Release of urokinase plasminogen activator receptor during urosepsis and endotoxemia

Kidney International

Volumn 59, Issue 6, 2001, Pages 2054-2061

  Florquin, Sandrine ^a,b   Van den Berg, José G ^a,b   Olszyna, Dariusz P ^a,b   Claessen, Nike ^a,b   Opal, Steven M ^a,b   Weening, Jan J ^a,b   Van der Poll, Tom ^a,b  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b BROWN UNIVERSITY   (United States)

Author keywords

Anti inflammatory response; Bacterial infection; CD87; Cytokines; Nephrotoxicity; Tubular epithelial cells; Urinary tract infection

Indexed keywords

ESCHERICHIA COLI ENDOTOXIN; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; UROKINASE RECEPTOR;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOTOXEMIA; ESCHERICHIA COLI; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KIDNEY BIOPSY; KIDNEY FUNCTION; PRIORITY JOURNAL; PYELONEPHRITIS; SEPSIS; URINARY TRACT INFECTION;

EID: 0035018480     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2001.0590062054.x     Document Type: Article

References (52)

1. Kao JS, Stucker DM, Warren JW, Mobley HL: Pathogenicity island sequences of pyelonephritogenic Escherichia coli CFT073 are associated with virulent uropathogenic strains. Infect Immunol 65:2812-2820, 1997
2. Hedges S, Anderson P, Lidin-Janson G, et al: Interleukin-6 response to deliberate colonization of the human urinary tract with gram-negative bacteria. Infect Immunol 59:421-427, 1991
3. Agace WW, Hedges SR, Ceska M, Svanborg C: Interleukin-8 and the neutrophil response to mucosal gram-negative infection. J Clin Invest 92:780-785, 1993
4. Prins JM, Van Agtmael MA, Kuijper EJ, et al: Antibiotic-induced endotoxin release in patients with gram-negative urosepsis: A double-blind study comparing imipenem and ceftazidime. J Infect Dis 172:886-891, 1995
5. Olszyna DP, Prins JM, Dekkers PE, et al: Sequential measurements of chemokines in urosepsis and experimental endotoxemia. J Clin Immunol 19:399-405, 1999
6. Olszyna DP, Prins JM, Buis B, et al: Levels of inhibitors of tumor necrosis factor alpha and interleukin 1beta in urine and sera of patients with urosepsis. Infect Immunol 66:3527-3534, 1998
7. Kirchheimer JC, Nong YH, Remold HG: IFN-gamma, tumor necrosis factor-alpha, and urokinase regulate the expression of urokinase receptors on human monocytes. J Immunol 141:4229-234, 1988
8. Picone R, Kajtaniak EL, Nielsen LS, et al: Regulation of urokinase receptors in monocytelike U937 cells by phorbol ester phorbol myristate acetate. J Cell Biol 108:693-702, 1989
9. Gyetko MR, Sitrin RG, Fuller JA, et al: Function of the urokinase receptor (CD87) in neutrophil chemotaxis. J Leukoc Biol 58:533-538, 1995
10. Nykjaer A, Moller B, Todd RF III, et al: Urokinase receptor: An activation antigen in human T lymphocytes. J Immunol 152:505-516, 1994
11. Mignatti P, Mazzieri R, Rifkin DB: Expression of the urokinase receptor in vascular endothelial cells is stimulated by basic fibroblast growth factor. J Cell Biol 113:1193-1201, 1991
12. Reuning U, Little SP, Dixon EP, Bang NU: Effect of thrombin, the thrombin receptor activation peptide, and other mitogens on vascular smooth muscle cell urokinase receptor mRNA levels. Blood 84:3700-3708, 1994
13. Wagner SN, Atkinson MJ, Wagner C, et al: Sites of urokinase-type plasminogen activator expression and distribution of its receptor in the normal human kidney. Histochem Cell Biol 105:53-60, 1996
14. Simon DI, Rao NK, Xu H, et al: Mac-1 (CD11b/CD18) and the urokinase receptor (CD87) form a functional unit on monocytic cells. Blood 88:3185-3194, 1996
15. Petty HR, Todd RF III: Receptor-receptor interactions of complement receptor type 3 in neutrophil membranes. J Leukoc Biol 54:492-494, 1993
16. Blasi F: uPA, uPAR, PAI-1: Key intersection of proteolytic, adhesive and chemotactic highways? Immunol Today 18:415-417, 1997
17. Gyetko MR, Sud S, Kendall T, et al: Urokinase receptor-deficient mice have impaired neutrophil recruitment in response to pulmonary pseudomonas aeruginosa infection. J Immunol 165:1513-1519, 2000
18. Wei Y, Waltz DA, Rao N, et al: Identification of the urokinase receptor as an adhesion receptor for vitronectin. J Biol Chem 269:32380-32388, 1994
19. Xue W, Kindzelskii AL, Todd RF III, Petty HR: Physical association of complement receptor type 3 and urokinase-type plasminogen activator receptor in neutrophil membranes. J Immunol 152:4630-4640, 1994
20. Wei Y, Lukashev M, Simon DI, et al: Regulation of integrin function by the urokinase receptor. Science 273:1551-1555, 1996
21. Wei Y, Yang X, Liu Q, et al: A role for caveolin and the urokinase receptor in integrin-mediated adhesion and signaling. J Cell Biol 144:1285-1294, 1999
22. Sappino AP, Huarte J, Vassalli JD, Belin D: Sites of synthesis of urokinase and tissue-type plasminogen activators in the murine kidney. J Clin Invest 87:962-970, 1991
23. Keeton M, Ahn C. Eguchi Y, et al: Expression of type 1 plasminogen activator inhibitor in renal tissue in murine lupus nephritis. Kidney Int 47:148-157, 1995
24. Troyer DA, Chandrasekar B, Thinnes T, et al: Effects of energy intake on type 1 plasminogen activator inhibitor levels in glomeruli of lupus-prone B/W mice. Am J Pathol 146:111-120, 1995
25. Yamamoto K, Loskutoff DJ: The kidneys of mice with autoimmune disease acquire a hypofibrinolytic/procoagulant state that correlates with the development of glomerulonephritis and tissue microthrombosis. Am J Pathol 151:725-734, 1997
26. Kitching AR, Holdsworth SR, Ploplis VA, et al: Plasminogen and plasminogen activators protect against renal injury in crescentic glomerulonephritis. J Exp Med 185:963-968, 1997
27. Olszyna DP, Opal SM, Prins JM, et al: Chemotactic activity of CXC chemokines interleukin (1L)-8, growth-related oncogene (GRO) alpha and epithelial cell-derived neutrophil-activating protein (ENA)-78 in urine of patients with urosepsis. J Infect Dis 182:1731-1737, 2000
28. Dekkers PE, Ten Hove T, Te Velde AA, et al: Upregulation of monocyte urokinase plasminogen activator receptor during human endotoxemia. Infect Immunol 68:2156-2160, 2000
29. Mizukami IF, Faulkner NE, Gyetko MR, et al: Enzyme-linked immunoabsorbent assay detection of a soluble form of urokinase plasminogen activator receptor in vivo. Blood 86:203-211, 1995
30. Ninomiya H, Hasegawa Y, Nagasawa T, Abe T: Excess soluble urokinase-type plasminogen activator receptor in the plasma of patients with paroxysmal nocturnal hemoglobinuria inhibits cell-associated fibrinolytic activity. Int J Hematol 65:285-291, 1997
31. Pedersen N, Schmitt M, Ronne E, et al: A ligand-free, soluble urokinase receptor is present in the ascitic fluid from patients with ovarian cancer. J Clin Invest 92:2160-2167, 1993
32. Stephens RW, Pedersen AN, Nielsen HJ, et al: ELISA determination of soluble urokinase receptor in blood from healthy donors and cancer patients. Clin Chem 43:1868-1876, 1997
33. Rubin-Kelley VE, Jevnikar AM: Antigen presentation by renal tubular epithelial cells. J Am Soc Nephrol 2:13-26, 1991
34. Yard BA, Daha MR, Kooymans-Couthino M, et al: IL-1 alpha stimulated TNF alpha production by cultured human proximal tubular epithelial cells. Kidney Int 42:383-389, 1992
35. Boswell RN, Yard BA, Schrama E, et al: Interleukin 6 production by human proximal tubular epithelial cells in vitro: Analysis of the effects of interleukin-1 alpha (IL-1 alpha) and other cytokines. Nephrol Dial Transplant 9:599-606, 1994
36. Schmouder RL, Strieter RM, Wiggins RC, et al: In vitro and in vivo interleukin-8 production in human renal cortical epithelia. Kidney Int 41:191-198, 1992
37. Schmouder RL, Strieter RM, Kunkel SL: Interferon-gamma regulation of human renal cortical epithelial cell-derived monocyte chemotactic peptide-1. Kidney Int 44:43-49, 1993
38. Schmouder RL, Streiter RM, Walz A, Kunkel SL: Epithelial-derived neutrophil-activating factor-78 production in human renal tubule epithelial cells and in renal allograft rejection. Transplantation 59:118-124, 1995
39. Gerritsma JS, Hiemstra PS, Gerritsen AF, et al: Regulation and production of IL-8 by human proximal tubular epithelial cells in vitro. Clin Exp Immunol 103:289-294, 1996
40. Kruger S, Brandt E, Klinger M, Kreft B: Interleukin-8 secretion of cortical tubular epithelial cells is directed to the basolateral environment and is not enhanced by apical exposure to Escherichia coli. Infect Immunol 68:328-334, 2000
41. Brooimans RA, Stegmann AP, Van Dorp WT, et al: Interleukin 2 mediates stimulation of complement C3 biosynthesis in human proximal tubular epithelial cells. J Clin Invest 88:379-384, 1991
42. Van Kooten C, Van Der Linde X, Woltman AM, et al: Synergistic effect of interleukin-1 and CD40L on the activation of human renal tubular epithelial cells. Kidney Int 56:41-51, 1999
43. El Awad B, Kreft B, Wolber EM, et al: Hormones-cytokines-signaling: Hypoxia and interleukin-1beta stimulate vascular endothelial growth factor production in human proximal tubular cells. Kidney Int 58:43-50, 2000
44. Chavakis T, Kanse SM, Yutzy B, et al: Vitronectin concentrates proteolytic activity on the cell surface and extracellular matrix by trapping soluble urokinase receptor-urokinase complexes. Blood 91:2305-2312, 1998
45. Estreicher A, Muhlhauser J, Carpentier JL, et al: The receptor for urokinase type plasminogen activator polarizes expression of the protease to the leading edge of migrating monocytes and promotes degradation of enzyme inhibitor complexes. J Cell Biol 111:783-792, 1990
46. Rao NK, Shi GP, Chapman HA: Urokinase receptor is a multifunctional protein: Influence of receptor occupancy on macrophage gene expression. J Clin Invest 96:465-474, 1995
47. Sitrin RG, Todd RF III, Albrecht E, Gyetko MR: The urokinase receptor (CD87) facilitates CD11b/CD18-mediated adhesion of human monocytes. J Clin Invest 97:1942-1951, 1996
48. May AE, Kanse SM, Lund LR, et al: Urokinase receptor (CD87) regulates leukocyte recruitment via beta 2 integrins in vivo. J Exp Med 188:1029-1037, 1998
49. Eitzman DT, McCoy RD, Zheng X, et al: Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-1 gene. J Clin Invest 97:232-237, 1996
50. Eddy AA: Molecular insights into renal interstitial fibrosis. (editorial) J Am Soc Nephrol 7:2495-2508, 1996
51. Eddy AA: Interstitial fibrosis in hypercholesterolemic rats: Role of oxidation, matrix synthesis, and proteolytic cascades. Kidney Int 53:1182-1189, 1998
52. Baricos WH, Cortez SL, Deboisblanc M, Xin S: Transforming growth factor-beta is a potent inhibitor of extracellular matrix degradation by cultured human mesangial cells. J Am Soc Nephrol 10:790-795, 1999