Siglecs in the immune system

Immunology

Volumn 103, Issue 2, 2001, Pages 137-145

  Crocker, Paul R ^a   Varki, Ajit ^b  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b University of California San Diego   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD22 ANTIGEN; CD33 ANTIGEN; LECTIN; SIALIC ACID; SIALIC ACID BINDING IMMUNOGLOBULIN LIKE LECTIN DERIVATIVE; UNCLASSIFIED DRUG;

ANTIGEN BINDING; B LYMPHOCYTE; CELL INTERACTION; HUMAN; IMMUNE SYSTEM; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; REVIEW;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD22; ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; B-LYMPHOCYTES; CELL ADHESION MOLECULES; CELL COMMUNICATION; HUMANS; IMMUNE SYSTEM; LECTINS; MICE; N-ACETYLNEURAMINIC ACID; SIGNAL TRANSDUCTION;

EID: 0035015565     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0019-2805.2001.01241.x     Document Type: Review

References (84)

1. Siglecs: A family of sialic-acid binding lectins [letter]
2. I-type lectins
3. Crystal structure of the N-terminal domain of sialoadhesin in complex with 3′ sialyllactose at 1.85 Å resolution
4. Properties and distribution of a lectin-like hemagglutinin differentially expressed by murine stromal tissue macrophages
5. The B-cell antigen CD22 mediates monocyte and erythrocyte adhesion
6. Purification and properties of sialoadhesin, a sialic acid-binding receptor of murine tissue macrophages
7. Sialoadhesin binds preferentially to cells of the granulocytic lineage
8. Natural ligands of the B cell adhesion molecule CD22 beta carry N-linked oligosaccharides with alpha-2,6-linked sialic acids that are required for recognition
9. CD22, a B cell-specific immunoglobulin superfamily member, is a sialic acid-binding lectin
10. The oligosaccharide binding specificities of CD22 beta, a sialic acid-specific lectin of B cells
11. Sialoadhesin, a macrophage sialic acid binding receptor for haemopoietic cells with 17 immunoglobulin-like domains
12. Sialoadhesin, myelin-associated glycoprotein and CD22 define a new family of sialic acid-dependent adhesion molecules of the immunoglobulin superfamily
13. Characterization of CD33 as a new member of the sialoadhesin family of cellular interaction molecules
14. Sialic acids in molecular and cellular interactions
15. Chemistry, biochemistry and biology of sialic acids
16. Sialic acids
17. OB-BP1/Siglec-6. A leptin- and sialic acid-binding protein of the immunoglobulin superfamily
18. The same epitope on CD22 of B lymphocytes mediates the adhesion of erythrocytes, T and B lymphocytes, neutrophils, and monocytes
19. Ig domains 1 and 2 of murine CD22 constitute the ligand-binding domain and bind multiple sialylated ligands expressed on B and T cells
20. Cytokine-induced beta-galactoside alpha-2,6-sialyltransferase in human endothelial cells mediates alpha 2,6-sialylation of adhesion molecules and CD22 ligands
21. Binding of human plasma sialoglycoproteins by the B cell-specific lectin CD22. Selective recognition of immunoglobulin M and haptoglobin
22. Immune regulation by the ST6Gal sialyltransferase
23. CD22-mediated cell adhesion to cytokine-activated human endothelial cells. Positive and negative regulation by alpha 2-6-sialylation of cellular glycoproteins
24. Regulation of CD45 engagement by the B-cell receptor CD22
25. Masking and unmasking of the sialic acid-binding lectin activity of CD22 (Siglec-2) on B lymphocytes
26. A novel subset of murine B cells that expresses unmasked forms of CD22 is enriched in the bone marrow: Implications for B-cell homing to the bone marrow
27. Cryptic sialic acid binding lectins on human blood leukocytes can be unmasked by sialidase treatment or cellular activation
28. Characterization of human sialoadhesin, a sialic acid binding receptor expressed by resident and inflammatory macrophage populations
29. Macrophage-tumour cell interactions: Identification of MUC1 on breast cancer cells as a potential counter-receptor for the macrophage- restricted receptor, sialoadhesin
30. Sialoadhesin-positive host macrophages play an essential role in graft-versus-leukemia reactivity in mice
31. CD43 functions as a T cell counter-receptor for the macrophage adhesion receptor sialoadhesin (siglec-1)
32. CD22 is a negative regulator of B-cell receptor signalling
33. Identification of CD22 ligands on bone marrow sinusoidal endothelium implicated in CD22-dependent homing of recirculating B cells
34. Apoptosis and macrophage-mediated cell deletion in the regulation of B lymphopoiesis in mouse bone marrow
35. Immune inhibitory receptors
36. Hyperresponsive B cells in CD22-deficient mice
37. CD22 regulates thymus-independent responses and the lifespan of B cells
38. CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: Altered signaling in CD22-deficient mice
39. Deficiency in CD22, a B cell-specific inhibitory receptor, is sufficient to predispose to development of high affinity autoantibodies
40. Association of CD22 with the B cell antigen receptor
41. CD22 associates with the human surface IgM-B-cell antigen receptor complex
42. Inhibition of the B cell by CD22: A requirement for Lyn
43. Tuning antigen receptor signaling by CD22: Integrating cues from antigens and the microenvironment
44. CD22 forms a quaternary complex with SHIP, Grb2, and Shc. A pathway for regulation of B lymphocyte antigen receptor-induced calcium flux
45. Analysis of tyrosine phosphorylation-dependent interactions between stimulatory effector proteins and the B cell co-receptor CD22
46. A role in B cell activation for CD22 and the protein tyrosine phosphatase SHP
47. Counterregulation by the coreceptors CD19 and CD22 of MAP kinase activation by membrane immunoglobulin
48. Characterization of siglec-5, a novel glycoprotein expressed on myeloid cells related to CD33
49. Identification and characterization of a novel siglec, siglec-7, expressed by human natural killer cells and monocytes
50. Siglec-8. A novel eosinophil-specific member of the immunoglobulin superfamily
51. Identification of SAF-2, a novel siglec expressed on eosinophils, mast cells, and basophils
52. Siglec-7: A sialic acid-binding lectin of the immunoglobulin superfamily
53. Identification, characterisation and leucocyte expression of Siglec-10, a novel human sialic acid binding receptor
54. Identification and molecular cloning of p75/AIRM1, a novel member of the sialoadhesin family that functions as an inhibitory receptor in human natural killer cells
55. Identification and molecular characterization of a novel member of the siglec family (SIGLEC9)
56. Cloning, characterization, and phylogenetic analysis of siglec-9, a new member of the CD33-related group of siglecs. Evidence for co-evolution with sialic acid synthesis pathways
57. Siglec-9, a novel sialic acid binding member of the immunoglobulin superfamily expressed broadly on human blood leukocytes
58. Molecular cloning of MIS, a myeloid inhibitory siglec that binds tyrosine phosphatases SHP-1 and SHP-2
59. mSiglec-E, a novel mouse CD33-related siglec (sialic acid binding immunoglobulin-like lectin) that recruits Src homology 2 (SH2) -domain containing protein tyrosine phosphatases SHP-1 and SHP-2
60. Initial sequencing and analysis of the human genome
61. Molecular cloning of two isoforms of the murine homolog of the myeloid CD33 antigen
62. Engagement of p75/AIRM 1 or CD33 inhibits the proliferation of normal of leukemic myeloid cells [In Process Citation]
63. Molecular characterizadon of a siglec8 variant containing cytoplasmic tyrosine-based motifs, and mapping of the siglec8 gene
64. The myeloid-specific sialic acid-binding receptor, CD33, associates with the protein-tyrosine phosphatases SHP-1 and SHP-2
65. The sialoadhesin CD33 is a myeloid-specific inhibitory receptor
66. Myeloid specific human CD33 is an inhibitory receptor with differential ITIM function in recruiting the phosphatases SHP-1 and SHP-2
67. The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM
68. Host response to EBV infection in X-linked lymphoproliferative disease results from mutations in an SH2-domain encoding gene
69. Engagement of CD33 surface molecules prevents the generation of dendritic cells from both monocytes and CD34+ myeloid precursors [In Process Citation]
70. Human signal-regulatory protein is expressed on normal, but not on subsets of leukemic myeloid cells and mediates cellular adhesion involving its counterreceptor CD47
71. Integrin-associated protein is a ligand for the P84 neural adhesion molecule
72. CD47 is a ligand for rat macrophage membrane signal regulatory protein SIRP (OX41) and human SIRPalpha 1
73. Role of CD47 asa marker of self on red blood cells
74. Lymphoid/neuronal cell surface OX2 glycoprotein recognizes a novel receptor on macrophages implicated in the control of their function
75. Putting the brakes on innate immunity: A regulatory role for CD200
76. Down-regulation of the macrophage lineage through interaction with OX2 (CD200)
77. New aspects of siglec binding specificities, including the significance of fucosylation and of the sialyl-Tn epitope. Sialic acid-binding immunoglobulin superfamily lectins
78. Specialized contributions by alpha (1, 3)-fucosyltransferase-IV and FucT-VII during leukocyte rolling in dermal microvessels
79. Modifications of cell surface sialic acids modulate cell adhesion mediated by sialoadhesin and CD22
80. Sialic acid 9-O-acetylation on murine erythroleukemia cells affects complement activation, binding to I-type lectins, and tissue homing
81. Functional groups of sialic acids involved in binding to siglecs (sialoadhesins) deduced from interactions with synthetic analogues
82. Localization of the putative sialic acid-binding site on the immunoglobulin superfamily cell-surface molecule CD22
83. Loss of N-glycolyl-neuraminic acid in human evolution. Implications for sialic acid recognition siglecs
84. Myelin-associated glycoprotein: A role in myelination and in the inhibition of axonal regeneration?