Immunization onto bare skin with heat-labile enterotoxin of Escherichia coli enhances immune responses to coadministered protein and peptide antigens and protects mice against lethal toxin challenge

Immunology

Volumn 102, Issue 3, 2001, Pages 344-351

  Beignon, A S ^a   Briand, J P ^a   Muller, S ^a   Partidos, C D ^a  

^a CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; BETA GALACTOSIDASE; CHOLERA TOXIN; EPITOPE; ESCHERICHIA COLI ENTEROTOXIN; GANGLIOSIDE GM1; HEMAGGLUTININ; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 2;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; BACTERIAL INFECTION; CONTROLLED STUDY; ESCHERICHIA COLI; FEMALE; HELPER CELL; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOGENICITY; INFLUENZA VIRUS; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; THERMOSTABILITY; TOXIN ANALYSIS; VACCINATION; VAGINA DISCHARGE;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, CUTANEOUS; ANIMALS; ANTIBODIES, BACTERIAL; BACTERIAL TOXINS; CELL DIVISION; CHOLERA TOXIN; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; ENTEROTOXINS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; FEMALE; G(M1) GANGLIOSIDE; IMMUNITY, MUCOSAL; IMMUNIZATION; IMMUNOGLOBULIN A, SECRETORY; IMMUNOGLOBULIN G; MICE; MICE, INBRED BALB C; SPLEEN;

EID: 0035074385     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.2001.01183.x     Document Type: Article

References (31)

1. The skin as a barrier: Structure and function
2. The skin immune system. Its cellular constituents and their interactions
3. Role of cytokines in epidermal Langerhans cell migration
4. Migration of Langerhans cells and dermal dendritic cells in skin organ cultures: Augmentation by TNFα and IL-1β
5. The role of dendritic cells in cutaneous immunity
6. Skin immunisation made possible by cholera toxin
7. Transcutaneous immunisation with bacterial ADP-ribosylating exotoxins as antigens and adjuvants
8. Percutaneous peptide immunization via corneum barrier-disrupted murine skin for experimental tumor immunoprophylaxis
9. Immunisation via hair follicles by topical application of naked DNA to normal skin
10. The 500 Dalton rule for the skin penetration of chemical compounds and drugs
11. Transcutaneous immunisation with cholera toxin protects mice against lethal mucosal toxin challenge
12. Principles of transcutaneous immunisation using cholera toxin as an adjuvant
13. Intranasal vaccines: Forthcoming challenges
14. Structure and function of cholera toxin and the related Escherichia coli heat-labile enterotoxin
15. Epidemiology of diarrheal disease: Implications for control by vaccines
16. Local and systemic antibody responses to naturally acquired enterotoxigenic Escherichia coli diarrhoea in an endemic area
17. Transmission of hepatitis B, hepatitis C and human immunodeficiency viruses through unsafe injections in the developing world: Model-based regional estimates
18. On the interaction of promiscuous antigenic peptides with different DR alleles. Identification of common structural motifs
19. CpG DNA is a potent enhancer of specific immunity in mice immunised with recombinant hepatitis B surface antigen
20. Effects of estrous cycle on local immune responses and protection of intranasally immunized mice against HSV type II infection in the genital tract
21. Comparison of receptors for cholera and Escherichia coli enterotoxin in human intestine
22. Role of GM1 binding in the mucosal immunogenicity and adjuvant activity of the Escherichia coli heat-labile enterotoxin and its B subunit
23. CpG motifs in bacterial DNA trigger direct B-cell activation
24. CpG motifs expressed by bacterial DNA rapidly induce lymphocytes to secret IL-6, IL-I2 and INF-γ
25. CpG-rich islands and the function of DNA methylation
26. Immunostimulatory DNA sequences function as T helper 1 promoting adjuvants
27. CpG motifs induce Langerhans cell migration in vivo
28. Regulation of murine airway eosinophilia and Th2 cells by antigen-conjugated CpG oligodeoxynucleotides as a novel antigen-specific immunomodulator
29. Conjugation of protein to immunostimulatory DNA results in a rapid, long-lasting and potent induction of cell-mediated and humoral immunity
30. Anti-peptide antibody responses following intranasal immunisation: Effectiveness of mucosal adjuvants
31. Activation of cutaneous dendritic cells by CpG containing oligonucleotides: A role for dendritic cells in the augmentation of Th1 responses by immunostimulatory DNA