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Volumn 65, Issue 3, 1997, Pages 285-291

Excess soluble urokinase-type plasminogen activator receptor in the plasma of patients with paroxysmal nocturnal hemoglobinuria inhibits cell-associated fibrinolytic activity

Author keywords

CD87; Paroxysmal nocturnal hemoglobinuria; Thrombosis; Urokinase type plasminogen activator receptor

Indexed keywords

PLASMINOGEN ACTIVATOR RECEPTOR; UNCLASSIFIED DRUG; UROKINASE; UROKINASE RECEPTOR;

EID: 0031127996     PISSN: 09255710     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0925-5710(96)00559-2     Document Type: Article
Times cited : (38)

References (40)
  • 1
    • 0025264867 scopus 로고
    • Phosphatidylinositol-linked proteins and paroxysmal nocturnal hemoglobinuria
    • [1] Rosse WF. Phosphatidylinositol-linked proteins and paroxysmal nocturnal hemoglobinuria. Blood 1990;75:1595-1601.
    • (1990) Blood , vol.75 , pp. 1595-1601
    • Rosse, W.F.1
  • 2
    • 0028884057 scopus 로고
    • The molecular basis of paroxysmal nocturnal hemoglobinuria
    • [2] Rosse WF, Ware RE. The molecular basis of paroxysmal nocturnal hemoglobinuria. Blood 1995;86:3277-3286.
    • (1995) Blood , vol.86 , pp. 3277-3286
    • Rosse, W.F.1    Ware, R.E.2
  • 3
    • 0027310539 scopus 로고
    • Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria
    • [3] Takeda J, Miyata T, Kawagoe K et al. Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria. Cell 1993;73:703-711.
    • (1993) Cell , vol.73 , pp. 703-711
    • Takeda, J.1    Miyata, T.2    Kawagoe, K.3
  • 4
    • 0027412627 scopus 로고
    • The cloning of PIG-A, a component in the early step of GPI-anchor biosynthesis
    • [4] Miyata T, Takeda J, Iida Y et al. The cloning of PIG-A, a component in the early step of GPI-anchor biosynthesis. Science 1993;259:1318-1320.
    • (1993) Science , vol.259 , pp. 1318-1320
    • Miyata, T.1    Takeda, J.2    Iida, Y.3
  • 5
    • 0028057807 scopus 로고
    • Paroxysmal nocturnal haemoglobinuria (PNH) is caused by somatic mutations in the PIG-A gene
    • [5] Bessler M, Mason PJ, Hillmen P et al. Paroxysmal nocturnal haemoglobinuria (PNH) is caused by somatic mutations in the PIG-A gene. EMBO J 1994;13:110-117.
    • (1994) EMBO J , vol.13 , pp. 110-117
    • Bessler, M.1    Mason, P.J.2    Hillmen, P.3
  • 6
    • 0024325872 scopus 로고
    • Paroxysmal nocturnal hemoglobinuria
    • [6] Rotoli B, Luzzatto L. Paroxysmal nocturnal hemoglobinuria. Semin Haematol 1989;26:201-207.
    • (1989) Semin Haematol , vol.26 , pp. 201-207
    • Rotoli, B.1    Luzzatto, L.2
  • 8
    • 0027181250 scopus 로고
    • Complement-induced vesiculation and response of membrane prothrombinase sites in platelets of paroxysmal nocturnal hemoglobinuria
    • [8] Wiedmer T, Hall SE, Ortel TL, Kane WH, Rosse WF, Sims PJ. Complement-induced vesiculation and response of membrane prothrombinase sites in platelets of paroxysmal nocturnal hemoglobinuria. Blood 1993;82:1192-1196.
    • (1993) Blood , vol.82 , pp. 1192-1196
    • Wiedmer, T.1    Hall, S.E.2    Ortel, T.L.3    Kane, W.H.4    Rosse, W.F.5    Sims, P.J.6
  • 9
    • 0026557778 scopus 로고
    • The receptor for urokinase-type plasminogen activator is deficient on peripheral blood leukocytes in patients with paroxysmal nocturnal hemoglobinuria
    • [9] Ploug M, Plesner T, Rønne E et al. The receptor for urokinase-type plasminogen activator is deficient on peripheral blood leukocytes in patients with paroxysmal nocturnal hemoglobinuria. Blood 1992;79:1447-1455.
    • (1992) Blood , vol.79 , pp. 1447-1455
    • Ploug, M.1    Plesner, T.2    Rønne, E.3
  • 11
    • 0024146930 scopus 로고
    • Cell-associated plasminogen activation: Regulation and physiological functions
    • [11] Saksela O, Rifkin DB. Cell-associated plasminogen activation: regulation and physiological functions. Annu Rev Cell Biol 1988;4:93-126.
    • (1988) Annu Rev Cell Biol , vol.4 , pp. 93-126
    • Saksela, O.1    Rifkin, D.B.2
  • 12
    • 0021984227 scopus 로고
    • A cellular binding site for the mr 55000 form of the human plasminogen activator, urokinase
    • [12] Vassalli J-D, Baccino D, Belin D. A cellular binding site for the Mr 55000 form of the human plasminogen activator, urokinase. J Cell Biol 1985;100:86-92.
    • (1985) J Cell Biol , vol.100 , pp. 86-92
    • Vassalli, J.-D.1    Baccino, D.2    Belin, D.3
  • 13
    • 0026063532 scopus 로고
    • Cellular receptor for urokinase plasminogen activator. Carboxyl-terminal processing and membrane anchoring by glycosyl-phosphatidylinositol
    • [13] Ploug M, Rønne E, Behrendt N, Jensen AL, Blasi F, Danø K. Cellular receptor for urokinase plasminogen activator. Carboxyl-terminal processing and membrane anchoring by glycosyl-phosphatidylinositol. J Biol Chem 1991;266:1926-1933.
    • (1991) J Biol Chem , vol.266 , pp. 1926-1933
    • Ploug, M.1    Rønne, E.2    Behrendt, N.3    Jensen, A.L.4    Blasi, F.5    Danø, K.6
  • 14
    • 0026674918 scopus 로고
    • A soluble form of the glycolipid-anchored receptor for urokinase-type plasminogen activator is secreted from peripheral blood leukocytes from patients with paroxysmal nocturnal hemoglobinuria
    • [14] Ploug M, Eriksen J, Plesner T, Hansen NE, Danø K. A soluble form of the glycolipid-anchored receptor for urokinase-type plasminogen activator is secreted from peripheral blood leukocytes from patients with paroxysmal nocturnal hemoglobinuria. Eur J Biochem 1992;208:397-404.
    • (1992) Eur J Biochem , vol.208 , pp. 397-404
    • Ploug, M.1    Eriksen, J.2    Plesner, T.3    Hansen, N.E.4    Danø, K.5
  • 15
    • 0028953704 scopus 로고
    • The receptor for urokinase plasminogen activator is present in plasma from healthy donors and elevated in patients with paroxysmal nocturnal haemoglobinuria
    • [15] Rønne E, Pappot H, Grøndahl-Hansen J et al. The receptor for urokinase plasminogen activator is present in plasma from healthy donors and elevated in patients with paroxysmal nocturnal haemoglobinuria. Br J Haematol 1995;89:576-581.
    • (1995) Br J Haematol , vol.89 , pp. 576-581
    • Rønne, E.1    Pappot, H.2    Grøndahl-Hansen, J.3
  • 16
    • 0023840122 scopus 로고
    • A 55000-60000 Mr receptor protein for urokinase-type plasminogen activator. Identification in human tumor cell lines and partial purification
    • [16] Nielsen LS, Kellerman GM, Behrendt N, Picone R, Danø K, Blasi F. A 55000-60000 Mr receptor protein for urokinase-type plasminogen activator. Identification in human tumor cell lines and partial purification. J Biol Chem 1988;263:2358-2363.
    • (1988) J Biol Chem , vol.263 , pp. 2358-2363
    • Nielsen, L.S.1    Kellerman, G.M.2    Behrendt, N.3    Picone, R.4    Danø, K.5    Blasi, F.6
  • 17
    • 0026662503 scopus 로고
    • Flow cytometric analysis of the urokinase receptor (uPA-R) on tumor cells by fluorescent uPA-ligand or monoclonal antibody #3936
    • [17] Chucholowski N, Schmitt M, Rettenberger P et al. Flow cytometric analysis of the urokinase receptor (uPA-R) on tumor cells by fluorescent uPA-ligand or monoclonal antibody #3936. Fibrinolysis 1992;6(Suppl. 4):95-102.
    • (1992) Fibrinolysis , vol.6 , Issue.SUPPL. 4 , pp. 95-102
    • Chucholowski, N.1    Schmitt, M.2    Rettenberger, P.3
  • 18
    • 0014385564 scopus 로고
    • Isolation of mononuclear cell and granulocyte from human blood
    • [18] Böyum A. Isolation of mononuclear cell and granulocyte from human blood. Scand J Clin Lab Invest 1967;21(Suppl. 97):77-89.
    • (1967) Scand J Clin Lab Invest , vol.21 , Issue.SUPPL. 97 , pp. 77-89
    • Böyum, A.1
  • 19
    • 0029074566 scopus 로고
    • Enzyme-linked immunosorbent assay detection of a soluble form of urokinase plasminogen activator receptor in vivo
    • [19] Mizukami IF, Faulkner NE, Gyetko MR, Sitrin RG, Todd RF III. Enzyme-linked immunosorbent assay detection of a soluble form of urokinase plasminogen activator receptor in vivo. Blood 1995;86:203-211.
    • (1995) Blood , vol.86 , pp. 203-211
    • Mizukami, I.F.1    Faulkner, N.E.2    Gyetko, M.R.3    Sitrin, R.G.4    Todd R.F. III5
  • 20
    • 0026507207 scopus 로고
    • Increased plasma decay-accelerating factor levels in paroxysmal nocturnal hemoglobinuria
    • [20] Nakakuma H, Nagakura S, Kawaguchi T et al. Increased plasma decay-accelerating factor levels in paroxysmal nocturnal hemoglobinuria. Int J Hematol 1992;55:121-125.
    • (1992) Int J Hematol , vol.55 , pp. 121-125
    • Nakakuma, H.1    Nagakura, S.2    Kawaguchi, T.3
  • 21
    • 0028567891 scopus 로고
    • Expression of the receptor for urokinase-type plasminogen activator in normal and neoplastic blood cells and hematopoietic tissue
    • [21] Plesner T, Ralfkiaer E, Wittrup M et al. Expression of the receptor for urokinase-type plasminogen activator in normal and neoplastic blood cells and hematopoietic tissue. Am J Clin Pathol 1994;102:835-841.
    • (1994) Am J Clin Pathol , vol.102 , pp. 835-841
    • Plesner, T.1    Ralfkiaer, E.2    Wittrup, M.3
  • 22
    • 0027076170 scopus 로고
    • The urokinase receptor: Involvement in cell surface proteolysis and cancer invasion
    • [22] Ellis V, Pyke C, Eriksen J, Solberg H, Danø K. The urokinase receptor: involvement in cell surface proteolysis and cancer invasion. Ann NY Acad Sci 1992;667:13-31.
    • (1992) Ann NY Acad Sci , vol.667 , pp. 13-31
    • Ellis, V.1    Pyke, C.2    Eriksen, J.3    Solberg, H.4    Danø, K.5
  • 23
    • 0027215058 scopus 로고
    • Receptor for urokinase is present in tissue-associated macrophages in ductal breast carcinoma
    • [23] Pyke C, Graem N, Ralfkiaer E et al. Receptor for urokinase is present in tissue-associated macrophages in ductal breast carcinoma. Cancer Res 1993;53:1911-1915.
    • (1993) Cancer Res , vol.53 , pp. 1911-1915
    • Pyke, C.1    Graem, N.2    Ralfkiaer, E.3
  • 24
    • 0028327420 scopus 로고
    • The receptor for urokinase-type plasminogen activator is expressed by keratinocytes at the leading edge during re-epithelialization of mouse skin wound
    • [24] Romer J, Lund LR, Eriksen J, Pyke C, Kristensen P, Danø K. The receptor for urokinase-type plasminogen activator is expressed by keratinocytes at the leading edge during re-epithelialization of mouse skin wound. J Invest Dermatol 1994;102:519-522.
    • (1994) J Invest Dermatol , vol.102 , pp. 519-522
    • Romer, J.1    Lund, L.R.2    Eriksen, J.3    Pyke, C.4    Kristensen, P.5    Danø, K.6
  • 25
    • 0028070859 scopus 로고
    • Prognostic impact of urokinase, urokinase receptor and type 1 plasminogen activator inhibitor in squamous and large cell lung cancer tissue
    • [25] Pedersen H, Brunner N, Francis D et al. Prognostic impact of urokinase, urokinase receptor and type 1 plasminogen activator inhibitor in squamous and large cell lung cancer tissue. Cancer Res 1994;54:4671-4675.
    • (1994) Cancer Res , vol.54 , pp. 4671-4675
    • Pedersen, H.1    Brunner, N.2    Francis, D.3
  • 26
    • 0025853770 scopus 로고
    • Urokinase-type plasminogen activator is expressed in stromal cells and its receptor in cancer cells at invasive foci in human colon adenocarcinomas
    • [26] Pyke C, Kristensen P, Ralfkiaer E et al. Urokinase-type plasminogen activator is expressed in stromal cells and its receptor in cancer cells at invasive foci in human colon adenocarcinomas. Am J Pathol 1991;138:1059-1067.
    • (1991) Am J Pathol , vol.138 , pp. 1059-1067
    • Pyke, C.1    Kristensen, P.2    Ralfkiaer, E.3
  • 27
    • 0023223148 scopus 로고
    • The receptor-binding sequence of urokinase. A biological function for the growth-factor module of proteases
    • [27] Appella E, Robinson EA, Ullrich SJ et al. The receptor-binding sequence of urokinase. A biological function for the growth-factor module of proteases. J Biol Chem 1987;262:4437-4440.
    • (1987) J Biol Chem , vol.262 , pp. 4437-4440
    • Appella, E.1    Robinson, E.A.2    Ullrich, S.J.3
  • 28
    • 0029294650 scopus 로고
    • The structure and function of the urokinase receptor, a membrane protein governing plasminogen activation on the cell surface
    • [28] Behrendt N, Rønne E, Danø K. The structure and function of the urokinase receptor, a membrane protein governing plasminogen activation on the cell surface. Biol Chem (Hoppe-Seyler) 1995;376:269-279.
    • (1995) Biol Chem (Hoppe-seyler) , vol.376 , pp. 269-279
    • Behrendt, N.1    Rønne, E.2    Danø, K.3
  • 29
    • 0023034961 scopus 로고
    • Binding of single-chain prourokinase to the urokinase receptor of human U937 cells
    • [29] Cubellis MV, Nolli ML, Cassanig G, Blasi F. Binding of single-chain prourokinase to the urokinase receptor of human U937 cells. J Biol Chem 1986;261:15819-15822.
    • (1986) J Biol Chem , vol.261 , pp. 15819-15822
    • Cubellis, M.V.1    Nolli, M.L.2    Cassanig, G.3    Blasi, F.4
  • 30
    • 0022336533 scopus 로고
    • Evidence for occupancy with endogenous urokinase of urokinase binding sites on human foreskin cells
    • [30] Bajpai A, Baker JB. Evidence for occupancy with endogenous urokinase of urokinase binding sites on human foreskin cells. Biochem Biophys Res Commun 1985;133:994-1000.
    • (1985) Biochem Biophys Res Commun , vol.133 , pp. 994-1000
    • Bajpai, A.1    Baker, J.B.2
  • 31
    • 0001149917 scopus 로고
    • Differentiation-enhanced binding of the amino-terminal fragment of human urokinase plasminogen activator to a specific receptor on u937 monocytes
    • [31] Stoppelli MP, Corti A, Soffientini A, Cassani G, Blasi F, Assoian RK. Differentiation-enhanced binding of the amino-terminal fragment of human urokinase plasminogen activator to a specific receptor on U937 monocytes. Proc Natl Acad Sci USA 1985;82:4939-4943.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 4939-4943
    • Stoppelli, M.P.1    Corti, A.2    Soffientini, A.3    Cassani, G.4    Blasi, F.5    Assoian, R.K.6
  • 33
    • 0024435761 scopus 로고
    • Functional characteristics of receptor-bound urokinase on human monocytes: Catalytic efficiency and susceptibility to inactivation by plasminogen activator inhibitors
    • [33] Kirchheimer JC, Remold HG. Functional characteristics of receptor-bound urokinase on human monocytes: catalytic efficiency and susceptibility to inactivation by plasminogen activator inhibitors. Blood 1989;74:1396-1402.
    • (1989) Blood , vol.74 , pp. 1396-1402
    • Kirchheimer, J.C.1    Remold, H.G.2
  • 34
    • 0025373787 scopus 로고
    • Interaction of single-chain urokinase-type plasminogen activator with human endothelial cells
    • [34] Barnathan ES, Kou A, Rosenfeld L et al. Interaction of single-chain urokinase-type plasminogen activator with human endothelial cells. J Biol Chem 1990;265:2865-2872.
    • (1990) J Biol Chem , vol.265 , pp. 2865-2872
    • Barnathan, E.S.1    Kou, A.2    Rosenfeld, L.3
  • 35
    • 0027956663 scopus 로고
    • Characterization of plasminogen activation by glycosylphosphatidylinositol-anchored urokinase
    • [35] Lee SW, Ellis V, Dichek DA. Characterization of plasminogen activation by glycosylphosphatidylinositol-anchored urokinase. J Biol Chem 1994;269:2411-2418.
    • (1994) J Biol Chem , vol.269 , pp. 2411-2418
    • Lee, S.W.1    Ellis, V.2    Dichek, D.A.3
  • 36
    • 0029913282 scopus 로고    scopus 로고
    • Single-chain urokinase-type plasminogen activator bound to its receptor is relatively resistant to plasminogen activator inhibitor type 1
    • [36] Higazi AAR, Mazar A, Wang J et al. Single-chain urokinase-type plasminogen activator bound to its receptor is relatively resistant to plasminogen activator inhibitor type 1. Blood 1996;87:3545-3549.
    • (1996) Blood , vol.87 , pp. 3545-3549
    • Higazi, A.A.R.1    Mazar, A.2    Wang, J.3
  • 37
    • 0025273735 scopus 로고
    • Receptor-mediated internalization and degradation of urokinase is caused by its specific inhibitor PAI-1
    • [37] Cubellis MV, Wun T-C, Blasi F. Receptor-mediated internalization and degradation of urokinase is caused by its specific inhibitor PAI-1. EMBO J 1990;9:1079-1085.
    • (1990) EMBO J , vol.9 , pp. 1079-1085
    • Cubellis, M.V.1    Wun, T.-C.2    Blasi, F.3
  • 38
    • 0026439778 scopus 로고
    • Ldl receptor-related protein internalizes and degrades uPA:PAI-1 complexes and is essential for embryo implantation
    • [38] Herz J, Clouthier DE, Hammer RE. LDL receptor-related protein internalizes and degrades uPA:PAI-1 complexes and is essential for embryo implantation. Cell 1992;71:411-421.
    • (1992) Cell , vol.71 , pp. 411-421
    • Herz, J.1    Clouthier, D.E.2    Hammer, R.E.3
  • 39
    • 0024316809 scopus 로고
    • The glycosyl-phosphatidylinositol anchor of membrane proteins
    • [39] Low MG. The glycosyl-phosphatidylinositol anchor of membrane proteins. Biochim Biophys Acta 1989;988:427-454.
    • (1989) Biochim Biophys Acta , vol.988 , pp. 427-454
    • Low, M.G.1
  • 40
    • 0001353920 scopus 로고
    • Purified α2-macroglobulin receptor/LDL receptor-related protein binds urokinase:Plasminogen activator inhibitor type 1 complex
    • [40] Nykjaer A, Petersen CM, Moller B et al. Purified α2-macroglobulin receptor/LDL receptor-related protein binds urokinase:plasminogen activator inhibitor type 1 complex. J Biol Chem 1992;267:14543-14546.
    • (1992) J Biol Chem , vol.267 , pp. 14543-14546
    • Nykjaer, A.1    Petersen, C.M.2    Moller, B.3


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