FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands

EMBO Journal

Volumn 16, Issue 9, 1997, Pages 2376-2383

  Bedford, Mark T ^a   Chan, David C ^a,b   Leder, Philip ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

Formin binding protein; Proline rich; SH3 domain; WW domain

Indexed keywords

BINDING PROTEIN; LIGAND; METHENAMINE; PROLINE;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CONSENSUS SEQUENCE; GENETIC CONSERVATION; LIGAND BINDING; LIMB BUD; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BINDING SITES; CARRIER PROTEINS; CONSENSUS SEQUENCE; CROSS REACTIONS; FETAL PROTEINS; LIGANDS; MICE; MICROFILAMENT PROTEINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NUCLEAR PROTEINS; ONCOGENE PROTEINS V-ABL; PHOSPHOPROTEINS; PROLINE; PROTEIN BINDING; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-FYN; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0030910308     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.9.2376     Document Type: Article

References (46)

1. Andre, B. and Springael, J.Y. (1994) WWP, a new amino acid motif present in single or multiple copies in various proteins including dystrophin and the SH3-binding Yes-associated protein YAP65. Biochem. Biophvs. Res. Commun., 205, 1201-1205.
2. Bar-Sagi, D., Rotin, D., Batzer, A., Mandiyan, V. and Schlessinger, J. (1993) SH3 domains direct cellular localization of signaling molecules. Cell, 74, 83-91.
3. Bork, P. and Margolis, B. (1995) A phosphotyrosine interaction domain [letter]. Cell, 80, 693-694.
4. Bork, P. and Sudol, M. (1994) The WW domain: a signalling site in dystrophin? Trends Biochem. Sci., 19, 531-533.
5. Cahir McFarland, E.D. and Thomas, M.L. (1995) CD45 protein-tyrosine phosphatase associates with the WW domain-containing protein, CD45AP, through the transmembrane region. J. Biol. Chem., 270, 28103-28107.
6. Chan, D.C. and Leder, P. (1996) Genetic evidence that formins function within the nucleus. J. Biol. Chem., 271, 23472-23477.
7. Chan, D.C., Bedford, M.T. and Leder, P. (1996) Formin binding proteins bear WWP/WW domains that bind proline-rich peptides and functionally resemble SH3 domains. EMBO J., 15, 1045-1054.
8. Chen, H.I. and Sudol, M. (1995) The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules. Proc. Natl Acad. Sci. USA, 92, 7819-7823.
9. Einbond, A. and Sudol, M. (1996) Towards prediction of cognate complexes between the WW domain and proline-rich ligands. FEBS Lett., 384, 1-8.
10. Ferguson, K.M., Lemmon, M.A., Sigler, P.B. and Schlessinger, J. (1995) Scratching the surface with the PH domain. Nature Struct. Biol., 2, 715-718.
11. Fiore, F., Zambrano, N., Minopoli, G., Donini, V., Duilio, A. and Russo, T. (1995) The regions of the Fe65 protein homologous to the phosphotyrosine interaction/phosphotyrosine binding domain of She bind the intracellular domain of the Alzheimer's amyloid precursor protein. J. Biol. Chem., 270, 30853-30856.
12. Freeman, N.L., Lila, T., Mintzer, K.A., Chen, Z., Pahk, A.J., Ren, R., Drubin, D.G. and Field, J. (1996) A conserved proline-rich region of the Saccharomyces cerevisiae cyclase-associated protein binds SH3 domains and modulates cytoskeletal localization. Mol. Cell. Biol., 16, 548-556.
13. Gout, I. et al. (1993) The GTPase dynamin binds to and is activated by a subset of SH3 domains. Cell, 75, 25-36.
14. Gui, J.F., Tronchere, H., Chandler, S.D. and Fu, X.D. (1994a) Purification and characterization of a kinase specific for the serine- and arginine-rich pre-mRNA splicing factors. Proc. Natl Acad. Sci. USA, 91, 10824-10828.
15. Gui, J.F., Lane, W.S. and Fu, X.D. (1994b) A serine kinase regulates intracellular localization of splicing factors in the cell cycle. Nature, 369, 678-682.
16. Harlow, E. and Lane, D. (1988) Antibodies: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
17. Hofmann, K. and Bucher, P. (1995) The rsp5-domain is shared by proteins of diverse function. FEBS Lett., 358, 153-157.
18. Jung, D., Yang, B., Meyer, J., Chamberlain, J.S. and Campbell, K.P. (1995) Identification and characterization of the dystrophin anchoring site on beta-dystroglycan. J. Biol. Chem., 270, 27305-27310.
19. Kaelin, W.G. et al. (1992) Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties. Cell, 70, 351-364.
20. Kao, H. and Siliciano, P.G. (1996) Identification of Prp40, a novel essential yeast splicing factor associated with the U1 small nuclear ribonucleoprotein particle. Mol. Cell. Biol., 16, 960-967.
21. Ladbury, J.E., Lemmon, M.A., Zhou, M., Green, J., Botfield, M.C. and Schlessinger, J. (1995) Measurement of the binding of tyrosyl phosphopeptides to SH2 domains: a reappraisal. Proc. Natl Acad. Sci. USA, 92, 3199-3230.
22. Lewis, J.D., Meehan, R.R., Henzel, W.J., Maurer-Fogy, I., Jeppesen, P., Klein, F. and Bird, A. (1992) Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA. Cell, 69, 905-914.
23. Lu, K.P., Hanes, S.D. and Hunter, T. (1996) A human peptidyl-prolyl isomerase essential for regulation of mitosis. Nature, 380, 544-547.
24. Macias, M.J., Hyvonen, M., Baraldi, E., Schultz, J., Sudol, M., Saraste, M. and Oschkinat, H. (1996) The structure of the WW domain in complex with a proline-rich peptide. Nature, 382, 646-649.
25. Maleszka, R., Hanes, S.D., Hackett, R.L., de Couet, H.G. and Miklos, G.L. (1996) The Drosophila melanogaster dodo (dod) gene, conserved in humans, is functionally interchangeable with the ESS1 cell division gene of Saccharomyces cerevisiae. Proc. Natl Acad. Sci. USA, 93, 447-451.
26. Marengere, L.E. and Pawson, T. (1994) Structure and function of SH2 domains. J. Cell Sci. Suppl., 18, 97-104.
27. Morinaga, T., Yasuda, H., Hashimoto, T., Higashio, K. and Tamaoki, T. (1991) A human alpha-fetoprotein enhancer-binding protein, ATBF1, contains four homeodomains and seventeen zinc fingers. Mol. Cell. Biol., 11, 6041-6049.
28. Musacchio, A., Wilmanns, M. and Saraste, M. (1994) Structure and function of the SH3 domain. Prog. Biophys. Mol. Biol., 61, 283-297.
29. Nan, X., Tate, P., Li, E. and Bird, A. (1996) DNA methylation specifies chromosomal localization of MeCP2. Mol. Cell. Biol., 16, 414-421.
30. Panayotou, G., Gish, G., End, P., Truong, O., Gout, I., Dhand, R., Fry, M.J., Miles, I., Pawson, T. and Waterfield, M.D. (1993) Interactions between SH2 domains and tyrosine-phosphorylated platelet-derived growth factor beta-receptor sequences: analysis of kinetic parameters by a novel biosensor-based approach. Mol. Cell. Biol., 13, 3567-3576.
31. Ren, R., Mayer, B.J., Cicchetti, P. and Baltimore, D. (1993) Identification of a ten-amino acid proline-rich SH3 binding site. Science, 259, 1157-1161.
32. Rickles, R.J., Botfield, M.C., Weng, Z., Taylor, J.A., Green, O.M., Brugge, J.S. and Zoller, M.J. (1994) Identification of Src, Fyn, Lyn, PI3K and Abl SH3 domain ligands using phage display libraries. EMBO J., 13, 5598-5604.
33. Sazuka, T., Tomooka, Y., Kathju, S., Ikawa, Y., Noda, M. and Kumar, S. (1992) Identification of a developmentally regulated gene in the mouse central nervous system which encodes a novel proline rich protein. Biochim. Biophys. Acta, 1132, 240-248.
34. Schild, L., Lu, Y., Gautschi, I., Schneeberger, E., Lifton, R.P. and Rossier, B.C. (1996) Identification of a PY motif in the epithelial Na channel subunits as a target sequence for mutations causing channel activation found in Liddle syndrome. EMBO J., 15, 2381-2387.
35. Sparks, A.B., Rider, J.E., Hoffman, N.G., Fowlkes, D.M., Quilliam, L.A. and Kay, B.K. (1996) Distinct ligand preferences of Src homology 3 domains from Src, Yes, Abl, Contactin, p53bp2, PLCγ, Crk, and Grab2. Proc. Natl Acad. Sci. USA, 93, 1540-1544.
36. Staub, O. and Rotin, D. (1996) WW domains. Structure, 4, 495-499.
37. + channel deleted in Liddle's syndrome. EMBO J., 15, 2371-2380.
38. Sudol, M. (1996) The WW module competes with the SH3 domain? Trends Biochem. Sci., 21, 161-163.
39. Sudol, M., Bork, P., Einbond, A., Kastury, K., Druck, T., Negrini, M., Huebner, K. and Lehman, D. (1995) Characterization of the mammalian YAP (Yes-associated protein) gene and its role in defining a novel protein module, the WW domain. J. Biol. Chem., 270, 14733-14741.
40. Tate, P., Skarnes, W. and Bird, A. (1996) The methyl-CpG binding protein MeCP2 is essential for embryonic development in the mouse. Nature Genet., 12, 205-208.
41. Toda, T., Iida, A., Miwa, T., Nakamura, Y. and Imai, T. (1994) Isolation and characterization of a novel gene encoding nuclear protein at a locus (D11S636) tightly linked to multiple endocrine neoplasia type 1 (MEN1). Hum. Mol. Genet., 3, 465-470.
42. Trumpp, A., Blundell, P.A., de la Pompa, J.L. and Zeller, R. (1992) The chicken limb deformity gene encodes nuclear proteins expressed in specific cell types during morphogenesis. Genes Dev., 6, 14-28.
43. Woychik, R.P., Stewart, T.A., Davis, L.G., D'Eustachio, P. and Leder, P. (1985) An inherited limb deformity created by insertional mutagenesis in a transgenic mouse. Nature, 318, 36-40.
44. Woychik, R.P. Maas, R.L., Zeller, R., Vogt, T.F. and Leder, P. (1990) 'Formins': proteins deduced from the alternative transcripts of the limb deformity gene. Nature, 346, 850-853.
45. Yasuda, H., Mizuno, A., Tamaoki, T. and Morinaga, T. (1994) ATBF1, a multiple-homeodomain zinc finger protein, selectively down-regulates AT-rich elements of the human alpha-fetoprotein gene. Mol. Cell. Biol., 14, 1395-1401.
46. Zheng, J., Cahill, S.M., Lemmon, M.A., Fushman, D., Schlessinger, J. and Cowburn, D. (1996) Identification of the binding site for acidic phospholipids on the PH domain of dynamin: implications for stimulation of GTPase activity. J. Mol. Biol., 255, 14-21.