The peripubertal male rat assay as an alternative to the Hershberger castrated male rat assay for the detection of anti-androgens, oestrogens and metabolic modulators

Journal of Applied Toxicology

Volumn 20, Issue 1, 2000, Pages 35-47

  Ashby, J ^a   Lefevre, P A ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

Androgens; Endocrine disruption; Immature rats; Oestrogens; Sexual development

Indexed keywords

1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHYLENE; 4,4' ISOPROPYLIDENEDIPHENOL; ANASTROZOLE; ANTIANDROGEN; CYPROTERONE ACETATE; DIETHYLSTILBESTROL; ESTROGEN; FENITROTHION; FINASTERIDE; FLUTAMIDE; KETOCONAZOLE; METHOXYCHLOR; PHTHALIC ACID DERIVATIVE; PHTHALIC ACID DIBUTYL ESTER; VINCLOZOLIN;

ADOLESCENT; ANIMAL EXPERIMENT; ARTICLE; BIOASSAY; BODY WEIGHT; ENDOCRINE SYSTEM; EPIDIDYMIS; KIDNEY; LIVER WEIGHT; MALE; METABOLIC DISORDER; NONHUMAN; PREPUCE; PRIORITY JOURNAL; PROSTATE; RAT; SEMINAL VESICLE; TESTIS WEIGHT;

ANDROGEN ANTAGONISTS; ANIMALS; BIOLOGICAL ASSAY; BODY WEIGHT; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTROGENS, NON-STEROIDAL; FENITROTHION; FINASTERIDE; GENITALIA, MALE; HUMANS; KETOCONAZOLE; MALE; NITRILES; ORCHIECTOMY; ORGAN SIZE; PUBERTY; RATS; SEXUAL MATURATION; TRIAZOLES;

ANIMALIA;

EID: 0033967188     PISSN: 0260437X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1263(200001/02)20:1<35::AID-JAT633>3.0.CO;2-8     Document Type: Article

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