Crystal structure of the N-terminal domain of sialoadhesin in complex with 3′ sialyllactose at 1.85 å resolution

Molecular Cell

Volumn 1, Issue 5, 1998, Pages 719-728

  May, A P ^e   Robinson, R C ^a   Vinson, M ^b,c   Crocker, P R ^b,d   Jones, E Y ^e  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c GLAXOSMITHKLINE   (United Kingdom)

^d UNIVERSITY OF DUNDEE   (United Kingdom)

^e NONE

Author keywords

[No Author keywords available]

Indexed keywords

CELL ADHESION MOLECULE; CELL SURFACE RECEPTOR; ERYTHROCYTE RECEPTOR; IMMUNOGLOBULIN RECEPTOR; MEMBRANE PROTEIN;

ANIMAL; ARTICLE; CELL STRAIN COS1; CHEMISTRY; CRYSTALLOGRAPHY; GENETICS; MOLECULAR GENETICS; MULTIGENE FAMILY; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; ULTRASTRUCTURE;

ANIMALS; CELL ADHESION MOLECULES; COS CELLS; CRYSTALLOGRAPHY; MEMBRANE GLYCOPROTEINS; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CELL SURFACE; RECEPTORS, IMMUNOLOGIC; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0032037915     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)80071-4     Document Type: Article

References (60)

1. Bacon, D.J., and Anderson, W.F. (1988). A fast algorithm for rendering space filling molecule pictures. J. Mol. Graph. 6, 219-220.
2. Bebbington, C.R. (1991). Expression of antibody genes in non-lymphoid mammalian cells. Methods 2, 136-145.
3. Bevilaqua, M.P., and Nelson, R.M. (1993). Selectins. J. Clin. Invest. 91, 379-387.
4. Blanck, O., Lobst, S.T., Gabel, C., and Drickamer, K. (1996). Introduction of selectin-like binding-specificity into a homologous mannose-binding protein. J. Biol. Chem. 271, 7289-7292.
5. Brandley, B.K., Kiso, M., Abbas, S., Nikrad, P., Srivasatava, O., Foxall, C., Oda, Y., and Hasegawa, A. (1993). Glycobiology 3, 633-639.
6. Brünger, A.T. (1992a). XPLOR, version 3.1 : a system for X-ray crystallography and NMR (Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut).
7. Brünger, A.T. (1992b). The free Rvalue: a novel statistical quantity for assessing the accuracy of crystal structures. Nature 355, 472-475.
8. Brünger, A.T., Krukowski, A., and Erickson, J.W. (1990). Slow-cooling protocols for crystallographic refinement by simulated annealing. Acta Cryst. A46, 585-593.
9. Collaborative Computational Project No.4 (1994). The CCP4 suite: programs for protein crystallography. Acta Cryst. D50, 760-763.
10. Collins, B.E., Kiso, M., Hasegawa, A., Tropak, M.B., Roder, J.C., Crocker, P.R., and Schnarr, R.L. (1997a). Binding specificities of the sialoadhesin family of I-type lectins-Sialic acid linkage and substructure requirements for binding of myelin-associated glycoprotein, schwann cell myelin protein, and sialoadhesin. J. Biol. Chem. 272, 16889-16895.
11. Collins, B.E., Yang, L.J.S., Mukhopadhyay, G., Filbin, M.T., Kiso, M., Hasegawa, A., and Schnaar R.L. (1997b). Sialic acid binding specificity of myelin-associated glycoprotein binding. J. Biol. Chem. 272, 1248-1255.
12. Crocker, P.R., Kelm, S., Dubois, C., Martin, B., McWilliam, A., Shotton, D.M., Paulson, J.C., and Gordon, S. (1991). Purification and properties of sialoadhesin, a sialic acid-binding receptor of murine tissue macrophages. EMBO J. 10, 1661-1669.
13. Crocker, P.R., Mucklow, S., Bouckson, V., McWilliam, A., Willis, A.C., Gordon, S., Milon, G., Kelm, S., and Bradfield, P. (1994). Sialoadhesin, a macrophage sialic-acid-binding receptor for haemopoetic cells with 17 immunoglobulin-like domains. EMBO J. 13, 4490-4503.
14. Crocker, P.R., Freeman, S., Gordon, S.,and Kelm, S. (1995). Sialoadhesin binds preferentially to cells of the granulocytic lineage. J. Clin. Invest. 95, 635-643.
15. Crocker, P.R., Hartnell, A., Munday, J., and Nath, D. (1997). The potential role of sialoadhesin as a macrophage recognition molecule in health and disease. Glycoconj. J. 14, 601-609.
16. Crocker, P.R., Clark, E.A., Filbin, M., Gordon, S., Jones, E.Y., Kehrl, J.H., Kelm, S., Le Douarin, N., Powell, L., Roder, J., et al. (1998). Siglecs: a family of sialic-acid binding lectins. Glycobiology 8, v.
17. Cyster, J.G., and Goodnow, C.C. (1997). Tuning antigen receptor signaling by CD22: integrating cues from antigens and the microenvironment. Immunity 6, 509-517.
18. Esnouf, R.M. (1997). An extensively modified version of molscript which includes greatly enhanced colouring capabilities. J. Mol. Graph. 15, 133-138.
19. Freeman, S.D., Kelm, S., Barber, E.K., and Crocker, P.R. (1995). Characterisation of CD33 as a new member of the sialoadhesin family of cellular interaction molecules. Blood 85, 2005-2012.
20. Graves, B.J., Crowther, R.L., Chandran, C., Rumberger, J.M., Li, S., Huang, K.-S., Presky, D.H., Familletti, P.C., Wolitzky, B.A., and Burns, D.K. (1994). Insight into E-selectin/ligand interaction from the crystal structure and mutagensis of the lec/EGF domains. Nature 367, 532-538.
21. Harlos, K. (1992). Micro-bridges for sitting drop crystallization. J. Appl. Cryst. 25, 536-538.
22. Higuchi, R., Krummel, B., and Saiki, R.H. (1988). A general method of in vitro preparation and specific mutagenesis of DNA fragments: a study of protein and DNA interactions. Nucleic Acids Res. 16, 7351-7367.
23. Ho, S.N., Hunt, R.M., Pullen, J.K., and Pease, L.R. (1989). Site-directed mutagensis by overlap extension using the polymerase chain reaction. Gene 77, 51-59.
24. Holm, L., and Sander, C. (1993). Protein structure comparison by alignment of distance matches. J. Mol. Biol. 233, 123-138.
25. Jones, T.A., Zou, J.-Y., Cowan, S., and Kjeldgaard, M. (1991). Improved methods for building protein models in electron-density maps and the location of errors in these models. Acta Cryst. A47, 110-119.
26. Kelm, S., Pelz, A., Schauer, R., Filbin, M.T., Tang, S., Bellard, M.-E.D., Schnarr, R.I., Mahoney, J.A., Hartnell, A., Bradfield, P., and Crocker, P.R. (1994a). Sialoadhesin, MAG and CD22 define a new family of sialic acid-dependent adhesion molecules of the immunoglobulin superfamily. Curr. Biol. 4, 965-972.
27. Kelm, S., Schauer, R., Manuguerra, J.C., Gross, H.J., and Crocker, P.R. (1994b). Modifications of cell surface sialic acids modulate cell adhesion mediated by sialoadhesin and CD22. Glycoconj. J. 11, 576-585.
28. Kunkel, T.A. (1985). Rapid and efficient site-specific mutagenesis without phenotypic selection. Proc. Natl. Acad. Sci. USA 82, 488-492.
29. Laskowski, R.A., MacArthur, M.W., Moss, D.S., and Thornton, J.M. (1993). PROCHECK, a program to check the stereochemical quality of protein structures. J. Appl. Cryst. 26, 283-291.
30. Lasky, L.A. (1992). Selectins: interpreters of cell-specific carbohydrate information during inflammation. Science 258, 964-969.
31. Li, C.M., Tropak, M.B., Gerlai, R., Clapoff, S., Abramownewerly, W., Trapp, B., Peterson, A., and Roder, J. (1994). Myelination in the absence of myelin-associated glycoprotein. Nature 369, 747-750.
32. May, A.P., Robinson, R.C., Bradfield, P., Aplin, R.T., Crocker, P.R., and Jones, E.Y. (1997). Expression, purification, crystallisation and preliminary x-ray analysis of a sialic acid binding fragment of sialoadhesin in the presence and absence of ligand. Protein Sci. 6, 717-721.
33. McEver, R.P. (1994). Selectins. Curr Opin. Immunol. 6, 75-84.
34. Merrit, E.A., and Murphy, M.E.P. (1994). Raster3D version 2.0: a program for photorealistic molecular graphics. Acta. Cryst. D50, 869-873.
35. Montag, D., Giese, K.P., Bartsch, U., Martini, R., Lang, Y., Bluthmann, H., Karthigasan, J., Kirschener, D.A., Wintergerst, E.S., Nave, K.A., et al. (1994). Mice deficient for the myelin-associated glycoprotein show subtle abnormalities in myelin. Neuron 13, 229-246.
36. Nath, D., van der Merwe, P.A., Kelm, S., Bradfield, P., and Crocker, P.R. (1995). The amino-terminal immunoglobulin-like domain of sialoadhesin contains the sialic acid binding site. J. Biol. Chem. 270, 26184-26191.
37. Navaza, J. (1994). AmORE: an automated package for molecular replacement. Acta. Cryst. A50, 157-163.
38. Ng, K.K.S., and Weis, W.I. (1997). Structure of a selectin-like mutant of mannose-binding protein complexed with sialyllated and sulphated oligosaccharides. Biochemistry 36, 979-988.
39. Otwinowski Z., and Minor, W. (1997). Processing of X-ray diffraction data collected in oscillation mode. Meth. Enzymol. 276, 307-326.
40. Powell, L.D., and Varki, A. (1994). The oligosaccharide binding specificities of CD22b, a sialic acid-specific lectin of B cells. J. Biol. Chem. 269, 10628-10636.
41. Powell, L.D., Jain, R.K., Matta, K.I., Sabesan, S., and Varki, A. (1995). Characterization of sialyloligosaccharide binding by recombinant soluble and native cell-associated CD22. J. Biol. Chem. 270, 7523-7532.
42. Richardson, J.S. (1981). The anatomy and taxonomy of protein-structure. Adv. Prot. Chem. 34, 167-339.
43. Sauter, N.K., Hanson, J.E., Glick, G.D., Brown, J.H., Crowther, R.L., Park, S.-J., Skehel, J.J., and Wiley, D.C. (1992). Binding of influenza virus haemagglutinin to analogues of its cell surface receptor, sialic acid: analysis by proton nuclear magnetic resonance spectroscopy and x-ray crystallography. Biochemistry 31, 9609-9621.
44. Shapiro, L., Fannon, A.M., Kwong, P.D., Thompson, A., Lehmann, M.S., Grubel, G., Legrand, J.F., Alsnielsen, J., Colman, D.R., and Hendrickson, W.A. (1995). Structural basis of cell-cell adhesion by cadherins. Nature 374, 327-337.
45. Shapiro, L., Doyle, J.P., Hensley, P., Colman, D.R., and Hendrickson, W.A. (1996). Crystal structure of the extracellular domain from P0, the major structural protein of peripheral nerve myelin. Neuron 17, 435-449.
46. Simmons, D.L. (1993). Cloning cell surface molecules by transient expression in mammalian cells. In Cellular Interactions in Development, D. Hartley, ed. (Oxford: Oxford University Press), pp. 93-128.
47. Sjoberg, E.R., Powell, L.D., Klein, A., and Varki, A. (1994). Natural ligands of the B-cell adhesion molecule CD22β can be masked by 9-O-acetylation of sialic acids. J. Cell. Biol. 126, 549-562.
48. Springer, T.A. (1990). Adhesion receptors of the immune-system. Nature 346, 425-434.
49. Springer, T.A., and Lasky, L.A. (1991). Sticky sugars for selectins. Nature 349, 196-197.
50. Steiniger, B., Barth, P., Herbst, B., Hartnell, A., and Crocker, P.R. (1997). The species specific structure of microanatomical compartments in the human spleen: strongly sialoadhesin-positive macrophages occur in the perifollicular zone, but not in the marginal zone. Immunology 92, 307-316.
51. Takeichi, M. (1990). Cadherins: a molecular family important in selective cell-cell adhesion. Annu. Rev. Biochem 59, 237-252.
52. Takeichi, M. (1991). Cadherin cell-adhesion receptors as a morphogenetic regulator. Science 251, 1451-1455.
53. Tang, S., Shen, Y.J., DeBellard, M.E., Mukhopadhyay, G., Salzer, J.L., Crocker, P.R., and Filbin, M.T. (1997). Myelin-associated Glycoprotein interacts with neurons via a sialiac acid binding site at ARG118 and a distinct neurite inhibition site. J. Cell. Biol. 138, 1355-1366.
54. Tyrrell, D., James, P., Rao, N., Foxall, C., Abbas, S., Dasgupta, F., Nashed, M., Hasegawa, A., Kiso, M., Asa, D., Kidd, J., and Brandley, B.K. (1991). Structural requirements for the carbohydrate ligand of E-selectin. Proc. Nat. Acad. Sci. USA 88, 10372-10376.
55. Van den Berg, T.K., Breve, J.J.P., Damouseaux, J.G.M.C., Doop, E.A., Kelm, S., Crocker, P.R., Dijkstra, C.D., and Krall, G. (1992). Sialoadhesin on macrophages: its identification as a lymphocyte adhesion molecule. J. Exp. Med. 176, 647-655.
56. van der Merwe, P.A., Crocker, P.R., Vinson, M., Barclay, A.N., Schauer, R., and Kelm, S. (1996). Localization of the putative sialic acid-binding site on the immunoglobulin superfamily cell-surface molecule CD22. J. Biol. Chem. 271, 9273-9280.
57. Vinson, M., van der Merwe, P.A., Kelm, S., May, A., Jones, E.Y., and Crocker, P.R. (1996). Characterization of the sialic-binding site in sialoadhesin by site-directed mutagenesis. J. Biol. Chem. 271, 9267-9272.
58. Weis, W.I., and Drickamer, K. (1996). The structural basis of lectin-carbohydrate recognition. Annu. Rev. Biochem. 65, 441-473.
59. Williams, A.F., and Barclay, A.N. (1988). The immunoglobulin superfamily: domains for cell-surface recognition. Annu. Rev. Immunol. 6, 381-405.
60. Wright, C.S. (1990). 2.2 Å-resolution structure analysis of 2 refined N-acetylneuraminyllactose-wheat-germ-agglutinin isolectin complexes J. Mol. Biol. 215, 635-651.