CYP1A1 mutations 4887A, 4889G, 5639C and 6235C in the Polish population and their allelic linkage, determined by peptide nucleic acid-mediated PCR clamping

Pharmacogenetics

Volumn 7, Issue 4, 1997, Pages 303-307

  Mrozikiewicz, Przemyslaw M ^a   Cascorbi, Ingolf ^a   Brockmöller, Jürgen ^a   Roots, Ivar ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Cytochrome P 450 1A1; Ethnic differences; Mutation; Peptide nucleic acid; PNA

Indexed keywords

CYTOCHROME P450 ISOENZYME; PEPTIDE NUCLEIC ACID;

ADOLESCENT; ADULT; ALLELE; ARTICLE; CHILD; CONTROLLED STUDY; ETHNIC DIFFERENCE; FEMALE; GENE MUTATION; GENE SEQUENCE; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; POLAND; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

ADOLESCENT; ADULT; ALLELES; CHILD; CHILD, PRESCHOOL; CYTOCHROME P-450 CYP1A1; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; LINKAGE (GENETICS); MALE; MUTATION; OLIGODEOXYRIBONUCLEOTIDES; PEPTIDES; POLAND; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RANDOM ALLOCATION;

EID: 0030737697     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-199708000-00005     Document Type: Article

References (18)

1. Brockmöller J. Cascorbi I. Kerb R. Roots I. Combined analysis of inherited polymorphisms in arylamine N-acetyltransferase 2. glutathione S-transferase M1 and T1. microsomal epoxide hydrolase, and cytochrome P450 enzymes as modulators of bladder cancer risk. Cancer Res 1996: 56, 3915-3925.
2. Cascorbi I. Brockmöller J. Roots I. A C4887A polymorphism in exon 7 of human CYP1A1: population frequency. mutation linkages. and impact on lung cancer susceptibility. Cunrer Res 1946: 56, 4965-4969.
3. Crofts F. Cosma GN. Currie D. Taioli E. Toniolo P. Garte SJ. A novel CYP1A1 gene polymorphism in African-Americans. Carcinogenesis 1993: 14, 29-31.
4. Crofts F. Taioli E. Trachman J. Cosma GN. Currie D. Toniolo P. Garte SJ. Functional significance of different CYP1A1 genotypes. Carcinogenesis 1994: 15, 2691-2693.
5. Drakoulis N. Cascorbi I. Brockmöller J. Gross CR. Roots I. Polymorphisms in the human CYP1A1 gene as susceptibility factors for lung cancer: exon-7 mutation (4889 A to G1. and a T to C mutation in the 3′-flanking region. Clin Investig 1994: 72, 240-248.
6. Garte SJ. Trachman J. Crofts E. Toniolo P. Buxbaum J. Bayo S. Taioli E. Distribution of composite CYP1A1 genotypes in Africans. African-Americans and Caucasians. Hum Hered 1996: 46, 121-127.
7. Hayashi SI. Watanabe J. Nakachi K. KawaJiri K. Genetic linkage of lung cancer-associated Mspl polymorphism with amino acid replacement in the heme binding region of the human cytochrome P4501A1 gene. J Biochem 1991: 110, 407-411.
8. Hirvonen A. Husgafvel-Pursiainen K. KarJalainen A. Anttila S. Vainio H. Point-mutational Mspl and Ile-Val polymorphisms closely linked in the CYP1A1 gene: lack of association with susceptibility to lung cancer in a Finnish study population. Cancer Epidemiol Biomarkers Prev 1992: 1, 485-489.
9. KawaJiri K. Nakachi K. Imai K. Yoshii A. Shinoda N. Watanabe J. Identification of genetically high risk individuals to lung cancer by DNA polymorphism of cytochrome P4501A1 gene. FEBS Lett 1990: 263, 131-133.
10. KawaJiri K. Watanabe J. Gotoh O. Tagashira Y. Sogawa K. FuJii-Kuriyama Y. Structure and drug inducibility of the human cytochrome P-450c gene. Eur J Biochem 1986: 159, 219-225.
11. Kiyohara C, Hirohata T. Inutsuka S. The relationship between aryl hydrocarbon hydroxylase and polymorphisms of the CYP1A1 gene. Jpn J Cancer Res 1996: 87, 18-24.
12. Mrozikiewicz PM. Cascorbi I. Brockmöller J. Roots I. Determination and allelic allocation of seven nucleotide transitions within the arylamine N-acetyltransferase gene in the Polish population. Clin Pharmacol Ther 1996: 59, 376-382.
13. Mrozikiewicx PM. Landt O. Cascorbi I. Roots I. Peplide nucleic acid-mediated polymerase chain reaction clamping allows allelic allocation of CYP1A1 mutations. Anal Biochem 1997: 250. 56-257.
14. Nakachi K. Imai K. Hayashi S. Watanabe J. KawaJiri K. Genetic susceptibility to squamous cell carcinoma of the lung in relation to cigarette smoking dose. Cancer Res 1991: 51, 5177-5180.
15. Ørum H. Nielsen PE. Egholm M. Berg RH. Buchardt O. Stanley C. Single base pair mutation analysis by PNA directed PCR clamping. Nucl Acids Res 1993: 21, 5332-5336.
16. Taylor RM. Chinnery PF. Turnbull DM. Lightowlers RN. Selective inhibition of mutant human mitochondrial DNA replication in vitro by peptide nucleic acid. Nature Genetics 1997: 15, 212-215.
17. Tefre T. Ryberg D. Haugen A. Nebert DW. Skaug V. Brogger A. Borresen AL. Human CYP1A1 (cytochrome P(1)450) gene: lack of association between the Msp1 restriction fragment length polymorphism and incidence of lung cancer in a Norwegian population. Pharmacogenetics 1991: l, 20-25.
18. 462: assessment of a role for the rare allele in carcinogcnesis. Cancer Res 1996: 56, 926-3933.