A two-metal ion mechanism operates in the hammerhead ribozyme-mediated cleavage of an RNA substrate

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 2, 1998, Pages 542-547

  Lott, William B ^a   Pontius, Brian W ^a,b   Von Hippel, Peter H ^a  

^a UNIVERSITY OF OREGON   (United States)

^b NONE   (United States)

Author keywords

Lanthanum ion; Magnesium ion; Metal ion activation; Ribozyme function; RNA cleavage

Indexed keywords

LANTHANUM; MAGNESIUM ION; METAL ION; RIBOZYME; RNA;

ARTICLE; BINDING SITE; CATALYSIS; DISSOCIATION CONSTANT; ENZYME BINDING; ENZYME MECHANISM; ENZYME SUBSTRATE; PRIORITY JOURNAL; RNA CLEAVAGE;

BINDING SITES; METALS; RNA; RNA, CATALYTIC; SUBSTRATE SPECIFICITY;

EID: 0031882388     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.2.542     Document Type: Article

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