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Volumn 2, Issue 1, 2001, Pages 1-16

Multiple oxidants in cytochrome P450 catalyzed reactions: Implications for drug metabolism

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; HEME; IRON; NITRIC OXIDE SYNTHASE; OXIDIZING AGENT; OXYGEN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

EID: 0035031013     PISSN: 13892002     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389200013338847     Document Type: Article
Times cited : (14)

References (114)
  • 2
    • 0034000027 scopus 로고    scopus 로고
    • Cytochrome P450 enzymes in aquatic invertebrates: Recent advances and future directions
    • (2000) Aquat. Toxicol. , vol.48 , Issue.4 , pp. 529-547
    • Snyder, M.J.1
  • 10
    • 85037409652 scopus 로고    scopus 로고
    • Cytochrome P450 CYP2D6. IARC Sci. Publ., 148(Metabolic Polymorphisms and Susceptibility to Cancer)
    • (1999) , pp. 209-229
    • Wolf, C.R.1    Smith, G.2
  • 16
    • 0034106141 scopus 로고    scopus 로고
    • Pharmacogenomics of cytochrome P450 and other enzymes involved in biotransformation of xenobiotics
    • (2000) Drug Dev. Res. , vol.49 , Issue.1 , pp. 4-16
    • Guengerich, F.P.1
  • 17
    • 0034189835 scopus 로고    scopus 로고
    • Cytochrome P450-mediated cardiovascular drug interactions
    • (2000) Heart Dis. , vol.2 , Issue.3 , pp. 254-258
    • Cheng, J.W.M.1
  • 18
    • 0032733974 scopus 로고    scopus 로고
    • Prediction of human clearance of twenty-nine drugs from hepatic microsomal intrinsic clearance data: An examination of in vitro half-life approach and nonspecific binding to microsomes
    • (1999) Drug Metab. Dispos. , vol.27 , Issue.11 , pp. 1350-1359
    • Obach, R.S.1
  • 20
    • 0032777032 scopus 로고    scopus 로고
    • The metabolism of antihistamines and drug interactions: The role of cytochrome P450 enzymes
    • (1999) Clin. Exp. Allergy , vol.29 , Issue.SUPPL. 3 , pp. 116-124
    • Renwick, A.G.1
  • 23
    • 17144448816 scopus 로고
    • Cytochromes P450 and formation of reactive metabolites. Role in drug-induced hepatotoxicity
    • (1993) Therapie , vol.48 , Issue.6 , pp. 537-548
    • Pessayre, D.1
  • 24
    • 85037402483 scopus 로고    scopus 로고
    • Cytochrome P450 in the metabolism of xenobiotics and drug-drug interactions. Department of Clinical Pharmacokinetics, Janssen Research Foundation, Beerse, Belg. Pharmacochem. Libr., 28(XIVth International Chemistry, 1996)
    • (1997) , pp. 219-230
    • Van't, K.G.1    Lavrijsen, K.2
  • 25
    • 0033086126 scopus 로고    scopus 로고
    • Mechanisms and significance of inhibitory drug interactions involving cytochrome P450 enzymes (review). School of Physiology and Pharmacology, University of New South Wales, Sydney, Australia
    • (1999) Int. J. Mol. Med. , vol.3 , Issue.3 , pp. 227-238
    • Murray, M.1
  • 26
    • 85037406376 scopus 로고    scopus 로고
    • th International Symposium on Microsomes and Drug Oxidations, Montpellier, France, Abstract #
    • (1998) , pp. 410
    • Vaz, A.D.N.1    Coon, M.J.2
  • 27
    • 0022878676 scopus 로고
    • Characterization of a catalytically self-sufficient 119,000-dalton cytochrome P-450 monooxygenase induced by barbiturates in Bacillus megaterium
    • CODEN: JBCHA3 ISSN:0021-9258.
    • (1986) J. Biol. Chem. , vol.261 , Issue.16 , pp. 7160-7169
    • Narhi, L.O.1    Fulco, A.J.2
  • 35
    • 0030701529 scopus 로고    scopus 로고
    • Oxidation kinetics of ethanol by human cytochrome P450 2E1. Rate-limiting product release accounts for effects of isotopic hydrogen substitution and cytochrome b5 on steady-state kinetics
    • (1997) J. Biol. Chem. , vol.272 , Issue.47 , pp. 29643-29651
    • Bell, L.C.1    Guengerich, F.P.2
  • 36
    • 0019877830 scopus 로고
    • On the mechanism of action of cytochrome P-450. Evaluation of homolytic and heterolytic mechanisms of oxygen-oxygen bond cleavage during substrate hydroxylation by peroxides
    • (1981) J. Biol. Chem. , vol.256 , Issue.23 , pp. 12127-12133
    • Blake II, R.C.1    Coon, M.J.2
  • 37
    • 0024506371 scopus 로고
    • On the mechanism of action of cytochrome P-450. Spectral intermediates in the reaction with iodosobenzene and its derivatives
    • (1989) J. Biol. Chem. , vol.264 , Issue.7 , pp. 3694-3701
    • Blake II, R.C.1    Coon, M.J.2
  • 41
    • 0005085193 scopus 로고
    • Oxo- and peroxo-transition metal species in chemical and biochemical oxidations. Possible models for the oxygen activation and transfer catalyzed by cytochrome P-450
    • [Proc. Symp.] Meeting Date 1978
    • (1979) Biochem. Clin. Aspects Oxygen , pp. 277-309
    • Groves, J.T.1    McClusky, G.A.2
  • 47
    • 0022364867 scopus 로고
    • Preparation and properties of ferrous chloroperoxidase complexes with dioxygen, nitric oxide, and an alkyl isocyanide. Spectroscopic dissimilarities between the oxygenated forms of chloroperoxidase and cytochrome P-450
    • (1985) J. Biol. Chem. , vol.260 , Issue.29 , pp. 15530-15535
    • Sono, M.1    Eble, K.S.2    Dawson, J.H.3    Hager, L.P.4
  • 48
    • 0005024664 scopus 로고    scopus 로고
    • Cytochrome P450 Structure, Science Mechanism, and Biochemistry by Paul R. Ortiz De Montellano. (Washington, D. C.)
    • (1996) , vol.271 , Issue.5255 , pp. 1507-1508
    • Dawson, J.1
  • 49
    • 0019321015 scopus 로고
    • On the mechanism of action of cytochrome P-450. Spectral intermediates in the reaction of P-450LM2 with peroxy compounds
    • (1980) J. Biol. Chem. , vol.255 , Issue.9 , pp. 4100-4111
    • Blake II, R.C.1    Coon, M.J.2
  • 55
    • 0344724192 scopus 로고
    • Aromatization of tetralone derivatives by 5,10,15,20-tetrakis(pentafluorophenyl)porphyrinatoiron(III) chloride/iodosobenzene and cytochrome P-450cam: A model study on aromatase cytochrome P-450 reaction
    • (1989) J. Am. Chem. Soc. , vol.111 , Issue.1 , pp. 410-411
    • Watanabe, Y.1    Ishimura, Y.2
  • 56
    • 0024424975 scopus 로고
    • A model study on aromatase cytochrome P-450 reaction: Transformation of androstene-3,17,19-trione to 10β-hydroxyester-4-ene-3,17-dione
    • (1989) J. Am. Chem. Soc. , vol.111 , Issue.20 , pp. 8047-8049
    • Watanabe, Y.1    Ishimura, Y.2
  • 59
    • 0019978673 scopus 로고
    • A new hypothesis based on suicide substrate inhibitor studies for the mechanism of action of aromatase
    • (1982) Cancer Res. , vol.42 , Issue.SUPPL. 8 , pp. 3327-3333
    • Covey, D.F.1    Hood, W.F.2
  • 60
    • 0020324229 scopus 로고
    • Biochemical mechanism of aromatization
    • (1982) Cancer Res. , vol.42 , Issue.SUPPL. 8 , pp. 3277-3280
    • Fishman, J.1
  • 61
    • 0019827338 scopus 로고
    • Mechanism of estrogen biosynthesis. Participation of multiple enzyme sites in placental aromatase hydroxylations
    • (1981) J. Biol. Chem. , vol.256 , Issue.9 , pp. 4466-4471
    • Fishman, J.1    Goto, J.2
  • 68
  • 76
    • 0028821761 scopus 로고
    • On the mechanism of nitric oxide formation upon oxidative cleavage of C = N(OH) bonds by NO-synthases and cytochromes P450
    • (1995) Biochimie , vol.77 , Issue.7-8 , pp. 661-667
    • Mansuy, D.1    Boucher, J.L.2    Clement, B.3
  • 81
    • 0002148690 scopus 로고    scopus 로고
    • Active iron-oxo and iron-peroxo species in cytochromes P450 and peroxidases; oxo-hydroxo tautomerism with water-soluble metalloporphyrins
    • (Berlin), (Metal-Oxo and Metal-Peroxo Species in Catalytic Oxidations)
    • (2000) Struct. Bonding , vol.97 , pp. 1-35
    • Meunier, B.1    Bernadou, J.2
  • 86
    • 0028181731 scopus 로고
    • Glu318 and Thr319 mutations of cytochrome P450 1A2 remarkably enhance homolytic O-O cleavage of alkyl hydroperoxides. An optical absorption spectral study
    • (1994) J. Biol. Chem. , vol.269 , Issue.18 , pp. 13296-13304
    • Shimizu, T.1    Murakami, Y.2    Hatano, M.3
  • 90
    • 0024974060 scopus 로고
    • Crystal structure of the carbon monoxide-substrate-cytochrome P-450CAM ternary complex
    • (1989) Biochemistry , vol.28 , Issue.19 , pp. 7586-7592
    • Raag, R.1    Poulos, T.L.2
  • 95
    • 0000767074 scopus 로고    scopus 로고
    • Role of the Heme Active Site and Protein Environment in Structure, Spectra, and Function of the Cytochrome P450s
    • (Washington, D. C.)
    • (2000) Chem. Rev. , vol.100 , Issue.2 , pp. 407-419
    • Loew, G.H.1    Harris, D.L.2
  • 102
    • 0034233377 scopus 로고    scopus 로고
    • First success of catalytic epoxidation of olefins by an electron-rich iron(III) porphyrin complex and H202: Imidazole effect on the activation of H202 by iron porphyrin complexes in aprotic solvent
    • (2000) J. Inorg. Biochem. , vol.80 , Issue.3-4 , pp. 219-225
    • Nam, W.1    Lee, H.J.2    Oh, S.-Y.3    Kim, C.4    Jang, H.G.5
  • 104
    • 0034672754 scopus 로고    scopus 로고
    • Porphyrin-Fe(III)-hydroperoxide and porphyrin-Fe(III)-peroxide anion as catalytic intermediates in cytochrome P450-catalyzed hydroxylation reactions: A molecular orbital study
    • (2000) Biophys. Chem. , vol.88 , Issue.1-3 , pp. 11-34
    • Zakharieva, O.1    Trautwein, A.X.2    Veeger, C.3
  • 105
    • 0028352457 scopus 로고
    • Application of chemical cytochrome P450 model systems to studies on drug metabolism. VII. Novel metabolic pathway of arylethers by cytochrome P450: Cleavage of the oxygen-aromatic ring bond accompanying atom of the active species in cytochrome P450 models and cytochrome P450
    • (1994) Arch. Biochem. Biophys. , vol.310 , Issue.2 , pp. 402-409
    • Ohe, T.1    Mashino, T.2    Hirobe, M.3
  • 110
    • 0005068414 scopus 로고
    • Superoxide-ion oxidation of hydrophenazines, reduced flavins, hydroxylamine, and related substrates via hydrogen-atom transfer
    • (1980) J. Am. Chem. Soc. , vol.102 , Issue.25 , pp. 7591-7593
    • Nanni E.J., Jr.1    Sawyer, D.T.2


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