Ctf7p is essential for sister chromatid cohesion and links mitotic chromosome structure to the DNA replication machinery

Genes and Development

Volumn 13, Issue 3, 1999, Pages 307-319

  Skibbens, Robert V ^a,c   Corson, Laura B ^b   Koshland, Doug ^c   Hieter, Philip ^a,d  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c GEOPHYSICAL LABORATORY   (United States)

^d UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

BUB3; Chromatid cohesion; Chromosome loss; Condensation; CTF7; MAD2; POL30

Indexed keywords

CTF7P; CYCLINE; DNA; NUCLEAR PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CELL CYCLE S PHASE; CHROMOSOME CONDENSATION; CHROMOSOME LOSS; CHROMOSOME STRUCTURE; CONTROLLED STUDY; DNA METABOLISM; DNA REPLICATION; FLUORESCENCE IN SITU HYBRIDIZATION; MITOSIS; MITOSIS SPINDLE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SISTER CHROMATID; TEMPERATURE SENSITIVITY;

SACCHAROMYCES CEREVISIAE; SACCHAROMYCETALES;

EID: 0033082232     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.13.3.307     Document Type: Article

References (65)

1. Amin, N.S. and C. Holm. 1996. In vivo analysis reveals that the interdomain region of the yeast proliferating cell nuclear antigen is important for DNA replication and DNA repair. Genetics 144: 479-493.
2. Ayyagari, R., K.J. Impellizzeri, B.L. Yoder, S.L. Gary, and P.M. Burgers. 1995. A mutational analysis of the yeast proliferating cell nuclear antigen indicates distinct roles in DNA replication and DNA repair. Mol. Cell Biol. 15: 4420-4429.
3. Baudin, A., O. Ozier-Kalogeropoulos, A. Denouel, F. Lacroute, and C. Cullin. 1993. A simple and efficient method for direct gene deletion in Saccharomyces cerevisiae. Nucleic Acids Res. 21: 3329-3330.
4. Bauer, G.A. and P.M. Burgers. 1990. Molecular cloning, structure and expression of the yeast proliferating cell nuclear antigen gene. Nucleic Acids Res. 18: 261-265.
5. Boeke, J.D., J. Trueheart, G. Natsoulis, and G.R. Fink. 1987. 5-Fluoroorotic acid as a selective agent in yeast molecular genetics. Methods Enzymol. 154: 164-175.
6. Brachmann, C.B., J.M. Sherman, S.E. Devine, E.E. Cameron, L. Pillus and J.D. Boeke. 1995. The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability. Genes &Dev. 9: 2888-2902.
7. Burgers, P.M. 1988. Mammalian cyclin/PCNA [DNA polymerase delta auxiliary protein] stimulates processive DNA synthesis by yeast DNA polymerase III. Nucleic Acids Res. 16: 6297-6307.
8. _. 1991. Saccharomyces cerevisiae replication factor C. II. Formation and activity of complexes with the proliferating cell nuclear antigen and with DNA polymerases delta and epsilon. J. Biol. Chem. 266: 22698-22706.
9. Castano, I.B., P.M. Brzoska, B.U. Sadoff, H. Chen, and M.F. Christman. 1996. Mitotic chromosome condensation in the rDNA requires TRF4 and DNA topoisomerase I in Saccharomyces cerevisiae. Genes & Dev. 10: 2564-2576.
10. Chuang, P.-T., D.G. Albertson, and B.J. Meyer. 1994. DPY-27: A chromosome condensation protein homolog that regulates C. elegans dosage compensation through association with the X chromosome. Cell 79: 459-474.
11. Ciosk, R., W. Zachariae, C. Michaelis, A. Shevchenko, M. Mann, and K. Nasmyth. 1998. An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast. Cell 93: 1067-1076.
12. Cohen-Fix, O., J.M. Peters, M.W. Kirschner, and D. Koshland. 1996. Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p. Genes & Dev. 10: 3081-3093.
13. Connelly, C. and P. Hieter. 1996. Budding yeast SKP1 encodes an evolutionarily conserved kinetochore protein required for cell cycle progression. Cell 86: 275-285.
14. Doheny, K.F., P.K. Sorger, A.A. Hyman, S. Tugendreich, F. Spencer, and P. Hieter. 1993. Identification of essential components of the S. cerevisiae kinetochore. Cell 73: 761-774.
15. Funabiki, H., K. Kumada, and M. Yanagida. 1996. Fission yeast Cut1 and Cut2 are essential for sister chromatid separation, concentrate along the metaphase spindle and form large complexes. EMBO J. 15: 6617-6628.
16. 1 phase. Genes & Dev. 12: 3408-3418.
17. Gerring, S.L., F. Spencer, and P. Hieter. 1990. The CHL1 (CTF1) gene product of Saccharomyces cerevisiae is important for chromosome transmission and normal cell cycle progression in G2/M. EMBO J. 9: 4347-4358.
18. Goh, P.Y. and J.V. Kilmartin. 1993. NDC10: A gene involved in chromosome segregation in Saccharomyces cerevisiae. J. Cell Biol. 121: 503-512.
19. Guacci, V., E. Hogan, and D. Koshland. 1994. Chromosome condensation and sister chromatid pairing in budding yeast. J. Cell Biol. 125: 517-530.
20. Guacci, V., D. Koshland, and A. Strunnikov. 1997. A direct link between sister chromatid cohesion and chromosome condensation revealed through the analysis of MCD1 in S. cerevisiae. Cell 91: 47-57.
21. Hirano, T. and T.J. Mitchison. 1994. A heterodimeric coiled-coil protein required for mitotic chromosome condensation in vitro. Cell 79: 449-458.
22. Hirano, T., R. Kobayashi, and M. Hirano. 1997. Condensins, chromosome condensation protein complexes containing XCAP-C, XCAP-E and a Xenopus homolog of the Drosophila Barren protein. Cell 89: 511-521.
23. Hoyt, M.A., L. Totis, and B.T. Roberts. 1991. S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function. Cell 66: 507-517.
24. Hyman, A.A. and P.K. Sorger. 1995. Structure and function of kinetochores in budding yeast. Annu. Rev. Cell Dev. Biol 11: 471-495.
25. Ito, H., Y. Fukuda, K. Murata, and A. Kimura. 1983. Transformation of intact yeast cells treated with alkali cations. J. Bacteriol. 153: 163-168.
26. Jessberger, R., B. Riwar, H. Baechtold, and A. Akhmedov. 1996. SMC proteins constitute two subunits of the mammalian recombination complex RC-1. EMBO J. 15: 4061-4068.
27. Jiang, W., J. Lechner, and J. Carbon. 1993. Isolation and characterization of a gene (CBF2) specifying a protein component of the budding yeast kinetochore. J. Cell Biol. 121: 513-519.
28. Johnston, L.H. and N.F. Lowndes. 1992. Cell cycle control of DNA synthesis in budding yeast. Nucleic Acids Res. 20: 2403-2410.
29. Kassenbrock, C.K., W. Cao, and M.G. Douglas. 1993. Genetic and biochemical characterization of ISP6, a small mitochondrial outer membrane protein associated with the protein translocation complex. EMBO J. 12: 3023-3034.
30. Kelman, Z. 1997. PCNA: Structure, functions and interactions. Oncogene 14: 629-640.
31. Koshland, D. and A. Strunnikov. 1996. Mitotic chromosome condensation. Annu. Rev. Cell Dev. Biol. 12: 305-333.
32. Kouprina, N., E. Kroll, A. Kirillov, V. Bannikov, V. Zakharyev, and V. Larionov. 1994. CHL12, a gene essential for the fidelity of chromosome transmission in the yeast Saccharomyces cerevisiae. Genetics 138: 1067-1079.
33. Krishna, T.S., X.P. Kong, S. Gary, P.M. Burgers, and J. Kuriyan. 1994. Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA. Cell 79: 1233-1243.
34. Lechner, J. and J. Carbon. 1991. A 240 kd multisubunit protein complex, CBF3, is a major component of the budding yeast centromere. Cell 64: 717-725.
35. Li, R. and A.W. Murray. 1991. Feedback control of mitosis in budding yeast. Cell 66: 519-531.
36. Losada, A., M. Hirano, and T. Hirano. 1998. Identification of Xenopus SMC protein complexes required for sister chromatid cohesion. Genes & Dev. 12: 1986-1997.
37. Michaelis, C., R. Ciosk, and K. Nasmyth. 1997. Cohesins: Chromosomal proteins that prevent premature separation of sister chromatids. Cell 91: 35-45.
38. Morrow, D.M., D.A. Tagle, Y. Shiloh, F.S. Collins, and P. Hieter. 1995. TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1. Cell 82: 831-840.
39. Murakami, Y., M. Naitou, H. Hagiwara, T. Shihata, M. Ozawa, S.-I. Sasanuma, Y. Tsuchiya, E. Soeda, K. Yokoyama, M. Yamazaki, H. Tashiro, and T. Eki. 1995. Analysis of the nucleotide sequence of chromosome VI from saccharomyces cervisiae. Nature Genet. 10: 261-268.
40. Neiman, A.M., B.J. Stevenson, H.P. Xu, G.F. Sprague Jr., I. Herskowitz, M. Wigler, and S. Marcus. 1993. Functional homology of protein kinases required for sexual differentiation in Schizosaccharomyces pombe and Saccharomyces cerevisiae suggests a conserved signal transduction module in eukaryotic organisms. Mol. Biol. Cell. 4: 107-120.
41. Nicklas, R.B. 1997. How cells get the right chromosomes. Science 275: 632-637.
42. O'Toole, E.T., D.N. Mastronarde, T.H. Giddings Jr., M. Winey, D.J. Burke, and J.R. McIntosh. 1997. Three-dimensional analysis and ultrastructural design of mitotic spindles from the cdc20 mutant of Saccharomyces cerevisiae. Mol. Biol. Cell 8: 1-11.
43. Pangilinan, F. and F. Spencer. 1996. Abnormal kinetochore structure activates the spindle assembly checkpoint in budding yeast. Mol. Biol. Cell 7: 1195-1208.
44. Paulovich, A.C. and L.H. Hartwell. 1995. A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage. Cell 82: 841-847.
45. Rieder C.L. and E.D. Salmon. 1994. Motile kinetochores and polar ejection forces dictate chromosome position. J. Cell Biol. 124: 223-233.
46. Rose, M.D., F. Winston, and P. Hieter 1990. Methods in yeast genetics. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
47. Saitoh, N., I.G. Goldberg, E.R. Wood, and W.C. Earnshaw. 1994. ScII: An abundant chromosome scaffold protein is a member of a family of putative ATPases with an unusual predicted tertiary structure. J. Cell Biol. 127: 303-318.
48. Saka, Y., T. Sutani, Y. Yamashita, S. Saitoh, M. Takeuchi, Y. Nakaseko, and M. Yanagida. 1994. Fission yeast cut3 and cut14, members of a ubiquitous protein family, are required for chromosome condensation and segregation in mitosis. EMBO J. 13: 4938-4952.
49. Schiestl, R.H. and R.D. Gietz. 1989. High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier. Curr. Genet. 16: 339-346.
50. Selig, S., K. Okumura, D.C. Ward, and H. Cedar. 1992. Delineation of DNA replication time zones by fluorescence in situ hybridization. EMBO J. 11: 1217-1225.
51. Sikorski, R.S. and P. Hieter. 1989. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122: 19-27.
52. Skibbens, R.V. and P. Hieter. 1998. Kinetochores and the checkpoint mechanism that monitors for defects in the chromosome segregation machinery. Annu. Rev. Genet. (in press).
53. Spencer, F., S.L. Gerring, C. Connelly, and P. Hieter. 1990. Mitotic chromosome transmission fidelity mutants in Saccharomyces cerevisiae. Genetics 124: 237-249.
54. Strunnikov, A.V., V.L. Larionov, and D. Koshland. 1993. SMC1: An essential yeast gene encoding a putative head-rod-tail protein is required for nuclear division and defines a new ubiquitous protein family. J. Cell Biol. 123: 1635-1648.
55. Strunnikov, A.V., E. Hogan, and D. Koshland. 1995. SMC2, a Sacchammyces cerevisiae gene essential for chromosome segregation and condensation, defines a subgroup within the SMC family. Genes & Dev. 9: 587-599.
56. Sumner, A.T. 1991. Scanning electron microscopy of mammalian chromosomes from prophase to telophase. Chromosoma 100: 410-418.
57. Sutani, T. and M. Yanagida. 1997. DNA renaturation activity of the SMC complex implicated in chromosome condensation. Nature 388: 798-801.
58. Toyn, J.H., A.L. Johnson, and L.H. Johnston. 1995. Segregation of unreplicated chromosomes in Saccharomyces cerevisiae reveals a novel G1/M checkpoint. Mol. Cell. Biol. 15: 5312-5321.
59. Uhlmann, F. and K. Nasmyth. 1998. Cohesion between sister chromatids must be established during DNA replication. Curr. Biol. 8: 1095-1101.
60. Weinert, T.A. and L.H. Hartwell. 1988. The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae. Science 241: 317-322.
61. _. 1990. Characterization of RAD9 of Saccharomyces cerevisiae and evidence that its function acts posttranslationally in cell cycle arrest after DNA damage. Mol. Cell Biol. 10: 6554-6564.
62. Weinert, T.A., G.L. Riser, and L.H. Hartwell. 1994. Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair. Genes & Dev. 8: 652-665.
63. Wells, W.A. and A.W. Murray. 1996. Aberrantly segregating centromeres activate the spindle assembly checkpoint in budding yeast. J. Cell Biol. 133: 75-84.
64. Yamamoto, A., V. Guacci, and D. Koshland. 1996a. Pds1p is required for faithful execution of anaphase in the yeast, Saccharomyces cerevisiae. J. Cell Biol. 133: 85-97.
65. _. 1996b. Pds1p, an inhibitor of anaphase in budding yeast, plays a critical role in the APC and checkpoint pathway(s). J. Cell Biol. 133: 99-110.