Formin binding proteins bear WWP/WW domains that bind proline-rich peptides and functionally resemble SH3 domains

EMBO Journal

Volumn 15, Issue 5, 1996, Pages 1045-1054

  Chan, David C ^a   Bedford, Mark T ^b   Leder, Philip ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Limb deformity; SH3 domains; WWP domains

Indexed keywords

BINDING PROTEIN; METHENAMINE; PEPTIDE; PROLINE;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BINDING COMPETITION; CONSENSUS SEQUENCE; KIDNEY DEVELOPMENT; LIMB BUD; LIMB DEVELOPMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; SEQUENCE HOMOLOGY;

ANIMALIA; MURINAE;

EID: 0029981652     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00442.x     Document Type: Article

References (44)

1. Alexandropoulos, K., Cheng, G. and Baltimore, D. (1995) Proline-rich sequences that bind to Src homology 3 domains with individual specificities. Proc. Natl Acad. Sci. USA, 92, 3110-3114.
2. André, B. and Springael, J.-Y. (1994) WWP, a new amino acid motif present in single or multiple copies in various proteins including dystrophin and the SH3-binding Yes-associated protein YAP65. Biochem. Biophys Res. Commun., 205, 1202-1205.
3. Bork, P. and Margolis, B. (1995) A phosphotyrosine interaction domain. Cell, 80, 693-694.
4. Bork, P. and Sudol, M. (1994) The WW domain: a signalling site in dystrophin? Trends Biochem. Sci., 19, 531-533.
5. Chan, D.C., Wynshaw-Boris, A. and Leder, P. (1995) Formin isoforms are differentially expressed in the mouse embryo and are required for normal expression of fgf-4 and shh in the limb bud. Development, 121, 3151-3162.
6. Chen, H.I. and Sudol, M. (1995) The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules. Proc. Natl Acad. Sci. USA, 92, 7819-7823.
7. Chenevert, J., Corrado, K., Bender, A., Pringle, J. and Herskowitz, I. (1992) A yeast gene (BEM1) necessary for cell polarization whose product contains two SH3 domains. Nature, 356, 77-79.
8. Cicchetti, P., Mayer, B.J., Thiel, G. and Baltimore, D. (1992) Identification of a protein that binds to the SH3 region of Abl and is similar to Bcr and GAP-rho. Science, 257, 803-806.
9. Clark, S.G., Stern, M J. and Horvitz, H R. (1992) C. elegans cell-signaling gene sem-5 encodes a protein with SH2 and SH3 domains. Nature, 356, 340-344.
10. Cohen, G.B., Ren, R. and Baltimore, D. (1995) Modular binding domains in signal transduction proteins. Cell, 80, 237-248.
11. Egan, S.E., Giddings, B.W., Brooks, M.W., Buday, L., Sizeland, A.M. and Weinberg, R.A. (1993) Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation. Nature, 363, 45-51.
12. Feng, S., Chen, J.K., Yu, H., Simon, J.A. and Schreiber, S.L. (1994) Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions. Science, 266, 1241-1247.
13. Grant, S.G., O'Dell, T.J., Karl, K.A., Stein, P.L., Soriano, P. and Kandel, E.R. (1992) Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice. Science, 258, 1903-1910.
14. Harlow, E. and Lane, D. (1988) Antibodies: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
15. Huibregtse, J.M , Scheffner, M , Beaudenon, S and Howley, P.M. (1995) A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase. Proc. Natl Acad. Sci. USA, 92, 2563-2567.
16. Jackson-Grusby, L., Kuo, A. and Leder, P. (1992) A variant limb deformity transcript expressed in the embryonic mouse limb defines a novel formin. Genes Dev., 6, 29-37.
17. Kaelin, W.G. et al. (1992) Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties. Cell. 70, 351-364.
18. Kavanaugh, W.M., Turck, C.W. and Williams, L.T. (1995) PTB domain binding to signaling proteins through a sequence motif containing phosphotyrosine. Science, 268, 1177-1179.
19. King, R. W., Peters, J -M., Tugendreich, S., Rolfe, M., Heiter, P. and Kirschner, M.W. (1995) A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B. Cell, 81, 279-288.
20. Kohda, D., Hatanaka, H., Odaka, M., Mandiyan, V., Ullrich, A., Schlessinger, J. and Inagaki, F. (1993) Solution structure of the SH3 domain of phospholipase C-γ. Cell, 72, 953-960.
21. Lee, J.W., Choi, H.S., Gyuris, J., Brent, R. and Moore, D.D. (1995) Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor. Mol. Endocrinol., 9, 243-254.
22. Lowenstein, E.J. et al. (1992) The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling. Cell, 70, 431-442.
23. Maas, R., Elfering, S., Glaser, T. and Jepeal, L. (1994) Deficient outgrowth of the ureteric bud underlies the renal agenesis phenotype in mice manifesting the limb deformity (Id) mutation. Dev. Dynam., 199, 214-228.
24. Musacchio, A., Martin, N., Pauptit, R., Wierenga, R. and Saraste, M. (1992) Crystal structure of a Src-homology 3 (SH3) domain. Nature, 359, 851-855.
25. Musacchio, A., Wilmanns, M. and Saraste, M. (1994) Structure and function of the SH3 domain. Prog. Biophys. Mol. Biol., 61, 283-297.
26. Pascolo, S., Ghazvini, M., Boyer, J., Colleaux, L., Thierry, A. and Dujon, B. (1992) The sequence of a 9.3 kb segment located on the left arm of the yeast chromosome XI reveals five open reading frames including the CCE1 gene and putative products related to MYO2 and to the ribosomal protein L10. Yeast, 8, 987-995
27. Ren, R, Mayer, B.J., Cicchetti, P. and Baltimore, D. (1993) Identification of a ten-amino acid proline-rich SH3 binding site. Science, 259, 1157-1161.
28. Rozakis-Adcock, M., Fernley, R., Wade, J., Pawson, T. and Bowtell, D. (1993) The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1. Nature, 363, 83-85.
29. Ruden, D.M., Ma, J., Li, Y., Wood, K. and Ptashne, M. (1991) Generating yeast transcriptional activators containing no yeast protein sequences. Nature, 350, 426-430.
30. ml mutation show poor viability and depletion of selected B and T cell populations. Cell, 65, 1165-1175.
31. Simon, M.A., Dodson, G.S. and Rubin, G.M. (1993) An SH3-SH2-SH3 protein is required for p21Ras1 activation and binds to Sevenless and Sos proteins in vitro. Cell, 73, 169-177.
32. Soriano, P., Montgomery, C., Geske, R. and Bradley, A. (1991) Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice Cell, 64, 693-702.
33. Sudol, M., Bork, P., Eindond, A., Kastury, K., Druck, T., Negrini, M., Huebner, K. and Lehman, D. (1995) Characterization of the mammalian YAP (Yes-associated protein) gene and its role in defining a novel protein module, the WW domain. J. Biol. Chem., 270, 14733-14741.
34. Sulston, J. et al. (1992) The C. elegans genome sequencing project: A beginning. Nature, 356, 37-41
35. Trumpp, A., Blundell, P.A., de la Pompa, J L. and Zeller, R. (1992) The chicken limb deformity (ld) gene encodes nuclear proteins expressed in specific cell types during morphogenesis. Genes Dev., 6, 14-28.
36. Tybulewicz, V.L.J., Crawford, C.E., Jackson, P.K., Bronson, R.T. and Mulligan, R.C. (1991) Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene. Cell, 65, 1153-1163.
37. Vogt, T.F., Jackson-Grusby, L., Rush, J. and Leder, P. (1993) Formins. Phosphoprotein isoforms encoded by the mouse limb deformity locus. Proc. Natl Acad. Sci. USA, 90, 5554-5558.
38. Woychik, R.P., Stewart, T.A., Davis, L.G., D'Eustachio, P. and Leder, P. (1985) An inherited limb deformity created by insertional mutagenesis in a transgenic mouse. Nature, 318, 36-40.
39. Woychik, R.P., Maas, R.L, Zeller, R., Vogt, T.F. and Leder, P. (1990) 'Formins': proteins deduced from the alternative transcripts of the limb deformity gene. Nature, 346, 850-853.
40. src substrate. Mol. Cell. Biol., 11, 5113-5124.
41. Yagi, T., Aizawa, S., Tokunaga, T., Shigetam, Y., Takeda, N. and Ikawa, Y. (1993) A role for fyn tyrosine kinase in the suckling behaviour of neonatal mice. Nature, 366, 742-745.
42. Yu, H., Rosen, M.K., Shin, T.B., Seidel-Dugan, C., Brugge, J.S. and Schreiber, S L. (1992) Solution structure of the SH3 domain of src and identification of its ligand-binding site. Science, 258, 1665-1668.
43. Zeller, R., Jackson-Grusby, L. and Leder, P. (1989) The limb deformity gene is required for apical ectodermal ridge differentiation and anteroposterior limb pattern formation. Genes Dev., 3, 1481-1492.
44. Zhan, X., Plourde, C., Hu, X., Friesel, R. and Maciag, T. (1994) Association of fibroblast growth factor receptor-1 with c-Src correlates with association between c-Src and cortactin. J. Biol. Chem., 269, 20221-20224