The RHC21 gene of budding yeast, a homologue of the fission yeast rad21+ gene, is essential for chromosome segregation

Molecular and General Genetics

Volumn 257, Issue 2, 1998, Pages 149-156

  Heo, S J ^a   Tatebayashi, K ^a   Kato, J ^a   Ikeda, H ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Chromosome segregation; Nocodazole; Saccharomyces cerevisiae

Indexed keywords

CELL NUCLEUS DNA; NOCODAZOLE;

ARTICLE; CELL GROWTH; CELL STRUCTURE; CELL VIABILITY; CHROMOSOME SEGREGATION; CONTROLLED STUDY; DNA REPLICATION; FLOW CYTOMETRY; GAMMA RADIATION; GENE DISRUPTION; GENE FUNCTION; GENE ISOLATION; GENE MUTATION; MICROTUBULE; MINICHROMOSOME; NONHUMAN; PRIORITY JOURNAL; RADIATION INJURY; SACCHAROMYCES CEREVISIAE; TEMPERATURE SENSITIVE MUTANT; ULTRAVIOLET RADIATION; YEAST;

CELL CYCLE PROTEINS; CELL NUCLEUS; CHROMOSOMES, FUNGAL; DNA REPLICATION; DNA, FUNGAL; FUNGAL PROTEINS; GAMMA RAYS; GENES, FUNGAL; MICROTUBULES; MITOSIS; MITOTIC SPINDLE APPARATUS; NOCODAZOLE; NUCLEAR PROTEINS; PHOSPHOPROTEINS; RADIATION TOLERANCE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE PROTEINS; TEMPERATURE;

FUNGI; MYXOGASTRIA; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES POMBE; SACCHAROMYCETALES; SCHIZOSACCHAROMYCES POMBE;

EID: 0031885741     PISSN: 00268925     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004380050634     Document Type: Article

References (36)

1. Basrai MA, Kingsbury J, Koshland D, Spencer F, Hieter P (1996) Faithful chromosome transmission requires Spt4p. a putative regulator of chromatin structure in Saccharomyces cerevisiae. Mol Cell Biol 16:2838-2847
2. Birkenhihl RP, Subramani S (1992) Cloning and characterization of rad21, an essential gene of Schizosaccharomyces pombe involved in DNA double-strand-break repair. Nucleic Acids Res 20:6605-6611
3. Birkenbihl RP, Subramani S (1995) The rad21 gene product of Schizosaccharomyces pombe is a nuclear, cell cycle-regulated phosphoprotein. J Biol Chem 270:7703-7711
4. Boeke JD, Trueheart J, Natsoulis G, Fink GR (1987) 5-Fluoroorotic acid as a selective agent in yeast molecular genetics. Methods Enzymol 154:164-175
5. Cohen-Fix O, Peters JM, Kirschner MW, Koshland D (1996) Anaphase initiation in Saccharomycex cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p. Genes Dev 24:3081-3093
6. Connelly C, Mieter P (1996) Budding yeast SKP1 encodes an evolutionary conserved kinetochore protein required for cell cycle progression. Cell 86:275-285
7. Friedberg EC, Siede W, Cooper AJ (1991) The Molecular and cellular biology of the yeast Saccharomyces. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, pp 407-521
8. Goh PY, Kilmartin JV (1993) NDC10: a gene involved in chromosome segregation in Saccharomyces cerevisiae. J Cell Biol 121:503-512
9. Glotzer M, Murray AW, Kirschner MW (1991) Cyclin is degraded by the ubiquitin pathway. Nature 349:132-138
10. Hartwell LH, Smith D (1985) Altered fidelity of mitotic chromosome transmission in cell cycle mutants of S. cerevisiae. Genetics 110:381-395
11. Heichman KA, Roberts JM (1996) The yeast CDC16 and CDC27 genes restrict DNA replication to once per cell cycle. Cell 84: 39-48
12. Holm C, Stearns T, Bolstein D (1989) DNA topoisomerase II must act at mitosis to prevent nondisjunction and chromosome breakage. Mol Cell Biol 9:159-168
13. Hoyt MA, Stearns T, Bolstein D (1990) Chromosome instability mutants of Saccharomyces cerevisiae that are detective in microtubule-mediated processes. Mol Cell Biol 10:223-234
14. Hoyt MA, Totis L, Roberts BT (1991) S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function. Cell 66:507-517
15. Hutter KJ, Eipel HE (1979) Microbial determinations by flow cytometry. J Gen Microbiol 113:369-375
16. Juang YL, Huang J, Peters JM, McLaughlin ME, Tai CY, Pellman D (1997) APC-mediated proteolysis of Ase1 and morphogenesis of the mitotic spindle. Science 275:1311-1314
17. Kilmartin J, Adams A (1984) Structural rearrangements of tubulin and actin during the cell cycle of the yeast Saccharomyces. J Cell Biol 98:922-933
18. Lechner J (1994) A zinc finger protein, essential for chromosome segregation, constitutes a putative DNA binding subunit of the Saccharomyces cerevisiae kinetochore complex, Cbf3. EMBO J 13:5203-5211
19. Mark DR, Winston F, Hieter P (1990) Laboratory course manual for methods in yeast genetics. Cold Spring Harbor Laboratory Press, Cold Spring Harbor. New York
20. Mckay MJ, Troelstra C, van der Spek P, Kanaar R, Smit B, Hagemeijer A, Bootsma D. Hoeijmakers JH (1996) Sequence conservation of the rad21 Schizosaccharomyces pombe DNA double-strand break repair gene in human and mouse. Genomics 36:305-315
21. Palmer RE, Hogan E. Koshland D (1990) Mitotic transmission of artificial chromosomes in cdc mutants of the yeast Saccharomyces cerevisiae. Genetics 125:763-774
22. Pringle JR, Preston RA, Adams EM, Stearns T, Drubin DG, Haarer BK. Jones LW (1989) Fluorescence microscopy methods for yeast. Methods Cell Biol 31:357-435
23. Rong L, Murray AW (1991) Feedback control of mitosis in budding yeast. Cell 66:519-531
24. Rothstein RJ (1983) One-step gene disruption in yeast. Methods Enzymol 101:202-211
25. Ruggieri R, Tanaka K, Nakafuku M, Kaziro Y, Toh-e A, Matsumoto K (1989) MSI1, a negative regulator of the RAS-cAMP pathway in Saccharomyces cerevisiae. Proc Natl Acad Sci USA 86:8778-8782
26. Schatz PJ, Solomon F, Bolstein D (1988) Isolation and characterization of conditional-lethal mutations in the TUBI alpha-tubulin gene of the yeast Saccharomyces cerevisiae. Genetics 120:681-695
27. Southern EM (1975) Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol 98:503-517
28. Stoler S, Keith KC, Curnick KE, Fitzgerald-Hayes M (1995) A mutation in CSE4, an essential gene encoding a novel chromatin-associated protein in yeast, causes chromosome nondisjunction and cell cycle arrest at mitosis. Genes Dev 9:573-586
29. Strunnikov AV, Hogan E, Koshland D (1995) SMC2, a Saccharomyces cerevisiae gene essential for chromosome segregation and condensation, defines a subgroup within the SMC family. Genes Dev 9:587-599
30. Strunnikov AV, Larionov VL, Koshland D (1993) SMC1: an essential yeast gene encoding a putative head-rod-tail protein is required for nuclear division and defines a new ubiquitous protein family. J Cell Biol 123:1635-1648
31. Tsukamoto Y, Kato J, Ikeda H (1996) Effects of mutations of RAD50, RAD51, RAD52, and related genes on illegitimate recombination in Saccharomyces cerevisiae. Genetics 142:383-391
32. Weinert TA, Hartwell LH (1988) The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces. cerevisiae. Science 241:317-322
33. Weinert TA, Kiser GL, Hartwell LH (1994) Mitotic Checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair. Genes Dev 8:652-665
34. Wilson R et al. (1994) 2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans. Nature 368:32-38
35. Yamamoto A, Guacci V, Koshland D (1996a) Pds1p is required for faithful execution of anaphase in the yeast Saccharomyces cerevisiae. J Cell Biol 133:85-97
36. Yamamoto A, Guacci V, Koshland D (1996b) Pds1p, an inhibitor of anaphase in budding yeast, plays a critical role in the APC and checkpoint pathway(s). J Cell Biol 133:99-110