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1
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0026651273
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Human cytochromes P450: Problems and prospects
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F. J. Gonzalez: Human cytochromes P450: problems and prospects. Trends Pharmacol Sci. 13, 346-352 (1992).
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Gonzalez, F.J.1
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cDNA-directed expression of human cytochrome P450 CYP3A4 using baculovirus
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J. T. M. Buters, K. R. Korzekwa, K. L. Kunze, Y. Omata, J. P. Hardwick and F. J. Gonzalez: cDNA-directed expression of human cytochrome P450 CYP3A4 using baculovirus. Drug Metab. Dispos. 22, 688-692 (1994).
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Drug Metab. Dispos.
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4
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0029010216
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cDNA-directed expression of human cytochrome P450 CYP1A1 using baculovirus
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J. T. M. Buters, M. Shou, J. P. Hardwick, K. R. Korzekwa, and F. J. Gonzalez: cDNA-directed expression of human cytochrome P450 CYP1A1 using baculovirus. Drug Metab. Dispos. 23, 696-701 (1995).
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5
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Cytochrome P450 2A1, 2E1, and 2C9 cDNA-expression by insect cells and partial purification using hydrophobic chromatography
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J. Grogan, M. Shou, E. A. Andrusiak, S. Tamuro, J. T. M. Buters, F. J. Gonzalez, and K. R. Korzekwa: Cytochrome P450 2A1, 2E1, and 2C9 cDNA-expression by insect cells and partial purification using hydrophobic chromatography. Biochem. Pharmacol. 50, 1509-1515 (1995).
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0029012009
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CYP3A4 expressed by insect cells infected with a recombinant baculovirus containing both CYP3A4 and human NADPH-cytochrome P450 reductase is catalytically similar to human liver microsomal CYP3A4
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C. A. Lee, S. H. Kadwell, T. A. Kost, and C. J. Serabjit-Singh: CYP3A4 expressed by insect cells infected with a recombinant baculovirus containing both CYP3A4 and human NADPH-cytochrome P450 reductase is catalytically similar to human liver microsomal CYP3A4. Arch. Biochem. Biophys. 319, 157-167 (1995).
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Baculovirus-mediated expression and functional characterization of human NADPH-P450 oxidoreductase
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S. Tamura, K. R. Korzekwa, S. Kimura, H. V. Gelboin, and F. J. Gonzalez: Baculovirus-mediated expression and functional characterization of human NADPH-P450 oxidoreductase. Arch. Biochem. Biophys. 293, 219-223 (1992).
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A baculovirus dual expression vector derived from the Autographa californica nuclear polyhidrosis virus polyhedrin and p10 promoters: Co-expression of two influenza virus genes in insect cells
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U. Weyer and R. D. Possee: A baculovirus dual expression vector derived from the Autographa californica nuclear polyhidrosis virus polyhedrin and p10 promoters: co-expression of two influenza virus genes in insect cells. J. Gen. Virol. 72, 2967-2974 (1991).
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9
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The CYP2A gene subfamily: Species differences, regulation, catalytic activities and role in chemical carcinogenesis
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P. Fernandez-Salguero and F. J. Gonzalez: The CYP2A gene subfamily: species differences, regulation, catalytic activities and role in chemical carcinogenesis. Pharmacogenetics 5, S123-128 (1995).
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Pharmacogenetics
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Individual expression of carcinogen-metabolizing enzymes: Cytochrome P4502A
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C. L. Crespi, B. W. Penmen, J. A. E. Leakey, M. P. Arlotto, A. Stark, A. Parkinson, T. Turner, D. T. Steimel, K. Rudo, R. L. Davies, and R. Langenbach: Human cytochrome P450IIA3: cDNA sequence, role of the enzyme in the metabolic activation of promutagens, comparison to nitrosamine activation by human cytochrome P450IIE1. Carcinogenesis 8, 1293-1300 (1990).
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A tobacco smoke-derived nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, is activated by multiple human cytochrome P450s including the polymorphic human cytochrome P4502D6
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C. L. Crespi, B. W. Penman, H. V. Gelboin, and F. J. Gonzalez: A tobacco smoke-derived nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, is activated by multiple human cytochrome P450s including the polymorphic human cytochrome P4502D6. Carcinogenesis 12, 1197-1201 (1991).
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Rat testosterone 7α-hydroxylase
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K. Nagata, T. Matsunaga, J. Gillette, H. V. Gelboin, and F. J. Gonzalez: Rat testosterone 7α-hydroxylase. J. Biol. Chem. 262, 2787-2793 (1987).
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Human NADPH-P450 oxidoreductase: Complementary DNA cloning, sequence and vaccinia virus-mediated expression and localization of the CYPOR gene to chromosome 7
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S. Yamano, T. Aoyama, O. W. McBride, J. P. Hardwick, H. V. Gelboin, and F. J. Gonzalez: Human NADPH-P450 oxidoreductase: complementary DNA cloning, sequence and vaccinia virus-mediated expression and localization of the CYPOR gene to chromosome 7. Mol. Pharmacol. 35, 83-88 (1989).
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An improved assay of 7-ethoxycoumarin ο-deethylase activity: Induction of hepatic enzyme activity in C57BL/6J and DBA/2J mice by phenobarbital, 3-methylcholanthrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin
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W. F. Greenlee and A. Poland: An improved assay of 7-ethoxycoumarin ο-deethylase activity: induction of hepatic enzyme activity in C57BL/6J and DBA/2J mice by phenobarbital, 3-methylcholanthrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin. J. Pharmacol. Exp. Ther. 205, 596-605 (1978).
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Novel exogenous heme-dependent expression of mammalian cytochrome P450 using baculovirus
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A. Asseffa, S. J. Smith, K. Nagata, J. Gillette, H. V. Gelboin, and F. J. Gonzalez: Novel exogenous heme-dependent expression of mammalian cytochrome P450 using baculovirus. Arch. Biochem. Biophys. 274, 481-490 (1989).
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Expression and characterization of a rabbit liver cytochrome P450 belonging to P450IIB subfamily with the aid of the baculovirus expression vector system
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D. Ohta, Y. Matsu-ura, and R. Sato: Expression and characterization of a rabbit liver cytochrome P450 belonging to P450IIB subfamily with the aid of the baculovirus expression vector system. Biochem. Biophys. Res. Comm. 175, 394-399 (1991).
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The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsome
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NADPH-P-450 reductase: Structural and functional comparisons of the eukaryotic and prokaryotic isoforms
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Quantitative analyses of electrostatic interactions between NADPH-cytochrome P450 reductase and cytochrome P450 enzymes
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