Identification of CD22 ligands on bone marrow sinusoidal endothelium implicated in CD22-dependent homing of recirculating B cells

Journal of Experimental Medicine

Volumn 189, Issue 9, 1999, Pages 1513-1518

  Nitschke, Lars ^a   Floyd, Helen ^b   Ferguson, David J P ^c   Crocker, Paul R ^b  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

B cells; CD22; Lymphocyte homing; Sialic acid binding; Siglec

Indexed keywords

CD22 ANTIGEN; FC RECEPTOR; LIGAND; SIALIC ACID;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; BONE MARROW CELL; ENDOTHELIUM CELL; FLOW CYTOMETRY; LYMPHOCYTE HOMING; MOUSE; NONHUMAN; PLASMA CELL; PRIORITY JOURNAL;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD22; ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE; B-LYMPHOCYTES; BONE MARROW; CELL ADHESION MOLECULES; CELL MOVEMENT; CHO CELLS; CRICETINAE; ENDOTHELIUM; LECTINS; LIGANDS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; N-ACETYLNEURAMINIC ACID;

EID: 0033519233     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.189.9.1513     Document Type: Article

References (25)

1. Cyster, J.G., and C.C. Goodnow. 1997. Tuning antigen receptor signaling by CD22: integrating cues from antigens and the microenvironment. Immunity. 6:509-517.
2. Doody, G.M., L.B. Justement, C.C. Delibrias, R.J. Matthews, J. Lin, M.L. Thomas, and D.T. Fearon. 1995. A role in B cell activation for CD22 and the protein tyrosine phosphatase SHP. Science. 269:242-244.
3. Nitschke, L., R. Carsetti, B. Ocker, G. Köhler, and M.C. Lamers. 1997. CD22 is a negative regulator of B-cell receptor signalling. Curr. Biol. 7:133-143.
4. O'Keefe, T.L., G.T. Williams, S.L. Davies, and M.S. Neuberger. 1996. Hyperresponsive B cells in CD22-deficient mice. Science. 274:798-801.
5. Otipoby, K.L., K.B. Andersson, K.E. Draves, S.J. Klaus, A.G. Farr, J.D. Kerner, R.M. Perlmutter, C.L. Law, and E.A. Clark. 1996. CD22 regulates thymus-independent responses and the lifespan of B cells. Nature. 384:634-637.
6. Sato, S., A.S. Miller, M. Inaoki, C.B. Bock, P.J. Jansen, M.L. Tang, and T.F. Tedder. 1996. CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice. Immunity. 5:551-562.
7. Crocker, P.R., E.A. Clark, M. Filbin, S. Gordon, Y. Jones, J.H. Kehrl, S. Kelm, N. Le Douarin, L. Powell, J. Roder, et al. 1998. Siglecs: a family of sialic-acid binding lectins. Glycobiology. 8:v.
8. Kelm, S., A. Pelz, R. Schauer, M.T. Filbin, S. Tang, M.E. de Bellard, R.L. Schnaar, J.A. Mahoney, A. Hartnell, P. Bradfield, and P.R. Crocker. 1994. Sialoadhesin, myelin-associated glycoprotein and CD22 define a new family of sialic acid-dependent adhesion molecules of the immunoglobulin superfamily. Curr. Biol. 4:965-972.
9. Hanasaki, K., A. Varki, and L.D. Powell. 1995. CD22-mediated cell adhesion to cytokine-activated human endothelial cells. Positive and negative regulation by alpha 2-6-sialylation of cellular glycoproteins. J. Biol. Chem. 270:7533-7542.
10. Powell, L.D., and A. Varki. 1994. The oligosaccharide binding specificities of CD22 beta, a sialic acid-specific lectin of B cells. J. Biol. Chem. 269:10628-10636.
11. 2-terminal signal anchor. J. Biol. Chem. 262:17735-17743.
12. Sgroi, D., G.A. Koretzky, and I. Stamenkovic. 1995. Regulation of CD45 engagement by the B-cell receptor CD22. Pm. Natl. Acad. Sci. USA. 92:4026-4030.
13. Razi, N., and A. Varki. 1998. Masking and unmasking of the sialic acid-binding lectin activity of CD22 (Siglec-2) on B lymphocytes. Proc. Natl. Acad. Sci. USA. 95:7469-7474.
14. Carsetti, R., G. Köhler, and M.C. Lamers. 1995. Transitional B cells are the target of negative selection in the B cell compartment. J. Exp. Med. 181:2129-2140.
15. Osmond, D.G., S. Rico-Vargas, H. Valenzona, L. Fauteux, L. Liu, R. Janani, L. Lu, and K. Jacobsen. 1994. Apoptosis and macrophage-mediated cell deletion in the regulation of B lymphopoiesis in mouse bone marrow. Immunol. Rev. 142: 209-230.
16. MacLennan, I.C. 1998. B-cell receptor regulation of peripheral B cells. Curr. Opin. Immunol. 10:220-225.
17. van der Merwe, P.A., P.R. Crocker, M. Vinson, A.N. Barclay, R. Schauer, and S. Kelm. 1996. Localization of the putative sialic acid-binding site on the immunoglobulin superfamily cell-surface molecule CD22. J. Biol. Chem. 271: 9273-9280.
18. Bebbington, C. 1991. Expression of antibody genes in non-lymphoid mammalian cells. In Methods: A Companion to Methods in Enzymology. Academic Press, London/New York. 136-145.
19. Sedgwick, J.D., and P.G. Holt. 1983. A solid-phase immunoenzymatic technique for the enumeration of specific antibody-secreting cells. J. Immunol. Methods. 57:301-309.
20. Sjoberg, E.R., L.D. Powell, A. Klein, and A. Varki. 1994. Natural ligands of the B cell adhesion molecule CD22 beta can be masked by 9-O-acetylation of sialic acids. J. Cell Biol. 126:549-562.
21. Fischer, E., and R. Brossmer. 1995. Sialic acid-binding lectins: submolecular specificity and interaction with sialoglycoproteins and tumour cells. Glycoconj. J. 12:707-713.
22. Benner, R., W. Hijmans, and J.J. Haaijman. 1981. The bone marrow: the major source of serum immunoglobulins, but still a neglected site of antibody formation. Clin. Exp. Immunol. 46:1-8.
23. Hennet, T., D. Chui, J.C. Paulson, and J.D. Marth. 1998. Immune regulation by the ST6Gal sialyltransferase. Proc. Natl. Acad. Sci. USA. 95:4504-4509.
24. + B cells, the major B cell subset in the peripheral blood, express V kappa genes with no or little somatic mutation throughout life. Eur. J. Immunol. 23:3272-3277.
25. Paramithiotis, E., and M.D. Cooper. 1997. Memory B lymphocytes migrate to bone marrow in humans. Proc. Natl. Acad. Sci. USA. 94:208-212.