High frequency of CYP1A1 mutations in a Turkish population

Archives of Toxicology

Volumn 72, Issue 4, 1998, Pages 215-218

  Aynacioglu, A Sükrü ^a,b   Cascorbi, Ingolf ^a   Mrozikiewicz, Przemyslaw M ^a   Roots, Ivar ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b GAZIANTEP UNIVERSITY   (Turkey)

Author keywords

CYP1A1; Cytochrome P4501A1; Molecular epidemiology; Peptide nucleic acids; PNA; Turkish population

Indexed keywords

CYTOCHROME P450 ISOENZYME;

ADOLESCENT; ADULT; AGED; ALLELE; ARTICLE; FEMALE; GENE MUTATION; GENE SEQUENCE; HUMAN; HUMAN CELL; LEUKOCYTE; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; POPULATION GENETICS; PRIORITY JOURNAL; PROTEIN POLYMORPHISM; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; TURKEY (REPUBLIC);

EID: 0031958666     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002040050491     Document Type: Article

References (27)

1. Aynacioglu AS, Cascorbi I, Mrozikiewicz PM, Roots I (1997) Arylamine N-acetyltransferase (NAT2) genotypes in a Turkish population. Pharmacogenetics 7: 327-331
2. Basci NE, Brøsen K, Bozkurt A, Isimer A, Sayal A, Kayaalp SO (1994) S-Mephenytoin, sparteine and debrisoquine oxidation: genetic polymorphisms in a Turkish population. Br J Clin Pharmacol 38: 463-465
3. Cascorbi I, Brockmöller J, Roots I (1996) A C4887A polymorphism in exon 7 of human CYP1A1: population frequency, mutation linkages, and impact on lung cancer susceptibility. Cancer Res 56: 4965-4969
4. Crofts F, Cosma GN, Currie D, Taioli E, Toniolo P, Garte SJ (1993) A novel CYP1A1 gene polymorphism in African-Americans. Carcinogenesis 14: 29-31
5. Crofts F, Taioli E, Trachman J, Cosma GN, Currie D, Toniolo P, Garte SJ (1994) Functional significance of different CYP1A1 genotypes. Carcinogenesis 15: 2691-2693
6. Drakoulis N, Cascorbi I, Brockmöller J, Gross CR, Roots I (1994) Polymorphisms in the human CYP1A1 gene as susceptibility factors for lung cancer: exon-7 mutation (4889 A to G), and a T to C mutation in the 3′-flanking region. Clin Investig 72: 240-248
7. Garte SJ, Trachman J, Crofts F, Toniolo P, Buxbaum J, Bayo S, Taioli E (1996) Distribution of composite CYP1A1 genotypes in Africans. African-Americans and Caucasians. Hum Hered 46: 121-127
8. Guengerich FP, Shimada T (1991) Oxidation of toxic and carcinogenic chemicals by human P450 enzymes. Chem Res Toxicol 4: 391-407
9. Hayashi SI, Watanabe J, Nakachi K, Kawajiri K (1991) Genetic linkage of lung cancer-associated MspI polymorphism with amino acid replacement in the heme binding region of the human cytochrome P4501A1 gene. J Biochem 110: 407-411
10. Hirvonen A, Husgafvel-Pursiainen K, Karjalainen A, Anttila S, Vainio H (1992) Point-mutational MspI and Ile-Val polymorphisms closely linked in the CYP1A1 gene: lack of association with susceptibility to lung cancer in a Finnish study population. Cancer Epidemiol Biomarkers Prev 1: 485-489
11. Kawajiri K, Nakachi K, Imai K, Yoshii A, Shinoda N, Watanabe J (1990) Identification of genetically high risk individuals to lung cancer by DNA polymorphism of cytochrome P4501A1 gene. FEBS Lett 263: 131-133
12. Lin HJ, Han CY, Lin BK, Hardy S (1994) Ethnic distribution of slow acetylator mutations in the polymorphic N-acetyltransferase (NAT2). Pharmacogenetics 4: 125-134
13. London SJ, Daly AK, Fairbrother KS, Holmes C, Carpenter CL, Bavidi C, Idle JR (1995) Lung cancer risk in African-Americans in relation to race-specific CYP1A1 polymorphism. Cancer Res 55: 6035-6037
14. Mrozikiewicz PM, Cascorbi I, Brockmöller J, Roots I (1997a) CYP1A1 mutations 4887A, 4889G, 5639C, and 6235C in the Polish population and their allelic linkage, determined by peptide nucleic acid-mediated PCR clamping. Pharmacogenetics 7: 303-307
15. Mrozikiewicz PM, Landt O, Cascorbi I, Roots I (1997b) Peptide nucleic acid-mediated polymerase chain reaction clamping allows allelic allocation of CYP1A1 mutations. Anal Biochem 250: 256-257
16. Nakachi K, Imai K, Hayashi S, Watanabe J, Kawajiri K (1991) Genetic susceptibility to squamous cell carcinoma of the lung in relation to cigarette smoking dose. Cancer Res 51: 5177-5180
17. Ørum H, Nielsen PE, Egholm M, Berg RH, Buchardt O, Stanley C (1993) Single base pair mutation analysis by PNA directed PCR clamping. Nucleic Acids Res 21: 5332-5336
18. Ou X, Ramos KS (1995) Regulation of cytochrome P4501A1 gene expression in vascular smooth muscle cells through aryl hydrocarbon receptor-mediated signal transduction requires a protein synthesis inhibitor. Arch Biochem Biophys 316: 116-122
19. Oyama T, Mitsudomi T, Kawamoto T, Ogami A, Osaki T, Kodama Y, Yasumoto K (1995) Detection of CYP1A1 gene polymorphism using designed RFLP and distributions of CYP1A1 genotypes in Japanese. Int Arch Occup Environ Health 67: 253-256
20. 32P-postlabeling and ELISA. Carcinogenesis 15: 557-560
21. Rojas M, Alexandrov K, Cascorbi I, Brockmöller J, Likhachev A, Pozharisski K, Bouvier G, Auburtin G, Mayer L, Koop-Schneider A, Roots I, Bartsch H (1998) High benzo(a)pyrene diol-epoxide DNA adduct levels in lung and blood cells from subjects with combined CYP1A1 MspI/MspI-GSTM1*0/*0 genotypes. Pharmacogenetics 8: (in press)
22. Sachse C, Brockmöller J, Bauer S, Roots I (1997) Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences. Am J Hum Genet 60: 284-295
23. Stegeman JJ, Hahn ME, Weisbrod R, Woodin BR, Joy JS, Najibi S, Cohen RA (1995) Induction of cytochrome P4501A1 by aryl hydrocarbon receptor agonists in porcine aorta endothelial cells in culture and cytochrome P4501A1 activity in intact cells. Mol Pharmacol 47: 296-306
24. Tefre T, Ryberg D, Haugen A, Nebert DW, Skaug V, Brogger A, Borresen AL (1991) Human CYP1A1 (cytodirome P(1)450) gene: lack of association between the MspI restriction fragment length polymorphism and incidence of lung cancer in a Norwegian population. Pharmacogenetics 1: 20-25
25. VanRollins M, Kaduce TL, Fang X, Knapp HR, Spector AA (1996) Arachidonic acid diols produced by cytochrome P450 monooxygenases are incorporated into phospholipids of vascular endothelial cells. J Biol Chem 271: 14001-14009
26. Wang SL, Huang J, Lai MD, Liu BH, Lai ML (1993) Molecular basis of genetic variation in debrisoquine hydroxylation in Chinese subjects: polymorphism in RFLP and DNA sequence of CYP2D6. Clin Pharmacol Ther 53: 410-418
27. 462: assessment of a role for the rare allele in carcinogenesis. Cancer Res 56: 3926-3933