Clamping down on clamps and clamp loaders - The eukaryotic replication factor C

European Journal of Biochemistry

Volumn 254, Issue 2, 1998, Pages 209-216

  Mossi, Romina ^a   Hübscher, Ulrich ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Apoptosis; Clamp; Clamp loader; Differentiation; DNA polymerase ; Eukaryotic DNA replication; Proliferating cell nuclear antigen; Replication factor C; S phase checkpoint regulation; Telomere

Indexed keywords

CYCLINE;

DNA REPAIR; DNA REPLICATION; DNA SYNTHESIS; EUKARYOTE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; SHORT SURVEY; TELOMERE;

EUKARYOTA;

EID: 0032102260     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1998.2540209.x     Document Type: Short Survey

References (63)

1. Kelman, Z. & O'Donnell, M. (1995) DNA polymerase III holoenzyme: structure and function of a chromosomal replicating machine, Annu. Rev. Biochem. 64, 171-200.
2. Studwell-Vaughan, P. S. & O'Donnell, M. (1991) Constitution of the twin polymerase of DNA polymerase III holoenzyme, J. Biol. Chem. 266, 19833-19841.
3. Yuzhakov, A., Turner, J. & O'Donnell, M. (1996) Replisome assembly reveals the basis for asymmetric function in leading and lagging strand replication, Cell 86, 877-886.
4. Cullmann, G., Fien, K., Kobayashi, R. & Stillman, B. (1995) Characterization of the five replication factor C genes of Saccharomyces cerevisiae, Mol. Cell. Biol. 15, 4661-4671.
5. Kelman, Z. & O'Donnell, M. (1995) Structural and functional similarities of prokaryotic and eukaryotic DNA polymerase sliding clamps, Nucleic Acids Res. 23, 3613-3620.
6. Kuriyan, J. & O'Donnell, M. (1993) Sliding clamps of DNA polymerases, J. Mol. Biol. 234, 915-925.
7. Yao, N., Turner, J., Kelman, Z., Stukenberg, P. T., Dean, F., Shechter, D., Pan, Z. Q., Hurwitz, J. & O'Donnell, M. (1996) Clamp loading, unloading and intrinsic stability of the PCNA, beta and gp45 sliding clamps of human, E. coli and T4 replicases, Genes Cells 1, 101-113.
8. Stukenberg, P. T., Turner, J. & O'Donnell, M. (1994) An explanation for lagging strand replication: polymerase hopping among DNA sliding clamps, Cell 78, 877-887.
9. Naktinis, V., Onrust, R., Fang, L. & O'Donnell, M. (1995) Assembly of a chromosomal replication machine: two DNA polymerases, a clamp loader, and sliding clamps in one holoenzyme particle. II. Intermediate complex between the clamp loader and its clamp, J. Biol. Chem. 270, 13358-133565.
10. Mossi, R., Jónsson, Z. O., Allen, B. L., Hardin, S. H. & Hübscher, U. (1997) Replication factor C interacts with the C-terminal side of proliferating cell nuclear antigen, J. Biol. Chem. 272, 1769-1776.
11. Tsurimoto, T. & Stillman, B. (1989) Multiple replication factors augment DNA synthesis by the two eukaryotic DNA polymerases, alpha and delta, EMBO J. 8, 3883-3889.
12. Lee, S. H., Kwong, A. D., Pan, Z. Q. & Hurwitz, J. (1991) Studies on the activator 1 protein complex, an accessory factor for proliferating cell nuclear antigen-dependent DNA polymerase delta, J. Biol. Chem. 266, 594-602.
13. Yoder, B. L. & Burgers, P. M. (1991) S. cerevisiae replication factor C. I. Purification and characterization of its ATPase activity, J. Biol. Chem. 266, 22689-22697.
14. Fien, K. & Stillman, B. (1992) Identification of replication factor C from Saccharomyces cerevisiae: a component of the leading-strand DNA replication complex, Mol. Cell. Biol. 12, 155-163.
15. Podust, V. N., Georgaki, A., Strack, B. & Hübscher, U. (1992) Calf thymus RF-C as an essential component for DNA polymerase delta and epsilon holoenzymes function, Nucleic Acids Res. 20, 4159-4165.
16. Chen, M., Pan, Z. Q. & Hurwitz, J. (1992) Studies of the cloned 37-kDa subunit of activator 1 (replication factor C) of HeLa cells, Proc. Natl Acad. Sci. USA 89, 5211-5215.
17. Chen, M., Pan, Z. Q. & Hurwitz, J. (1992) Sequence and expression in Escherichia coli of the 40-kDa subunit of activator 1 (replication factor C) of HeLa cells, Proc. Natl Acad. Sci. USA 89, 2516-2520.
18. Burbelo, P. D., Utani, A., Pan, Z. Q. & Yamada, Y. (1993) Cloning of the large subunit of activator 1 (replication factor C) reveals homology with bacterial DNA ligases, Proc. Natl Acad. Sci. USA 90, 11543-11547.
19. Bunz, F., Kobayashi, R. & Stillman, B. (1993) cDNAs encoding the large subunit of human replication factor C, Proc. Natl Acad. Sci. USA 90, 11014-11018.
20. Burgers, P. M. (1991) Saccharomyces cerevisiae replication factor C. II. Formation and activity of complexes with the proliferating cell nuclear antigen and with DNA polymerases delta and epsilon, J. Biol. Chem. 266, 22698-22706.
21. Li, X. & Burgers, P. M. (1994) Molecular cloning and expression of the Saccharomyces cerevisiae RFC3 gene, an essential component of replication factor C, Proc. Natl Acad. Sci. USA 91, 868-872.
22. Li, X. & Burgers, P. M. (1994) Cloning and characterization of the essential Saccharomyces cerevisiae RFC4 gene encoding the 37-kDa subunit of replication factor C, J. Biol. Chem. 269, 21880-21884.
23. Gary, S. L. & Burgers, M. J. (1995) Identification of the fifth subunit of Saccharomyces cerevisiae replication factor C, Nucleic Acids Res. 23, 4986-4991.
24. Noskov, V., Maki, S., Kawasaki, Y., Leem, S. H., Ono, B., Araki, H., Pavlov, Y. & Sugino, A. (1994) The RFC2 gene encoding a subunit of replication factor C of Saccharomyces cerevisiae, Nucleic Acids Res. 22, 1527-1535.
25. Bult, C. J., White, O., Olsen, G. J., Zhou, L., Fleischmann, R. D., Sutton, G. G., Blake, J. A., FitzGerald, L. M., Clayton, R. A., Gocayne, J. D., Kerlavage, A. R., Dougherty, B. A., Tomb, J. F., Adams, M. D., Reich, C. I., Overbeek, R., Kirkness, E. F., Weinstock, K. G., Merrick, J. M., Glodek, A., Scott, J. L., Geoghagen, N. S. M. & Venter, J. C. (1996) Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii, Science 273, 1058-1073.
26. Podust, V. N. & Hübscher, U. (1993) Lagging strand DNA synthesis by calf thymus DNA polymerases alpha, beta, delta and epsilon in the presence of auxiliary proteins, Nucleic Acids Res. 21, 841-846.
27. Tsurimoto, T. & Stillman, B. (1990) Functions of replication factor C and proliferating-cell nuclear antigen: functional similarity of DNA polymerase accessory proteins from human cells and bacteriophage T4, Proc. Natl Acad. Sci. USA 87, 1023-1027.
28. Tsurimoto, T. & Stillman, B. (1991) Replication factors required for SV40 DNA replication in vitro. I. DNA structure-specific recognition of a primer-template junction by eukaryotic DNA polymerases and their accessory proteins, J. Biol. Chem. 266, 1950-1960.
29. Podust, L. M., Podust, V. N., Sogo, J. M. & Hübscher, U. (1995) Mammalian DNA polymerase auxiliary proteins: analysis of replication factor C-catalyzed proliferating cell nuclear antigen loading onto circular double-stranded DNA, Mol. Cell. Biol. 15, 3072-3081.
30. Tinker, R. L., Kassavetis, G. A. & Geiduschek, E. P. (1994) Detecting the ability of viral, bacterial and eukaryotic replication proteins to track along DNA, EMBO J. 13, 5330-5337.
31. Fotedar, R., Mossi, R., Fitzgerald, P., Rousselle, T., Maga, G., Brickner, H., Messier, H., Kasibhatla, S., Hübscher, U. & Fotedar, A. (1996) A conserved domain of the large subunit of replication factor C binds PCNA and acts like a dominant negative inhibitor of DNA replication in mammalian cells, EMBO J. 15, 4423-4433.
32. Lu, Y., Zeft, A. S. & Riegel, A. T. (1993) Cloning and expression of a novel human DNA binding protein, PO-GA, Biochem. Biophys. Res. Commun. 193, 779-786.
33. Podust, L. M., Podust, V. N., Floth, C. & Hübscher, U. (1994) Assembly of DNA polymerase delta and epsilon holoenzymes depends on the geometry of the DNA template, Nucleic Acids Res. 22, 2970-2975.
34. Uhlmann, F., Cai, J., Gibbs, E., O'Donnell, M. & Hurwitz, J. (1997) Deletion analysis of the large subunit p140 in human replication factor C reveals regions required for complex formation and replication activities, J. Biol. Chem. 272, 10058-10064.
35. Bork, P., Hofmann, K., Bucher, P., Neuwald, A. F., Altschul, S. F. & Koonin, E. V. (1997) A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins, FASEB J. 11, 68-76.
36. Uhlmann, F., Cai, J., Flores-Rozas, H., Dean, F. B., Finkelstein, J., O'Donnell, M. & Hurwitz, J. (1996) In vitro reconstitution of human replication factor C from its five subunits, Proc. Natl Acad. Sci. USA 93, 6521-6526.
37. Podust, V. N. & Fanning, E. (1997) Assembly of functional replication factor C expressed using recombinant baculoviruses, J. Biol. Chem. 272, 6303-6310.
38. Cai, J., Uhlmann, F., Gibbs, E., Flores-Rozas, H., Lee, C. G., Phillips, B., Finkelstein, J., Yao, N., O'Donnell, M. & Hurwitz, J. (1996) Reconstitution of human replication factor C from its five subunits in baculovirus-infected insect cells, Proc. Natl Acad. Sci. USA 93, 12896-12901.
39. Cai, J., Gibbs, E., Uhlmann, F., Phillips, B., Yao, N., O'Donnell, M. & Hurwitz, J. (1997) A complex consisting of human replication factor C p40, p37, and p36 subunits is a DNA-dependent ATPase and an intermediate in the assembly of the holoenzyme, J. Biol. Chem. 272, 18974-18981.
40. Uhlmann, F., Gibbs, E., Cai, J., O'Donnell, M. & Hurwitz, J. (1997) Identification of regions within the four small subunits of human replication factor C required for complex formation and DNA replication, J. Biol. Chem. 272, 10065-10071.
41. Halligan, B. D., Teng, M., Guilliams, T. G., Nauert, J. B. & Halligan, N. L. (1995) Cloning of the murine cDNA encoding VDJP, a protein homologous to the large subunit of replication factor C and bacterial DNA ligases, Gene (Amst.) 161, 217-222.
42. Lu, Y. & Riegel, A. T. (1994) The human DNA-binding protein, PO-GA, is homologous to the large subunit of mouse replication factor C: regulation by alternate 3′ processing of mRNA, Gene (Amst.) 145, 261-265.
43. Howell, E. A., McAlear, M. A., Rose, D. & Holm, C. (1994) CDC44: a putative nucleotide-binding protein required for cell cycle progression that has homology to subunits of replication factor C, Mol. Cell. Biol. 14, 255-267.
44. McAlear, M. A., Howell, E. A., Espenshade, K. K. & Holm, C. (1994) Proliferating cell nuclear antigen (po130) mutations suppress cdc44 mutations and identify potential regions of interaction between the two encoded proteins, Mol. Cell. Biol. 14, 4390-4397.
45. McAlear, M. A., Tuffo, K. M. & Holm, C. (1996) The large subunit of replication factor C (Rfc1p/Cdc44p) is required for DNA replication and DNA repair in Saccharomyces cerevisiae, Genetics 142, 65-78.
46. Aboussekhra, A., Biggerstaff, M., Shivji, M. K., Vilpo, J. A., Moncollin, V., Podust, V. N., Protic, M., Hübscher, U., Egly, J. M. & Wood, R. D. (1995) Mammalian DNA nucleotide excision repair reconstituted with purified protein components, Cell 80, 859-868.
47. Shivji, M. K., Podust, V. N., Hübscher, U. & Wood, R. D. (1995) Nucleotide excision repair DNA synthesis by DNA polymerase epsilon in the presence of PCNA, RFC, and RPA, Biochemistry 34, 5011-5017.
48. Griffiths, D. J., Barbet, N. C., McCready, S., Lehmann, A. R. & Carr, A. M. (1995) Fission yeast rad17: a homologue of budding yeast RAD24 that shares regions of sequence similarity with DNA polymerase accessory proteins, EMBO J. 14, 5812-5823.
49. Luckow, B., Bunz, F., Stillman, B., Lichter, P. & Schulz, G. (1994) Cloning, expression, and chromosomal localization of the 140-kilodalton subunit of replication factor C from mice and humans, Mol. Cell. Biol. 14, 1626-1634.
50. Jaharul Haque, S., van der Kuip, H., Kumar, A., Aulitzky, W. E., Rutherford, M. N., Huber, C., Fischer, T. & Williams, B. R. (1996) Overexpression of mouse p140 subunit of replication factor C accelerates cellular proliferation, Cell Growth Differ. 7, 319-326.
51. Maga, G., Mossi, R., Fischer, R., Berchtold, M. W. & Hübscher, U. (1997) Phosphorylation of the PCNA binding domain of the large subunit of replication factor C by Ca2+/calmodulin-dependent protein kinase II inhibits DNA synthesis, Biochemistry 36, 5300-5310.
52. Song, Q., Lu, H., Zhang, N., Luckow, B., Shah, G., Poirier, G. & Lavin, M. (1997) Specific cleavage of the large subunit of replication factor C in apoptosis is mediated by CPP32-like protease, Biochem. Biophys. Res. Commun. 233, 343-348.
53. Rhéaume, E., Cohen, L. Y., Uhlmann, F., Lazure, C., Alam, A., Hurwitz, J., Sékaly, R. P. & Denis, F. (1997) The large subunit of replication factor C is a substrate for caspase-3 in vitro and is cleaved by caspase-3-like protease during Fas-mediated apoptosis, EMBO J. 16, 6346-6354.
54. Adams, A. K. & Holm, C. (1996) Specific DNA replication mutations affect telomere length in Saccharomyces cerevisiae, Mol. Cell. Biol. 16, 4614-4620.
55. Uchiumi, F., Ohta, T. & Tanuma, S. (1996) Replication factor C recognizes 5′-phosphate ends of telomeres, Biochem. Biophys. Res. Commun. 229, 310-315.
56. Lyle, R. E., Habener, J. F. & McGehee, R. E. Jr (1996) Antisense oligonucleotides to differentiation-specific element binding protein (DSEB) mRNA inhibit adipocyte differentiation, Biochem. Biophys. Res. Commun. 228, 709-715.
57. Okumura, K., Nogami, M., Taguchi, H., Dean, F. B., Chen, M., Pan, Z. Q., Hurwitz, J., Shiratori, A., Murakami, Y., Ozawa, K. & Eki, T. (1995) Assignment of the 36.5-kDa (RFCS), 37-kDa (RFC4), 38-kDa (RFC3), and 40-kDa (RFC2) subunit genes of human replication factor C to chromosome bands 12q24.2-q24.3, 3q27, 13q12.3-q13, and 7q11.23, Genomics 25, 274-278.
58. Pan, Z. Q., Chen, M. & Hurwitz, J. (1993) The subunits of activator 1 (replication factor C) carry out multiple functions essential for proliferating-cell nuclear antigen-dependent DNA synthesis, Proc. Natl Acad. Sci. USA 90, 6-10.
59. Osborne, L. R., Martindale, D., Scherer, S. W., Shi, X. M., Huizenga, J., Heng, H. H. Q., Costa, T. Pober, B., Lew, L., Brinkman, J., Rommens, J., Koop, B. & Tsui, L. C. (1996) Identification of genes from a 500-kb region at 7q11.23 that is commonly deleted in Williams syndrome patients, Genomics 36, 328-336.
60. Peoples, R., Perez-Jurado, L., Wang, Y. K., Kaplan, P. & Francke, U. (1996) The gene for replication factor C subunit 2 (RFC2) is within the 7q11.23 Williams syndrome deletion, Am. J. Hum. Genet. 58, 1370-1373.
61. Sugimoto, K., Shimomura, T., Hashimoto, K., Araki, H., Sugino, A. & Matsumoto, K. (1996) Rfc5, a small subunit of replication factor C complex, couples DNA replication and mitosis in budding yeast, Proc. Natl Acad. Sci. USA 93, 7048-7052.
62. Sugimoto, K., Ando, S., Shimomura, T. & Matsumoto, K. (1997) Rfc5, a replication factor C component, is required for regulation of Rad53 protein kinase in the yeast checkpoint pathway, Mol. Cell. Biol. 17, 5905-5914.
63. Zuo, S., Gibbs, E., Kelman Z., Wang, T. S.-F., O'Donnell, M. MacNeill, S. A. & Hurwitz, J. (1997) DNA polymerase delta isolated from Schizosaccharomyces pombe contains five subunits, Proc. Natl Acad. Sci. USA 94, 11244-11249.