANDROGEN; TRANSFECTION; TUMOR CELLS, CULTURED;

ANIMALIA; ZEA MAYS;

EID: 0035090770 PISSN: 10966080 EISSN: None Source Type: Journal
DOI: 10.1093/toxsci/60.1.56 Document Type: Article

Times cited : (145)

References (41)

1
- 0009644628
- Some quantitative uses of drug antagonists
- (1959) Br. J. Pharmacol. , vol.14 , pp. 48-58
- Arunlakshana, O.¹ Schild, H.O.²

2
- 0033967188
- The peripubertal male rat assay as an alternative to the Hershberger castrated-male-rat assay for the detection of anti-androgens, oestrogens and metabolic modulators
- (2000) J. Appl. Toxicol. , vol.20 , pp. 35-47
- Ashby, J.¹ Lefevre, P.A.²

3
- 0032216367
- Comparative organophosphate-induced effects observed in adult and neonatal Sprague-Dawley rats during the conduct of multigeneration toxicity studies
- (1998) Reprod. Toxicol. , vol.12 , pp. 619-645
- Astroff, A.B.¹ Freshwater, K.J.² Eigenberg, D.A.³

4
- 0030907094
- Transcriptional activation of the human estrogen receptor by DDT isomers and metabolites in yeast and MCF-7 cells
- (1997) Biochem. Pharmacol. , vol.53 , pp. 1161-1172
- Chen, C.W.¹ Hurd, C.² Vorojeikina, D.P.³ Arnold, S.F.⁴ Notides, A.C.⁵

5
- 0018058706
- Postnatal endocrine dysfunction resulting from prenatal exposure to carbofuran, diazinon or chlordane
- (1978) J. Environ. Pathol. Toxicol. , vol.2 , pp. 357-369
- Cranmer, J.S.¹ Avery, D.L.² Grady, R.R.³ Kitay, J.I.⁴

6
- 0005685137
- Standard methods adopted by official organizations: Cancer Chemotherapy National Service Center Program
- (R.L. Dorfman, Ed.), U.S. Public Health Service, New York.
- (1962) Methods in Hormone Research , pp. 707-730
- Dorfman, R.L.¹

7
- 0033961696
- Fertility and development neurotoxicity effects of inhaled hydrogen sulfide in Sprague-Dawley rats
- (2000) Neurotoxicol. Teratol. , vol.22 , pp. 71-84
- Dorman, D.C.¹ Brenneman, K.A.² Struve, M.F.³ Miller, K.L.⁴ James, R.A.⁵ Marshall, M.W.⁶ Foster, P.⁷

8
- 0032791061
- Exposures of children to organophosphate pesticides and their potential adverse health effects
- (1999) Environ. Health Perspect. , vol.107 , Issue.SUPPL. 3 , pp. 409-419
- Eskenazi, B.¹ Bradman, A.² Castorina, R.³

9
- 0031105822
- Evaluation of chemicals with endocrine-modulating activity in a yeast-based steroid hormone receptor gene transcription assay
- (1997) Toxicol. Appl. Pharmacol. , vol.143 , pp. 205-212
- Gaido, K.W.¹ Leonard, L.S.² Lovell, S.³ Gould, J.C.⁴ Babai, D.⁵ Portier, C.J.⁶ McDonnell, D.P.⁷

10
- 0033304499
- Differential interaction of the methoxychlor metabolite 2,2′-bis-(p-hydroxyphenyl)-1,1,1-trichloroethane with estrogen receptors alpha and beta
- (1999) Endocrinology , vol.140 , pp. 5746-5753
- Gaido, K.W.¹ Leonard, L.S.² Maness, S.C.³ Hall, J.M.⁴ McDonnell, D.P.⁵ Saville, B.⁶ Safe, S.⁷

11
- 0343962125
- Environmental antiandrogens: Low doses of the fungicide vinclozolin alter sexual differentiation of the male rat
- (1999) Toxicol. Ind. Health , vol.15 , pp. 48-64
- Gray L.E., Jr.¹ Ostby, J.² Monosson, E.³ Kelce, W.R.⁴

12
- 0343090362
- Administration of potentially antiandrogenic pesticides (procymidone, linuron, iprodione, chlozolinate, p,p′-DDE, and ketoconazole) and toxic substances (dibutyl- and diethylhexyl phthalate, PCB 169, and ethane during sexual differentiation produces diverse profiles of reproductive malformations in the male rat
- (1999) Toxicol. Ind. Health , vol.15 , pp. 94-118
- Gray L.E., Jr.¹ Wolf, C.² Lambright, C.³ Mann, P.⁴ Price, M.⁵ Cooper, R.L.⁶ Ostby, J.⁷

13
- 84964130498
- Myotrophic activity of 19-nortestosterone and other steroids determined by modified levator ani muscle method
- (1953) Proc. Soc. Exp. Biol. Med. , vol.83 , pp. 175-180
- Hershberger, L.¹ Shipley, E.² Meyer, R.³

14
- 0027289630
- The affinity of procymidone to androgen receptor in rats and mice
- (1993) Toxicol. Sci. , vol.18 , pp. 83-93
- Hosokawa, S.¹ Murakami, M.² Ineyama, M.³ Yamada, T.⁴ Yoshitake, A.⁵ Yamada, H.⁶ Miyamoto, J.⁷

15
- 0029047149
- Persistent DDT metabolite p,p′-DDE is a potent androgen receptor antagonist
- (1995) Nature , vol.375 , pp. 581-585
- Kelce, W.R.¹ Stone, C.R.² Laws, S.C.³ Gray, L.E.⁴ Kemppainen, J.A.⁵ Wilson, E.M.⁶

16
- 0002769868
- Competitive antagonism
- Pharmacological Analysis of Drug-Receptor Interaction, Raven Press, New York.
- (1993) , pp. 278-322
- Kenakin, T.¹

17
- 0027222826
- Bisphenol-A: An estrogenic substance is released from polycarbonate flasks during autoclaving
- (1993) Endocrinology , vol.132 , pp. 2279-2286
- Krishnan, A.V.¹ Stathis, P.² Permuth, S.F.³ Tokes, L.⁴ Feldman, D.⁵

18
- 85033038203
- Immunotoxicological insignificance of fenitrothion in mice and rats
- (1996) Fundam. Appl. Toxicol. , vol.33 , pp. 246-253
- Kunimatsu, T.¹ Kamita, Y.² Isobe, N.³ Kawasaki, H.⁴

19
- 0033931562
- Cellular and molecular mechanisms of action of linuron: An antiandrogenic herbicide that produces reproductive malformations in male rats
- (2000) Toxicol. Sci. , vol.56 , pp. 389-399
- Lambright, C.¹ Ostby, J.² Bobseine, K.³ Wilson, V.⁴ Hotchkiss, A.K.⁵ Mann, P.C.⁶ Gray L.E., Jr.⁷

20
- 0032802028
- Pesticides and inner-city children: Exposures, risks, and prevention
- (1999) Environ. Health Perspect. , vol.107 , Issue.SUPPL. 3 , pp. 431-437
- Landrigan, P.J.¹ Claudio, L.² Markowitz, S.B.³ Berkowitz, G.S.⁴ Brenner, B.L.⁵ Romero, H.⁶ Wetmur, J.G.⁷ Matte, T.D.⁸ Gore, A.C.⁹ Godbold, J.H.¹⁰ Wolff, M.S.¹¹

21
- 0031904834
- 1997 Annual report of the American association of poison control centers toxic exposure surveillance system
- (1998) Am. J. Emerg. Med. , vol.16 , pp. 443-497
- Litovitz, T.L.¹ Klein-Schwartz, W.² Dyer, K.S.³ Shannon, M.⁴ Lee, S.⁵ Powers, M.⁶

22
- 0031752451
- Inhibition of androgen receptor-dependent transcriptional activity by DDT isomers and methoxychlor in HepG2 human hepatoma cells
- (1998) Toxicol. Appl. Pharmacol. , vol.151 , pp. 135-142
- Maness, S.C.¹ McDonnell, D.P.² Gaido, K.W.³

23
- 0034283411
- Effects of in utero exposure to linuron on androgen-dependent reproductive development in the male Crl:CD(SD)BR rat
- (2000) Toxicol. Appl. Pharmacol. , vol.167 , pp. 87-99
- McIntyre, B.S.¹ Barlow, N.J.² Wallace, D.G.³ Maness, S.C.⁴ Gaido, K.W.⁵ Foster, P.M.⁶

24
- 0033360298
- Peripubertal exposure to the antiandrogenic fungicide, vinclozolin, delays puberty, inhibits the development of androgen-dependent tissues, and alters androgen receptor function in the male rat
- (1999) Toxicol. Ind. Health , vol.15 , pp. 65-79
- Monosson, E.¹ Kelce, W.R.² Lambright, C.³ Ostby, J.⁴ Gray L.E., Jr.⁵

25
- 0005774018
- National Research Council Pesticides in the Diets of Infants and Children. National Academy Press, Washington.
- (1993)

26
- 0005702259
- National Research Council Hormonally Active Agents in the Environment. National Academy Press, Washington.
- (1999)

27
- 0033654537
- Blood cholinesterases as human biomarkers of organophosphorous pesticide exposure
- (2000) Rev. Environ. Contam. Toxicol. , vol.163 , pp. 29-111
- Nigg, H.N.¹ Knaak, J.B.²

28
- 0032822886
- Detection of the environmental antiandrogen p,p′-DDE in CD and Long-Evans rats using a Tier I screening battery and a Hershberger assay
- (1999) Toxicol. Sci. , vol.51 , pp. 44-53
- O'Connor, J.C.¹ Frame, S.R.² Davis, L.G.³ Cook, J.C.⁴

29
- 0034021332
- Self reported symptoms and inhibition of acetylcholinesterase activity among Kenyan agricultural workers
- (2000) Occup. Environ. Med. , vol.57 , pp. 195-200
- Ohayo-Mitoko, G.J.¹ Kromhout, H.² Simwa, J.M.³ Boleij, J.S.⁴ Heederik, D.⁵

30
- 0033363929
- The fungicide procymidone alters sexual differentiation in the male rat by acting as an androgen-receptor antagonist in vivo and in vitro
- (1999) Toxicol. Ind. Health , vol.15 , pp. 80-93
- Ostby, J.¹ Kelce, W.R.² Lambright, C.³ Wolf, C.J.⁴ Mann, P.⁵ Gray L.E., Jr.⁶

31
- 0033369584
- Organophosphorous pesticides: Do they all have the same mechanism of toxicity?
- (1999) J. Toxicol. Environ. Health B Crit. Rev. , vol.2 , pp. 161-181
- Pope, C.N.¹

32
- 0020354339
- Oviposition and the plasma concentrations of LH, progesterone, and corticosterone in bobwhite quail (Colinus virginianus) fed parathion
- (1982) J. Reprod. Fertil. , vol.66 , pp. 147-155
- Rattner, B.A.¹ Sileo, L.² Scanes, C.G.³

33
- 0021854392
- Carcinogenicity and toxicity of malathion and malaoxon
- (1985) Environ. Res. , vol.37 , pp. 119-153
- Reuber, M.D.¹

34
- 0034007911
- Organophosphates and their impact on the global environment
- (2000) Neurotoxicology , vol.21 , pp. 223-227
- Satoh, T.¹ Hosokawa, M.²

35
- 0017713072
- The effect of chronic ingestion of selected pesticides upon rat ventral prostate homeostasis
- (1977) Toxicol. Appl. Pharmacol. , vol.40 , pp. 115-130
- Shain, S.A.¹ Shaeffer, J.C.² Boesel, R.W.³

36
- 0026042049
- p-Nonylphenol: An estrogenic xenobiotic released from "modified" polystyrene
- (1991) Environ. Health. Perspect. , vol.92 , pp. 167-173
- Soto, A.M.¹ Honorato, J.² Wray, J.W.³ Sonnenschein, C.⁴

37
- 0028149404
- Mammalian toxicology of organophosphorous pesticides
- (1994) J. Toxicol. Environ. Health , vol.43 , pp. 271-289
- Sultatos, L.G.¹

38
- 0000154866
- Endocrine disrupter screening program; Proposed statement of policy
- U.S. EPA
- (1998) Fed. Regist. , vol.63 , pp. 71541-71568

39
- 0028233813
- Environmentally persistent alkylphenolic compounds are estrogenic
- (1994) Endocrinology , vol.135 , pp. 175-182
- White, R.¹ Jobling, S.² Hoare, S.A.³ Sumpter, J.P.⁴ Parker, M.G.⁵

40
- 0029123855
- Androgen receptor antagonist versus agonist activities of the fungicide vinclozolin relative to hydroxyflutamide
- (1995) J. Biol. Chem. , vol.270 , pp. 19998-20003
- Wong, C.I.¹ Kelce, W.R.² Sar, M.³ Wilson, E.M.⁴

41
- 0033572852
- In utero exposure to antiandrogens alters the responsiveness of the prostate to p,p′-DDE in adult rats and may induce prostatic inflammation
- (1999) Toxicol. Appl. Pharmacol. , vol.161 , pp. 258-266
- You, L.¹ Brenneman, K.A.² Heck, H.³

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.