Hypoxia and interleukin-1β stimulate vascular endothelial growth factor production in human proximal tubular cells

Kidney International

Volumn 58, Issue 1, 2000, Pages 43-50

  Awad, Baha El ^a   Kreft, Burkhard ^a   Wolber, Eva Maria ^a   Hellwig Bürgel, Thomas ^a   Metzen, Eric ^a   Fandrey, Joachim ^a   Jelkmann, Wolfgang ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

Author keywords

Cytokines; Inflammation; Microvascular leakage; Renal tubules; Tumor necrosis factor

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1; INTERLEUKIN 1BETA; MESSENGER RNA; VASCULOTROPIN; CARCINOGEN; DNA BINDING PROTEIN; ENDOTHELIAL CELL GROWTH FACTOR; HIF1A PROTEIN, HUMAN; HIF1A PROTEIN, MOUSE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 1; LYMPHOKINE; NUCLEAR PROTEIN; OXYGEN; PHORBOL 13 ACETATE 12 MYRISTATE; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN A;

ANGIOGENESIS; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HYPOXIA; KIDNEY PROXIMAL TUBULE; NEPHRITIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN INDUCTION; ANIMAL; ANOXIA; CELL CULTURE; CHEMISTRY; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION; GENETICS; LIVER CELL CARCINOMA; METABOLISM; MOUSE; PATHOPHYSIOLOGY; PHYSIOLOGY; WESTERN BLOTTING;

ANIMALS; ANOXIA; BLOTTING, WESTERN; CARCINOGENS; CARCINOMA, HEPATOCELLULAR; DNA-BINDING PROTEINS; ENDOTHELIAL GROWTH FACTORS; GENE EXPRESSION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTERLEUKIN-1; KIDNEY TUBULES, PROXIMAL; LYMPHOKINES; MICE; NUCLEAR PROTEINS; OXYGEN; RNA, MESSENGER; TETRADECANOYLPHORBOL ACETATE; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0033623788     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2000.00139.x     Document Type: Article

References (42)

1. 1. YARD BA, DAHA MR, KOOYMANS-COUTHINO M, BRUIJN JA, PAAPE MA, SCHRAMA E, VAN ES LA, VAN DER WOUDE FJ: IL-α stimulated TNF-α production by cultured human proximal tubular epithelial cells. Kidney Int 42:383-389, 1992
2. 2. DECKERS JGM, VAN DER WOUDE FJ, VAN DER KOOIJ SW, DAHA MR: Synergistic effect of IL-1α, IFN-γ, and TNF-α in RANTES production by human renal tubular epithelial cells in vitro. J Am Soc Nephrol 9:194-202, 1998
3. 3. HUGHES AK, STRICKLETT PK, KOHAN DE: Shiga toxin-1 regulation of cytokine production by human proximal tubule cells. Kidney Int 54:1093-1106, 1998
4. 4. GRÖNE H-J, SIMON M, GRÖNE EF: Expression of vascular endothelial growth factor in renal vascular disease and renal allografts. J Pathol 177:259-267, 1995
5. 5. FERRARA N, DAVIS-SMYTH T: The biology of vascular endothelial growth factor. Endocr Rev 18:4-25, 1997
6. 6. WHITE FC, CARROLL SM, KAMPS MP: VEGF mRNA is reversibly stabilized by hypoxia and persistently stabilized in VEGF-overexpressing human tumor cell lines. Growth Factors 12:289-301, 1995
7. 7. LEVY AP, LEVY NS, GOLDBERG MA: Post-transcriptional regulation of vascular endothelial growth factor by hypoxia. J Biol Chem 271:2746-2753, 1996
8. 8. LIU Y, COX SR, MORITA T, KOUREMBANAS S: Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells. Circ Res 77:638-643, 1995
9. 9. FORSYTHE JA, JIANG B-H, IYER NV, AGANI F, LEUNG SW, KOOS RD, SEMENZA GL: Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol Cell Biol 16:4604-4613, 1996
10. 10. HUANG E, ARANY Z, LIVINGSTON DM, BUNN HF: Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its a subunit. J Biol Chem 271:32253-32259, 1996
11. 11. SALCEDA S, CARO J: Hypoxia-inducible factor 1α (HIF-1α) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. J Biol Chem 272:22642-22647, 1997
12. 12. HELLWIG-BÜRGEL T, RUTKOWSKI K, METZEN E, FANDREY J, JELKMANN W: Interleukin-1β and tumor necrosis factor-α stimulate DNA-binding of hypoxia-inducible factor-1. Blood 94:1561-1567, 1999
13. 13. DETRISAC CJ, SENS MA, GARVIN AJ, SPICER SS, SENS DA: Tissue culture of human kidney epithelial cells of proximal tubule origin. Kidney Int 25:383-390, 1984
14. 14. KREFT B, BRZOSKA S, DOEHN C, DAHA MR, VAN DER WOUDE FJ, SACK K: 1,25-Dihydroxycholecalciferol enhances the expression of MHC class II antigens and intercellular adhesion molecule-1 by human renal tubular epithelial cells. J Urol 155:1448-1453, 1996
15. 15. LEEKER A, KREFT B, SANDMANN J, BATES J, WASENAUER G, MÜLLER H, SACK K, KUMAR S: Tamm-Horsfall protein inhibits binding of S-and P-fimbriated Escherichia coli to human renal tubular epithelial cells. Exp Nephrol 5:38-46, 1997
16. 16. KRÜGER S, KLINIKER M, KRÜGER S, BRANDT E, KREFT B: Interleukin-8 secretion of cortical tubular epithelial cells is directed to the basolateral environment and is not enhanced by apical exposure to Escherichia coli. Infect Immun 68:328-334, 2000
17. 17. HEITS F, KATSCHINSKI DM, WIEDEMANN GJ, WEISS C, JELKMANN W: Serum vascular endothelial growth factor (VEGF), a prognostic indicator in sarcoma and carcinoma patients. Int J Oncol 10:333-337, 1997
18. 18. CHOMCZYNSKI P, SACCHI N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159, 1987
19. 19. GASSMANN M, FANDREY J, BICHET S, WARTENBERG M, MARTI HH, BAUER C, WENGER RH, ACKER H: Oxygen supply and oxygen-dependent gene expression in differentiating embryonic stem cells. Proc Natl Acad Sci USA 93:2867-2872, 1996
20. 20. FANDREY J, BUNN HF: In vivo and in vitro regulation of erythropoietin mRNA: Measurement by competitive polymerase chain reaction. Blood 81:617-623, 1993
21. 2 in erythropoietin-producing human hepatoma cell cultures. Am J Physiol 265:C1266-C1270, 1993
22. 22. SEMENZA GL, WANG GL: A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol Cell Biol 12:5447-5454, 1992
23. 23. ROLFS A, KVIETIKOVA I, GASSMANN M, WENGER RH: Oxygen-regulated transferrin expression is mediated by hypoxia-inducible factor-1. J Biol Chem 272:20055-20062, 1997
24. 24. BERSE B, BROWN LF, VAN DE WATER L, DVORAK HF, SENGER DR: Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors. Mol Biol Cell 3:211-220, 1992
25. 25. BROWN LF, BERSE B, TOGNAZZI K, MANSEAU EJ, VAN DE WATER L, SENGER DR, DVORAK HF, ROSEN S: Vascular permeability factor mRNA and protein expression in human kidney. Kidney Int 42:1457-1461, 1992
26. 26. KITAMOTO Y, TOKUNAGA H, TOMITA K: Vascular endothelial growth factor is an essential molecule for mouse kidney development: Glomerulogenesis and nephrogenesis. J Clin Invest 99:2351-2357, 1997
27. 27. SIMON M, GRÖNE H-J, JÖHREN O, KULLMER J, PLATE KH, RISAU W, FUCHS E: Expression of vascular endothelial growth factor and its receptors in human renal ontogenesis and in adult kidney. Am J Physiol 268:F240-F250, 1995
28. 28. KLANKE B, SIMON M, RÖCKL W, WEICH HA, STOLTE H, GRÖNE H-J: Effects of vascular endothelial growth factor (VEGF)/vascular permeability factor (VPF) on haemodynamics and permselectivity of the isolated perfused rat kidney. Nephrol Dial Transplant 13:875-885, 1998
29. 29. WEBB NJA, WATSON CJ, ROBERTS ISD, BOTTOMLEY MJ, JONES CA, LEWIS MA, POSTLETHWAITE RJ, BRENCHLEY PEC: Circulating vascular endothelial growth factor is not increased during relapses of steroid-sensitive nephrotic syndrome. Kidney Int 55:1063-1071, 1999
30. 30. GOLDBERG MA, SCHNEIDER TJ: Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin. J Biol Chem 269:4355-4359, 1994
31. 31. MARTI HH, RISAU W: Systemic hypoxia changes the organ-specific distribution of vascular endothelial growth factor and its receptors. Proc Natl Acad Sci USA 95:15809-15814, 1998
32. 32. SANDNER P, GESS B, WOLF K, KURTZ A: Divergent regulation of vascular endothelial growth factor and of erythropoietin gene expression in vivo. Eur J Physiol 431:905-912, 1996
33. 33. LI J, PERRELLA MA, TSAI J-C, YET S-F, HSIEH C-M, YOSHIZUMI M, PATTERSON C, ENDEGE WO, ZHOU F, LEE M-E: Induction of vascular endothelial growth factor gene expression by interleukin-1β in rat aortic smooth muscle cells. J Biol Chem 270:308-312, 1995
34. 34. BEN-AV P, CROFFORD LJ, WILDER RL HLA T: Induction of vascular endothelial growth factor expression in synovial fibroblasts by prostaglandin E and interleukin-1: A potential mechanism for inflammatory angiogenesis. FEBS Lett 372:83-87, 1995
35. 35. JACKSON JR, MINTON JAL, HO ML, WEI N, WINKLER JD: Expression of vascular endothelial growth factor in synovial fibroblasts is induced by hypoxia and interleukin 1β. J Rheumatol 24:1253-1259, 1997
36. 36. FRANK S, HÜBNER G, BREIER G, LONGAKER MT, GREENHALGH DG, WERNER S: Regulation of vascular endothelial growth factor expression in cultured keratinocytes. J Biol Chem 270:12607-12613, 1995
37. 37. RYUTO M, ONO M, IZUMI H, YOSHIDA S, WEICH HA, KOHNO K, KUWANO M: Induction of vascular endothelial growth factor by tumor necrosis factor α in human glioma cells. J Biol Chem 271:28220-28228, 1996
38. 38. AKAGI Y, LUI W, XIE K, ZEBROWSKI B, SHAHEEN RM, ELLIS LM: Regulation of vascular endothelial growth factor expression in human colon cancer by interleukin-1β. Br J Cancer 80:1506-1511, 1999
39. 39. COHEN T, NAHARI D, CEREM LW, NEUFELD G, LEVI B-Z: Interleukin 6 induces the expression of vascular endothelial growth factor. J Biol Chem 271:736-741, 1996
40. 40. WANG GL, SEMENZA GL: Oxygen sensing and response to hypoxia by mammalian cells. Redox Rep 2:89-96, 1996
41. 41. GASSMANN M, WENGER RH: HIF-1, a mediator of the molecular response to hypoxia. News Physiol Sci 12:214-218, 1997
42. 42. GLEADLE JM, RATCLIFFE PJ: Hypoxia and the regulation of gene expression. Mol Med Today 4:122-129, 1998