Characterization of a Chinese hamster ovary cell line developed by retroviral insertional mutagenesis that is resistant to Sindbis virus infection

Journal of Virology

Volumn 73, Issue 6, 1999, Pages 4919-4924

  Jan, Jia Tsrong ^a,b   Byrnes, Andrew P ^a   Griffin, Diane E ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CHONDROITIN SULFATE; GLYCOSAMINOGLYCAN; HEPARAN SULFATE; NEOMYCIN; VIRUS GLYCOPROTEIN;

ANIMAL CELL; ANTIBIOTIC RESISTANCE; ARTHRITIS; ARTICLE; CHO CELL; ISOTOPE LABELING; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; RETROVIRUS; SINDBIS VIRUS; VIRUS CELL INTERACTION; VIRUS INFECTION; VIRUS REPLICATION;

EID: 0033033071     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.73.6.4919-4924.1999     Document Type: Article

References (44)

1. Albritton, L. M., L. Tseng, D. T. Scadden, and J. M. Cunningham. 1989. A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection. Cell 57:659-666.
2. Banfield, B. W., Y. Leduc, L. Esford, K. Schubert, and F. Tufaro. 1995. Sequential isolation of proteoglycan synthesis mutants by using herpes simplex virus as a selective agent: evidence for a proteoglycan-independent virus entry pathway. J. Virol. 69:3290-3298.
3. Barklis, E., R. C. Mulligan, and R. Jaenisch. 1986. Chromosomal position or virus mutation permits retrovirus expression in embryonal carcinoma cells. Cell 47:391-399.
4. Burge, B., and E. Pfefferkorn. 1966. Isolation and characterization of conditional lethal mutants of Sindbis virus. Virology 30:204-213.
5. Byrnes, A. P., and D. E. Griffin. 1998. Binding of Sindbis virus to cell surface heparan sulfate. J. Virol. 72:7349-7356.
6. Chang, W., C. Hubbard, C. Friedel, and H. E. Ruley. 1993. Enrichment of insertional mutants following retrovirus gene trap selection. Virology 193: 737-747.
7. Esko, J. D. 1993. Preparation and analysis of glycoconjugates, p. 1721-1729. In Current protocols in molecular biology. Wiley, New York, N.Y.
8. Feng, Y., C. C. Broder, P. E. Kennedy, and E. A. Berger. 1996. HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science 272:872-876.
9. Frankel, W., T. A. Potter, N. Rosenberg, J. Lenz, and T. V. Rajan. 1995. Retroviral insertional mutagenesis of a target allele in a heterozygous murine cell line. Proc. Natl. Acad. Sci. USA 82:6600-6604.
10. Greve, J. M., C. P. Forte, C. W. Marlor, A. M. Meyer, H. Hoover-Litty, D. Wunderlich, and A. McClelland. 1991. Mechanisms of receptor-mediated rhinovirus neutralization defined by two soluble forms of ICAM-1. J. Virol. 65:6015-6023.
11. Griffin, D. E., and J. M. Hardwick. 1997. Regulators of apoptosis on the road to persistent alphavirus infection. Annu. Rev. Microbiol. 51:565-592.
12. Griffin, D. E., and R. T. Johnson. 1977. Role of the immune response in recovery from Sindbis virus encephalitis in mice. J. Immunol. 118:1070-1075.
13. Gruenheid, S., L. Gatzke, H. Meadows, and F. Tufaro. 1993. Herpes simplex virus infection and propagation in a mouse L cell mutant lacking heparan sulfate proteoglycans. J. Virol. 67:93-100.
14. Gupta, R. S., D. Y. Chan, and L. Siminovitch. 1978. Evidence for functional hemizygosity at the Emtr locus in CHO cells through segregation analysis. Cell 14:1007-1013.
15. Gupta, R. S., D. Y. Chan, and L. Siminovitch. 1978. Evidence for variation in the number of functional gene copies at the AmaR locus in Chinese hamster cell lines. J. Cell. Physiol. 97:461-467.
16. Hubbard, S. C., L. Walls, H. E. Ruley, and E. A. Muchmore. 1994. Generation of Chinese hamster ovary cell glycosylation mutants by retroviral insertional mutagenesis. J. Biol. Chem. 269:3717-3724.
17. Inocencio, N. M., J. M. Moehring, and T. J. Moehring. 1993. A mutant CHO-K1 strain with resistance to Pseudomonas exotoxin A is unable to process the precursor fusion glycoprotein of Newcastle disease virus. J. Virol. 67:593-595.
18. Jackson, A. C., T. R. Moench, and D. E. Griffin. 1987. The pathogenesis of spinal cord involvement in the encephalomyelitis of mice caused by neuroadapted Sindbis virus infection. Lab. Investig. 56:418-423.
19. Jackson, A. C., T. R. Moench, B. D. Trapp, and D. E. Griffin. 1988. Basis of neurovirulence in Sindbis virus encephalomyelitis of mice. Lab. Investig. 58:503-509.
20. Jaenisch, R., D. Jahner, P. Nobis, I. Simon, J. Lohler, K. Harbers, and D. Grotkopp. 1981. Chromosomal position and activation of retroviral genomes inserted into the germ line of mice. Cell 24:519-529.
21. King, W., M. D. Patel, L. I. Lobel, S. P. Goff, and M. C. Nguyen-Huu. 1985. Insertion mutagenesis of embryonal carcinoma cells by retroviruses. Science 228:554-558.
22. Klimstra, W. B., K. D. Ryman, and R. E. Johnston. 1998. Adaptation of Sindbis virus to BHK cells selects for use of heparan sulfate as an attachment receptor. J. Virol. 72:7357-7366.
23. Levine, B., Q. Huang, J. T. Isaacs, J. C. Reed, D. E. Griffin, and J. M. Hardwick. 1993. Conversion of lytic to persistent alphavirus infection by the bcl-2 cellular oncogene. Nature 361:739-742.
24. Lewis, J., S. L. Wesselingh, D. E. Griffin, and J. M. Hardwick. 1996. Alpha-virus-induced apoptosis in mouse brains correlates with neurovirulence. J. Virol. 70:1828-1835.
25. Lustig, S., A. C. Jackson, C. S. Hahn, D. E. Griffin, E. G. Strauss, and J. H. Strauss. 1988. The molecular basis of Sindbis virus neurovirulence in mice. J. Virol. 62:2329-2336.
26. Maassen, J. A., and C. Terhorst. 1981. Identification of a cell-surface protein involved in the binding site of Sindbis virus on human lymphoblastoic cell lines using a heterobifunctional cross-linker. Eur. J. Biochem. 115:153-158.
27. Mento, S. J., and L. Siminovitch. 1981. Isolation and preliminary characterization of Sindbis virus-resistant Chinese hamster ovary cells. Virology 111: 320-330.
28. Moehring, J. M., and T. J. Moehring. 1983. Strains of CHO-Kl cells resistant to Pseudomonas exotoxin A and cross-resistant to diphtheria toxin and viruses. Infect. Immun. 41:998-1009.
29. Montgomery, R. I., M. S. Warner, B. J. Lum, and P. G. Spear. 1996. Herpes simplex virus-1 entry into cells mediated by a novel member of the TNF/ NGF receptor family. Cell 87:427-436.
30. Niklasson, B., A. Espmark, J. W. LeDuc, T. P. Gargan, W. A. Ennis, R. B. Tesh, and A. J. Main, Jr. 1984, Association of a Sindbis-like virus with Ockelbo disease in Sweden. Am. J. Trop. Med. Hyg. 33:1212-1217.
31. Reddy, S., J. V. DeGregori, H. von Melchner, and H. E. Ruley. 1991. Retrovirus promoter-trap vector to induce lacZ gene fusions in mammalian cells. J. Virol. 65:1507-1515.
32. Shieh, M. T., D. WuDunn, R. I. Montgomery, J. D. Esko, and P. G. Spear. 1992. Cell surface receptors for herpes simplex virus are heparan sulfate proteoglycans. J. Cell Biol. 116:1273-1281.
33. Smith, A. L., and G. H. Tignor. 1980. Host receptors for two strains of Sindbis virus. Arch. Virol. 66:11-26.
34. Sorge, J., A. E. Cutting, V. D. Erdman, and J. W. Gautsch. 1984. Integration-specific retrovirus expression in embryonal carcinoma cells. Proc. Natl. Acad. Sci. USA 81:6627-6631.
35. Stanley, P., and W. Chaney. 1985. Control of carbohydrate processing: the leclA CHO mutation results in partial loss of N-acetylglucosaminyltransferase I activity. Mol. Cell. Biol. 5:1204-1211.
36. Strauss, J. H., and E. G. Strauss. 1994. The alphaviruses: gene expression, replication, and evolution. Microbiol. Rev. 58:491-562.
37. Terry-Allison, T., R. I. Montgomery, J. C. Whitbeck, R. Xu, G. H. Cohen, and R J. Eisenberg. 1998. HveA (herpesvirus entry mediator A), a coreceptor for herpes simplex virus entry, also participates in virus-induced cell fusion. J. Virol. 72:5802-5810.
38. Tucker, P. C., and D. E. Griffin. 1991. The mechanism of altered Sindbis virus neurovirulence associated with a single amino acid change in the E2 glycoprotein. J. Virol. 65:1551-1557.
39. Tucker, P. C., S. H. Lee, N. Bui, D. Martinie, and D. E. Griffin. 1997. Amino acid changes in the Sindbis virus E2 glycoprotein that increase neurovirulence improve entry into neuroblastoma cells. J. Virol. 71:6106-6112.
40. Tufaro, F., M. D. Snider, and S. L. McKnight. 1987. Identification and characterization of a mouse cell mutant defective in the intracellular transport of glycoproteins. J. Cell Biol. 105:647-657.
41. Ubol, S., and D. E. Griffin. 1991. Identification of a putative alphavirus receptor on mouse neural cells. J. Virol. 65:6913-6921.
42. von Melchner, H., and H. E. Ruley. 1989. Identification of cellular promoters by using a retrovirus promoter trap. J. Virol. 63:3227-3233.
43. Wang, K.-S., R. J. Kuhn, E. G. Strauss, S. Ou, and J. H. Strauss. 1992. High-affinity laminin receptor is a receptor for Sindbis virus in mammalian cells. J. Virol. 66:4992-5001.
44. Watson, D. G., J. M. Moehring, and T. J. Moehring. 1991. A mutant CHO-K1 strain with resistance to Pseudomonas exotoxin A and alphaviruses fails to cleave Sindbis virus gycoprotein PE2. J. Virol. 65:2332-2339.