Adaptation of tick-borne encephalitis virus to BHK-21 cells results in the formation of multiple heparan sulfate binding sites in the envelope protein and attenuation in vivo

Journal of Virology

Volumn 75, Issue 12, 2001, Pages 5627-5637

  Mandl, Christian W ^a   Kroschewski, Helga ^a   Allison, Steven L ^a   Kofler, Regina ^a   Holzmann, Heidemarie ^a   Meixner, Tamara ^a   Heinz, Franz X ^a  

^a UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ENVELOPE PROTEIN; GLYCOPROTEIN E; HEPARAN SULFATE;

ADAPTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; ENCEPHALITIS VIRUS; FLAVIVIRUS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE; VIRUS MUTATION; VIRUS PLAQUE; VIRUS RECOMBINANT;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; BINDING SITES; CELL LINE; DISEASE MODELS, ANIMAL; ENCEPHALITIS VIRUSES, TICK-BORNE; ENCEPHALITIS, TICK-BORNE; HEPARITIN SULFATE; MICE; MODELS, MOLECULAR; MUTATION; PLAQUE ASSAY; VIRAL ENVELOPE PROTEINS; VIRULENCE;

EID: 0035024156     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.12.5627-5637.2001     Document Type: Article

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