메뉴 건너뛰기




Volumn 7, Issue 3, 2001, Pages 405-420

X-ray crystallographic observation of "in-line" and "adjacent" conformations in a bulged self-cleaving RNA/DNA hybrid

Author keywords

DNA; Hydrogen bonding; Nucleotide bulge; Phosphoryl transfer; Ribozyme; RNA; X ray crystallography

Indexed keywords

DNA HYBRID; METAL ION; OXYGEN; PHOSPHATE; RIBONUCLEOTIDE; RIBOZYME; RNA;

EID: 0035028049     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1355838201001935     Document Type: Article
Times cited : (21)

References (82)
  • 2
    • 0026019625 scopus 로고
    • Structural basis for the 3′-5′ exonuclease activity of Escherichia coli DNA polymerase I: A two metal ion mechanism
    • (1991) EMBO J , vol.10 , pp. 25-33
    • Beese, L.S.1    Steitz, T.A.2
  • 5
    • 0026597444 scopus 로고
    • Free R value: A novel statistical quantity for assessing the accuracy of crystal structures
    • (1992) Nature , vol.355 , pp. 472-475
    • Brünger, A.T.1
  • 9
    • 0023364038 scopus 로고
    • The chemistry of self-splicing RNA and RNA enzymes
    • (1987) Science , vol.236 , pp. 1532-1539
    • Cech, T.R.1
  • 11
    • 0025645986 scopus 로고
    • Characterization of deoxy- and ribo-containing oligonucleotide substrates in the hammerhead selfcleavage reaction
    • (1990) Biochimie , vol.72 , pp. 819-823
    • Dahm, S.C.1    Uhlenbeck, O.C.2
  • 14
  • 15
    • 84950262770 scopus 로고
    • Structural patterns in nucleic acids
    • Bürgi H-B, Dunitz JD, eds. New York: VCH Publishers Inc.
    • (1994) Structure correlation , vol.2 , pp. 705-749
    • Egli, M.1
  • 18
    • 0034708334 scopus 로고    scopus 로고
    • Structure and function of the hairpin ribozyme
    • (2000) J Mol Biol , vol.297 , pp. 269-291
    • Fedor, M.J.1
  • 20
    • 0002455712 scopus 로고
    • Mechanistic principles of enzyme-catalyzed cleavage of phosphodiester bonds
    • Linn SM, Lloyd RS, Roberts RJ, eds., Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press
    • (1993) Nucleases, 2nd Ed. , pp. 1-34
    • Gerit, J.A.1
  • 24
    • 0031194873 scopus 로고    scopus 로고
    • A unique mechanism for RNA catalysis: The role of metal cofactors in hairpin ribozyme cleavage
    • (1997) Chem Biol , vol.4 , pp. 513-517
    • Hampel, A.1    Cowan, J.A.2
  • 37
    • 0029981788 scopus 로고    scopus 로고
    • Ribozyme-mediated cleavage of a substrate analogue containing an internucleotide-bridging 5′-phosphorothioate: Evidence for the single-metal model
    • (1996) Biochemistry , vol.35 , pp. 5308-5317
    • Kuimelis, R.G.1    McLaughlin, L.W.2
  • 40
    • 0034639428 scopus 로고    scopus 로고
    • a of the 2′-hydroxyl group of a phosphorylated ribose: Implications for the mechanism of hammerhead ribozyme catalysis
    • (2000) J Am Chem Soc , vol.122 , pp. 166-167
    • Lyne, P.D.1    Karplus, M.2
  • 42
    • 0029949701 scopus 로고    scopus 로고
    • Structure and function of the hammerhead ribozyme: An unfinished story
    • (1996) RNA , vol.2 , pp. 395-403
    • McKay, D.B.1
  • 45
    • 84920325457 scopus 로고
    • AMoRe: An automated package for molecular replacement
    • (1994) Acta Cryst A , vol.50 , pp. 157-163
    • Navaza, J.1
  • 56
    • 0029168512 scopus 로고
    • Kinetic evidence based on solvent isotope effects for the nonexistence of a proton-transfer process in reactions catalyzed by a hammerhead ribozyme: Implication to a double-metal-ion mechanism of catalysis
    • (1995) J Am Chem Soc , vol.117 , pp. 2357-2358
    • Sawata, S.1    Komiyama, M.2    Taira, K.3
  • 58
    • 0029073091 scopus 로고
    • The crystal structure of an all-RNA hammerhead ribozyme: A proposed mechanism for RNA catalytic cleavage
    • (1995) Cell , vol.81 , pp. 991-1002
    • Scott, W.G.1    Finch, J.T.2    Klug, A.3
  • 61
    • 0026102040 scopus 로고
    • Configurationally defined phosphorothioate-containing oligonucleotides in the study of the mechanism of cleavage of hammerhead ribozymes
    • (1991) Nucleic Acids Res , vol.19 , pp. 1183-1188
    • Slim, G.1    Gait, M.J.2
  • 63
    • 0032831634 scopus 로고    scopus 로고
    • Relationship between internucleotide linkage geometry and the stability of RNA
    • (1999) RNA , vol.5 , pp. 1308-1325
    • Soukup, G.A.1    Breaker, R.R.2
  • 78
  • 81
    • 0033835214 scopus 로고    scopus 로고
    • Two crystal forms of helix II of Xenopus laevis 5S rRNA with a cytosine bulge
    • (2000) RNA , vol.6 , pp. 1316-1324
    • Xiong, Y.1    Sundaralingam, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.